Results 121 to 130 of about 14,304 (180)

Carbachol in Cataract Surgery

Archives of Ophthalmology, 1968
Carbachol in a weak dilution (0.01%) is effective and relatively nonirritating when used as a miotic after the lens is removed in round pupil cataract extraction.
H, Beasley, A R, Borgmann, T O, McDonald, P R, Belluscio   +3 more
openaire   +2 more sources

Bidirectional transfer of electrical and carbachol kindling

Brain Research, 1983
In two experiments rats were kindled by electrical stimulation or the infusion of carbachol, and subsequently rekindled by carbachol or electrical stimulation, respectively, in the amygdala. The rats that previously had been kindled using one agent kindled significantly faster and displayed significantly stronger seizures when rekindled using the other
D P Cain, Donald P Cain
exaly   +3 more sources

Learned aversions to intracerebral carbachol

Physiology & Behavior, 1977
Abstract The learned taste aversion paradigm was employed to test for aversive effects of microinjections of carbachol to the medial septum, lateral ventricle and ventral hippocampus. To determine the locus of action of carbachol, either a central cholinergic blocker (atropine sulfate) or a peripheral cholinergic blocker (atropine methyl nitrate) was
R H, Myers, J M, De Castro
openaire   +2 more sources

Comparison of intraocular acetylcholine and carbachol

Journal of Cataract and Refractive Surgery, 1986
Commercially available 1% acetylcholine chloride and 0.01% carbachol chloride, which are commonly used as miotics in intraocular surgery, have recently been reformulated. Comparative studies of these agents show similar miotic activity. However, in vitro perfusion of human corneas demonstrated that 1% acetylcholine chloride causes marked changes in ...
R W, Yee, H F, Edelhauser
openaire   +2 more sources

Determination of Carbachol in Aqueous Solution

Journal of Pharmaceutical Sciences, 1969
A more specific method of analysis of carbachol (carbamylcholine chloride) in aqueous solution is reported. The procedure requires the chlorination of the free N—H moiety which in turn is utilized to oxidize iodide to iodine. Quantitation is then accomplished by reacting this latter product with starch and measuring the resultant blue color.
R, Puckett, R D, Poe
openaire   +2 more sources

Central hyperglycemic effect of carbachol in rats

European Journal of Pharmacology, 1976
Intraventricular injection of carbachol produces hyperglycemia in rats at doses which are ineffective when given subcutaneously. This effect is suppressed by intraventricular administration of small amounts of atropine, further supporting the suggestion that the effect of carbachol is due to its action on central cholinergic receptors.
M Körner
exaly   +3 more sources

Carbachol☆

2007
Carbachol is a structural analog of acetylcholine and has agonist activity at muscarinic and nicotinic cholinergic receptors. It is like acetylcholine in being a quaternary amine and having a positive charge at all pH values. A major difference from acetylcholine is that carbachol is not hydrolyzed by cholinesterases.
openaire   +2 more sources

Pharmacological Studies on N-Demethylated Carbachol

Journal of Pharmaceutical Sciences, 1978
In attempts to find a drug more active than pilocarpine, the tertiary nitrogen derivative of carbachol, N-demethylated carbachol, was synthetized and tested on several autonomic nervous system preparations. N-Demethylated carbachol was active at muscarinic and nicotinic sites in vivo and in vitro.
C Y Chiou
exaly   +3 more sources

Carbachol effects on hippocampal neurons in vitro: dependence on the rate of rise of carbachol tissue concentration

Experimental Brain Research, 1988
Nominally K-sensitive microelectrodes were used to measure carbachol (CCh) in order to study the dependence of muscarinic effects on CCh concentration and exposure time in guinea pig hippocampal slices. Interference presumably originating from tissue choline-compounds was neutralized by pre-equilibration of the slices with 500 microM choline and ...
W, Müller, U, Misgeld, U, Heinemann
openaire   +2 more sources