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Dual effects of carbachol on cytosolic Ca2+ and contraction in intestinal smooth muscle
The effects of carbachol on muscle tension and cytosolic Ca2+ concentrations ([Ca2+]cyt), measured with fura-2, were examined in the guinea pig intestinal smooth muscle. Carbachol induced an initial transient increase followed by a sustained increase in [
M. Mitsui, H. Karaki
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SCG in carbachol-induced bronchoprovocation in asthmatic children
Ten children with mild bronchial asthma underwent bronchial challenge with carbachol on three consecutive days; using a double-blind technique, they were given inhaled saline placebo on the first day and placebo or sodium cromoglycate (SCG) on the second
F. ZACCHELLO +4 more
core
Protein release from the rat exocrine pancreas was stimulated in vitro by carbachol or dibutyryl cyclic AMP (DBC); secretion caused by a combination of these two agents was greater than the sum of their individual effects.
Fast, Diane K.
core
Background: It has been clearly documented that Elaegnaceae have a variety of medicinal uses including anti-ulcerogenic activity. Objective: We therefore hypothesized that Elaeagnus angustifulia L. (E.
A Eliassi, M Mandipour, M Kamalinejad
doaj
EFFECT OF CARBACHOL ON REFLEX VASOMOTOR STIMULATION
CHANDRA, OM, GUPTA, K.P., SINGHAL, K.C.
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Carbachol is a structural analog of acetylcholine and has agonist activity at muscarinic and nicotinic cholinergic receptors. It is like acetylcholine in being a quaternary amine and having a positive charge at all pH values. A major difference from acetylcholine is that carbachol is not hydrolyzed by cholinesterases.
Donald Hoover, Hoover, Donald
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Bidirectional transfer of electrical and carbachol kindling
Brain Research, 1983In two experiments rats were kindled by electrical stimulation or the infusion of carbachol, and subsequently rekindled by carbachol or electrical stimulation, respectively, in the amygdala. The rats that previously had been kindled using one agent kindled significantly faster and displayed significantly stronger seizures when rekindled using the other
D P Cain, Donald P Cain
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Central hyperglycemic effect of carbachol in rats
European Journal of Pharmacology, 1976Intraventricular injection of carbachol produces hyperglycemia in rats at doses which are ineffective when given subcutaneously. This effect is suppressed by intraventricular administration of small amounts of atropine, further supporting the suggestion that the effect of carbachol is due to its action on central cholinergic receptors.
M Körner
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