Results 141 to 150 of about 47,769 (294)

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Ocular Neuromyotonia—A Rare but Reversible Cause of Intermittent Diplopia

Movement Disorders Clinical Practice, EarlyView.
Parthvi Ravat, Paul Stockle, Mahadya Rahman, Pegah Ahmadiyan Ardestani, Andrew Lee   +4 more
wiley   +1 more source

Development and Verification of Virtual Population Models for Predicting Drug Pharmacokinetics in Ethnic North American Populations

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Ethnic variabilities can affect the outcome of drug pharmacokinetics (PK) and drug–drug interactions (DDI). This work aimed to develop four North American (NA) sub‐populations: White, African American, Asian American, and Hispanic_Latino suitable for physiologically based pharmacokinetic (PBPK) modeling and simulations.
Udoamaka Ezuruike, Jean Dinh, Eman El‐Khateeb, Alex Blenkinsop, Oliver Hatley, Iain Gardner   +5 more
wiley   +1 more source

Factors Influencing Simultaneous Concentrations of Carbamazepine and Its Epoxide in Plasma

, 1981
Leigh McKauge, J. H. Tyrer, Mervyn J. Eadie   +2 more
openalex   +1 more source

Abrupt and Severe Onset of Dystonia, Chorea and Hemiplegic Episodes in a Young Boy with a Novel Heterozygous Missense Variant in the GTPase Domain of RHOBTB2

Movement Disorders Clinical Practice, EarlyView.
Phuong T. Hoang, Ian O. Bledsoe, Marta San Luciano   +2 more
wiley   +1 more source

Sustainable Biomass‐Derived Single‐Atom Catalysts for Fenton‐Like Catalysis

Small, EarlyView.
The review comprehensively examines synthesis methods for biomass‐derived transition metal‐based singleatom catalysts (SACs). It narrows focus to Fenton‐like reactions, emphasizing how synthesis‐property relationships and active site configurations influence reaction mechanisms and catalytic performance, offering insight into the design of SACs for ...
Selusiwe Ncube, Zhihao Tian, Jingkai Lin, Huayang Zhang, Shaobin Wang, Wenjie Tian   +5 more
wiley   +1 more source

The Effect of Phenytoin and Carbamazepine on Serum Dehydroepiandrosterone Sulfate in Men and Women Who Have Partial Seizures with Temporal Lobe Involvement *

, 1986
Linda Levesque, Andrew G. Herzog, Markus J. Seibel   +2 more
openalex   +1 more source

Effects of Antiepileptic Drugs, Carbamazepine and Phenytoin, on Plasma Concentrations of Clozapine and Its N-Desmethyl and N-Oxide Metabolites in Japanese Patients With Schizophrenia. [PDF]

Neuropsychopharmacol Rep
Ikawa K, Imura T, Nakamura S, Murata K, Morikawa N, Sakata M, Yasuzawa H, Horikawa N.   +7 more
europepmc   +1 more source

Determinants of carbamazepine and carbamazepine 10,11‐epoxide binding to serum protein, albumin and alpha 1‐acid glycoprotein.

, 1984
JJ MacKichan, EM Zola
openalex   +1 more source

Predictors of Compliance with Lithium and Carbamazepine Regimens in the Long-Term Treatment of Recurrent Mood and Related Psychotic Disorders [PDF]

, 1989
A. Lenzi, F. Lazzerini, G. Placidi, G. Cassano, H. Akiskal   +4 more
openalex   +1 more source