Anticonvulsant potential of rosuvastatin in combination with carbamazepine and valproate in animal models of epilepsy. [PDF]
Tayal V+5 more
europepmc +1 more source
The interaction of phenytoin and carbamazepine with combined oral contraceptive steroids. [PDF]
Pamela Crawford+5 more
openalex +1 more source
Biallelic COL4A2 Variants Associated With Brain Small Vessel Disease and Brain Malformations
Biallelic COL4A2 variants cause a spectrum of brain abnormalities such as brain small vessel disease (BSVD). We describe two cases—one with cerebrovascular disruption and one with cortical malformations—expanding the recessive phenotype. Protein modeling reveals destabilization by p.(Arg179Cys), reinforcing its pathogenic role and highlighting collagen
Anees Muhammad+11 more
wiley +1 more source
Sensitivity of Tepotinib to Inhibitors or Inducers of CYP3A4 and P-Gp: Drug Interaction Studies and Physiologically-Based Pharmacokinetic Analysis. [PDF]
Strotmann R+8 more
europepmc +1 more source
Sick sinus syndrome aggravated by carbamazepine therapy for epilepsy
K A Hewetson, Alistair Ritch, R. Watson
openalex +1 more source
Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment. The pathogenesis of these lesions encompasses a range of causes, including haemorrhagic, embolic, or other vascular events; exposure to teratogens, such as drugs or substance
Ana Alarcón+33 more
wiley +1 more source
Evaluation of Antiepileptic Drugs' Stability in Oral Fluid Samples. [PDF]
Martinho J+3 more
europepmc +1 more source
Relationship between systemic drug absorption and gastrointestinal transit after the simultaneous oral administration of carbamazepine as a controlled‐release system and as a suspension of 15N‐labelled drug to healthy volunteers. [PDF]
IR Wilding+8 more
openalex +1 more source
ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus has been implicated in a mitochondrial disorder characterized by prenatal or ...
Pauline Planté‐Bordeneuve+26 more
wiley +1 more source
Pharmacokinetic study of carbamazepine and its epoxide metabolite in humans.
Masahiro Sumi+3 more
openalex +2 more sources