Results 31 to 40 of about 2,800,842 (310)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Urban Science, 2022 There are significant deviations in travel mode choice drivers between developed and developing countries. This study investigates the determinants of car ownership and public transit ridership in Iran.
Houshmand Masoumi +4 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Passenger Transport Trends in the V4 Countries
Logi, 2023 Passenger transport, or efforts to modify it in order to minimize its negative environmental impact, is a discussed issue. This paper aims to assess the trends in passenger transport indicators in the V4 countries between1995 and 2018.
Komorousová Veronika, Hinke Jana
doaj +1 more source
Car Sharing as a Key Contribution to Multimodal and Sustainable Mobility Behavior – the Situation of Car Sharing in Germany [PDF]
, 2006 So far, car sharing is just a small niche product on the mobility market. The proven positive effects of car sharing can only contribute to solving traffic problems if the number of car sharing customers grows.
Nobis, Claudia
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Applied SciencesThe present study focuses on scientific and experimental research on corrosion damage to the bodies of subway cars. The main purpose of the research is to assess the degree of corrosive wear on the main load-bearing metal structures of the subway cars ...
Andrii Sulym +5 more
doaj +1 more source
Car Use: A Matter of Dependency or Choice? The Case of Commuting in Noord-Brabant
Urban Planning, 2023 Car use in the sprawled urban region of Noord-Brabant is above the Dutch average. Does this reflect car dependency due to the lack of competitive alternative modes? Or are there other factors at play, such as differences in preferences? This article aims
Hossein Dashtestaninejad +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Analysis of Socio-spatial Differentiation in Transport Mode Choice Preferences
Promet (Zagreb), 2017 Starting from the fact that the transport mode choice is one of those aspects of travel behaviour that, to a great extent, affects the efficiency of the transport system, this paper analyses the factors that contribute to the use of public and car ...
Geran-Marko Miletić +2 more
doaj +1 more source