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IR Spectrophotometric Assay of Carbachol Solutions
Journal of Pharmaceutical Sciences, 1977Carbachol ophthalmic solutions can be assayed by evaporating a measured volume, dissolving the residue in methanol, and scanning the carbonyl stretching frequency in an IR spectrophotometer using a cell with calcium fluoride windows. Methylcellulose and other formulation vehicle components do not interfere.
J, Frank, L, Chafetz
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Atropine antagonism of carbachol-induced hyperglycemia
Journal of Pharmaceutical Sciences, 1967Hyperglycemia was induced with carbachol in rats, rabbits, and dogs, and the effect in rabbits was shown to be dose related. In albino rabbits with negligible plasma esterase activity, atropine sulfate effectively prevented hyperglycemia following 25 mcg./Kg. of carbachol, and the effect appeared to be dose dependent.
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Corneal Edema After Use of Carbachol
Archives of Ophthalmology, 1979To the Editor. —In a recent issue of theArchives(96:1897-1901,1978) Vaughn et al described their experimental data on the perfusion of the anterior chamber of rabbits with carbachol. They noted transitory but reversible swelling of the cornea, which implied some transitory endothelium dysfunction.
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Effect of carbachol on postoperative intraocular pressure
Journal of Cataract and Refractive Surgery, 1988Carbachol instilled in 125 eyes at the time of extracapsular cataract extraction and posterior chamber lens insertion had a statistically significant effect on lowering the postoperative intraocular pressure (IOP) at 24 hours (average IOP 14.0 mm Hg) and at 72 hours (average IOP 11.6 mm Hg) (P less than .001).
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Intracellular records of carbachol-induced theta rhythm in hippocampal slices
Brain Research, 1988Jan Konopacki +2 more
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