Results 61 to 70 of about 4,213,151 (329)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Assessment of chimeric antigen receptor T (CAR-T) cytotoxicity by droplet microfluidics in vitro [PDF]

open access: gold, 2021
Kuan Un Wong   +7 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Modular Robot System for Maintenance Tasks in Large Scientific Facilities

open access: yesInternational Journal of Advanced Robotic Systems, 2013
Large scientific facilities such as particle accelerators are scenarios that require continuous maintenance and specific type of interventions. The intervening personnel are sometimes required to work exposed to residual radiation.
Prithvi Sekhar Pagala   +3 more
doaj   +1 more source

Role of quantum nuclei and local fields in the x-ray absorption spectra of water and ice

open access: yes, 2012
We calculate the x-ray absorption spectra of liquid water at ambient conditions and of hexagonal ice close to melting, using a static GW approach that includes approximately local field effects.
J. Stohr   +3 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

M\"obius molecules and fragile Mott insulators

open access: yes, 2014
Motivated by the concept of M\"obius aromatics in organic chemistry, we extend the recently introduced concept of fragile Mott insulators (FMI) to ring-shaped molecules with repulsive Hubbard interactions threaded by a half-quantum of magnetic flux ($hc ...
Car, Roberto   +3 more
core   +1 more source

Car Sharing

open access: yes, 2016
ISBN:978-1-909188-76 ...
Ciari, Francesco, Balać, Miloš
openaire   +3 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Car wash water recycling system [PDF]

open access: yes, 2020
The high rate of transportation and vehicle washing centers led to an increase in water consumption. When the water consumption increase, the amount of wastewater discharged and the cost of utility will also increase.
Adam, Nur Farah Aqilah   +4 more
core  

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