Results 181 to 190 of about 16,333 (208)
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The subfornical organ and carbachol-induced drinking
Brain Research, 1972Summary The initial report of Routtenberg and Simpson 32 indicated that exogenous carbamylcholine chloride (carbachol) applied directly to 3rd ventricle or subfornical organ elicited drinking behavior. The possibility that subfornical organ was the site of action of the carbachol was more thoroughly investigated in this study.
John B. Simpson, Aryeh Routtenberg
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Effect of carbachol on postoperative intraocular pressure
Journal of Cataract and Refractive Surgery, 1988Carbachol instilled in 125 eyes at the time of extracapsular cataract extraction and posterior chamber lens insertion had a statistically significant effect on lowering the postoperative intraocular pressure (IOP) at 24 hours (average IOP 14.0 mm Hg) and at 72 hours (average IOP 11.6 mm Hg) (P less than .001).
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Atropine antagonism of carbachol-induced hyperglycemia
Journal of Pharmaceutical Sciences, 1967Hyperglycemia was induced with carbachol in rats, rabbits, and dogs, and the effect in rabbits was shown to be dose related. In albino rabbits with negligible plasma esterase activity, atropine sulfate effectively prevented hyperglycemia following 25 mcg./Kg. of carbachol, and the effect appeared to be dose dependent.
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Pre- and postjunctional neuromuscular blockade by carbachol
Naunyn-Schmiedeberg's Archives of Pharmacology, 1975Carbachol, when applied to the bathing Ringer solution of frog sartorius muscles, caused depolarization of the endplate and a blockade of endplate potentials (EPP's), miniature EPP's (mepp's) and the iontophoretic acetylcholine potential. In muscles treated with an analog of hemicholinium-3, alpha, alpha'bis(dimethylammonium acetaldehyde diethylacetal)-
Edward G. Henderson, Robert L. Volle
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Carbachol dimers as homobivalent modulators of muscarinic receptors
Biochemical Pharmacology, 2016A series of homodimers of the well-known cholinergic agonist carbachol have been synthesized, showing the two agonist units symmetrically connected through a methylene chain of variable length. The new compounds have been tested on the five cloned muscarinic receptors (hM1-5) expressed in CHO cells by means of equilibrium binding studies, showing an ...
MATUCCI, ROSANNA +11 more
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Corneal Edema After Use of Carbachol
Archives of Ophthalmology, 1979To the Editor. —In a recent issue of theArchives(96:1897-1901,1978) Vaughn et al described their experimental data on the perfusion of the anterior chamber of rabbits with carbachol. They noted transitory but reversible swelling of the cornea, which implied some transitory endothelium dysfunction.
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Use of carbachol for dilatation of the cervix in heifers
Theriogenology, 1980Abstract Thirty-one heifers were injected s.c. with 2.5 to 3.0 ml of carbachol (Hormotonin, SPOFA) on days 7 to 9 of the estrous cycle to test its dilative effect on the cervix. The state of the cervix was assessed by means of a metal probe before and after carbachol administration.
Z. Veznik, Z. Zraly, V. Kummer
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Hyperthyroidism Protects Against Carbachol-Induced Bronchospasm
Chest, 1987We studied the effect of increased thyroid function on airway reactivity. Carbachol challenge was performed to assess airway reactivity according to a standardized method. Measurements of forced expiratory volume-1 second (FEV1), specific airway conductance (SGaw), the provocative dose of carbachol for a 20 percent decrease in FEV1 (PD-20) and that for
Robert H. Israel +4 more
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Rapid activation of gluconeogenesis after intracerebroventricular carbachol
American Journal of Physiology-Endocrinology and Metabolism, 1989Intracerebroventricular administration of carbachol (27 nmol in 5 microliters 0.15 M NaCl) produced marked hyperglycemia in 24-h fasted rats, despite the negligible amounts of preformed liver glycosyl residues. To investigate the possibility of a stimulation of gluconeogenesis, conscious unrestrained rats were continuously infused with [14C]bicarbonate
J E S Roselino +3 more
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Characterization of the Antinociception Induced by Intrathecally Administered Carbachol
Pharmacology & Toxicology, 1989Abstract:The antinociceptive effect of intrathecally administered carbachol at the L1/L2 level in the rat was evaluated using the tail immersion test. A dose dependent increase in the nociceptive reaction times was evident following intrathecal carbachol in the dose range of 2.5–15 μg.
Per-Göran Gillberg +5 more
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