Results 191 to 200 of about 16,658,609 (280)

Endotheliopathy in CAR T-Cell Therapy: Mechanistic Insights into the VWF/ADAMTS13 Axis and the Angiopoietin-Tie2 Pathway. [PDF]

TH Open
de Bruijn S, Vangenechten I, Anguille S, Gadisseur A.   +3 more
europepmc   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

CAR T-cell therapy induced pseudoprogression. [PDF]

Front Immunol
Dean EA.
europepmc   +1 more source

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng, Wen Gao, Jonathan Do, Danli Lu, Ying‐Wei Lan, Andreas Damianos, Gautam Verma, Ali Al Siraj, Isabella Lowry, Lance Peter, Nicholas E. Banovich, Fei Sun, Hua He, Tanya V. Kalin, Vladimir V. Kalinichenko   +14 more
wiley   +1 more source

Challenges and advances in CAR-T cell therapy for B-ALL. [PDF]

Biomark Res
Zha C, Wang Y.
europepmc   +1 more source

Impact of Histopathological Response on Outcomes After Surgical Resection Following Carbon‐Ion Radiotherapy for Pancreatic Cancer With Arterial Involvement

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Carbon‐ion radiotherapy (CIRT) provides superior dose distribution and higher biological effectiveness than conventional X‐ray radiotherapy and has emerged as a promising component of multidisciplinary treatment for advanced pancreatic ductal adenocarcinoma (PDAC).
Kenichiro Araki, Norio Kubo, Yuhei Miyasaka, Hayato Ikota, Ryo Muranushi, Mariko Tsukagoshi, Takamichi Igarashi, Masahiko Okamoto, Tatsuya Ohno, Ken Shirabe   +9 more
wiley   +1 more source

Association of Ferritin Levels With Cytokine Release Syndrome in CAR T-Cell Therapy: A Systematic Review and Meta-Analysis. [PDF]

Cancer Med
Sah R, Bhattarai A, Shah S, Mehta R, Sah S, Solangi Z, Sorescu GP.   +6 more
europepmc   +1 more source

DeepMapper: Attention‐Based AutoEncoder for System Identification in Wound Healing and Stage Prediction

Advanced Intelligent Discovery, EarlyView.
The authors develop a deep learning model for real‐time tracking of wound progression. The deep learning framework maps the nonlinear evolution of a time series of images to a latent space, where they learn a linear representation of the dynamics. The linear model is interpretable and suitable for applications in feedback control.
Fan Lu, Ksenia Zlobina, Michael Briden, Oscar Avalos, Héctor Carrión, Sebastian Osorio, Hsin‐ya Yang, Alexandra Nava, Michelle D. Bagood, Marco Rolandi, Roslyn Rivkah Isseroff, Marcella Gomez   +11 more
wiley   +1 more source

Nursing insights into CAR T-cell therapy for systemic lupus erythematosus: Highlights of a standardized nursing system for CAR T-cell therapy. [PDF]

Rheumatol Immunol Res
Yang Y, Gao L, Wang K, Li X.
europepmc   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source