Results 201 to 210 of about 21,080,479 (286)

Supramolecular Cadmium‐Telluride Proteoliposomal Assemblies for Real‐Time Detection of Protein‐Catalyzed Pt(II)‐Complexes Transmembrane Translocation: Cu(I)‐Pumps Are Electrogenic Pt(II)‐Drug Uniporters

Angewandte Chemie, EarlyView.
Supramolecular mercaptosuccinic acid‐capped CdTe core‐type quantum dot‐encapsulated proteoliposome assemblies (MSA‐CdTe QD PLs) have been developed to study and unambiguously demonstrate real‐time transporter‐mediated turnover translocation of Pt(II)‐based complexes by transmembrane Cu(I) P‐type ATPase pumps (CopA).
Madujika A. Horadigala Gamage, Alessandra Barbanente, Nadeesha T. Liyana Withanage, Yalini H. Wijesundara, Jeremiah J. Gassensmith, Fabio Arnesano, Giovanni Natile, Gabriele Meloni   +7 more
wiley   +2 more sources

The TCR in CAR T cell therapy: use it or lose it? [PDF]

Cancer Gene Ther
Liseth O, Vile R.
europepmc   +1 more source

Translational Macrophage Mechano‐Immunotherapy for Next‐Generation Implantable Biomaterials

Advanced NanoBiomed Research, EarlyView.
This review explores how macrophage mechanosensing drives inflammation, fibrosis and foreign body responses to implanted biomaterials. It examines emerging pharmacological strategies to modulate mechanotransduction, alongside biomaterial platforms for localised drug delivery, clinical translation, regulatory considerations and standardised testing ...
Xueying Xu, Ian L. Chin, Richard P. Tan
wiley   +1 more source

Magnetic Resonance Reveals Radical Stability in Native Biofilms and Its Role in Bacterial Resistance

Angewandte Chemie, EarlyView.
The complex biofilm environment consists of planktonic bacterial cells and cells embedded in an extracellular matrix (ECM). Through an integrated magnetic resonance approach, we show that nitroxide radicals primarily interact with the polysaccharides and lipids in the ECM.
Alysia Mandato, Hannah Hunter, Sadhana Srinivasa, Chang‐Hyeock Byeon, Abdulkadir Tunc, Meghan K. Wells, Faith J. Scott, Frederic Mentink‐Vigier, Wook Kim, Sunil Saxena, Ümit Akbey   +10 more
wiley   +2 more sources

The future directions of CAR-T Cell therapy: unlocking the potential of immunotherapy in cancer treatment. [PDF]

Front Mol Med
Justiz-Vaillant AA, Soodeen S, Arozarena-Fundora R, Akpaka PE, Unakal C.   +4 more
europepmc   +1 more source

Selective Cell‐Repellent 3D Scaffold Platform for Proton Radiobiology

Advanced NanoBiomed Research, EarlyView.
A selective cell‐repellent 3D scaffold platform is developed to minimize unwanted 2D cell populations surrounding engineered cell microenvironments. The approach is based on the combination of Lipidure coatings with two‐photon polymerized scaffolds and enables specific characterization of glioblastoma cells’ response to proton irradiation.
Novinda S. Pertiwi, Qais Akolawala, Rob van den Akker, Anggraeini Puspitasari‐Kokko, Henri H. Versteeg, Araci M. R. Rondon, Angelo Accardo   +6 more
wiley   +1 more source

CAR T-Cell Therapy

Oncology Times, 2017
openaire   +2 more sources

Transient Atrioventricular Block Secondary to Coronary Artery Embolism From Infective Endocarditis Following CAR T-Cell Therapy. [PDF]

J Arrhythm
Kito K, Tsutsui K, Matsuyama T, Ban A, Kobayashi K, Hatsuno M, Haga T, Sasajima Y, Kozuma K.   +8 more
europepmc   +1 more source

Mechanisms, optimization strategies, and salvage options for CAR-T cell therapy. [PDF]

Biomark Res
Wu B, Wang J, Zou Q, Cai J, Zhang Y, Zhong Q, Bai B, Liu F, Cao Y, Li P, Dai DL, Cai Q.   +11 more
europepmc   +1 more source