Results 241 to 250 of about 16,658,609 (280)

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Retraction Note: Hurdles to breakthrough in CAR T cell therapy of solid tumors. [PDF]

Stem Cell Res Ther
Marofi F, Achmad H, Bokov D, Abdelbasset WK, Alsadoon Z, Chupradit S, Suksatan W, Shariatzadeh S, Hasanpoor Z, Yazdanifar M, Shomali N, Khiavi FM.   +11 more
europepmc   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications. [PDF]

Int J Lab Hematol
Du W, Koga S, Yang G, Gill S, Bagg A.
europepmc   +1 more source

CAR-T cell therapy in cancer immunotherapy - Biology, clinical successes, and emerging challenges: A review. [PDF]

Biomol Biomed
Bedada AT, Mehdi M, Mohammed O.
europepmc   +1 more source

Risk of thrombosis and bleeding following CAR T-cell therapy: Insights from the Dutch "Follow that CAR!" registry. [PDF]

Hemasphere
Ko AK, Mutsaers PGNJ, van Kleij LM, Vledder A, Pennings ERA, Spanjaart AM, de Boer JW, Keijzer K, Demandt AMP, van Doesum JA, van Dorp S, Jak M, Kuipers MT, van Meerten T, van der Poel MWM, Vermaat JSP, Leebeek FWG, Kersten MJ, Lauw MN.   +18 more
europepmc   +1 more source

Advancing targeted protein degradation: pLIRTAC's role in glioma and CAR-T cell therapy. [PDF]

Autophagy
Lei K, Li Y, Zhou Z, Li J, Huang L, Liu W, Huang K, Zhu X.   +7 more
europepmc   +1 more source

Epigenetic editing to advance CAR T cell therapy. [PDF]

Clin Epigenetics
Horvathova L, Rots MG, Wiersma VR.
europepmc   +1 more source

Recent advances in molecular mechanisms to improve the efficacy of CAR-T cell therapy for viral diseases, cancer, and autoimmune diseases. [PDF]

Stem Cell Res Ther
Marei HE, Pozzoli G, Caratelli S, Cenciarelli C.   +3 more
europepmc   +1 more source