Results 161 to 170 of about 61,637 (294)

Widespread decoupling of spindles and slow waves in temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Memory impairment is common in people with temporal lobe epilepsy (TLE). Recent studies in healthy subjects showed a positive correlation between sleep spindles coupled to slow waves (SWs) and memory performance. We aimed to determine differences in spindle–SW coupling in TLE patients compared to healthy controls using combined high ...
Katharina Schiller   +9 more
wiley   +1 more source

Medication‐resistant epilepsy is associated with a unique gut microbiota signature

open access: yesEpilepsia, EarlyView.
Abstract Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the composition of the gut microbiota in a cohort of medication‐resistant (MR) and medication‐sensitive (MS) pediatric patients with epilepsy.
Antonella Riva   +14 more
wiley   +1 more source

Carbamazepine-related antiepileptic drugs for the treatment of epilepsy - a comparative review

open access: yesExpert Opinion on Pharmacotherapy, 2016
Jaime Gierbolini   +2 more
semanticscholar   +1 more source

Long‐term seizure and psychosocial outcomes of patients with ring chromosome 20 syndrome: A cohort study of 47 cases

open access: yesEpilepsia, EarlyView.
Abstract Objective We retrospectively investigated a cohort of patients with ring chromosome 20 syndrome (r20), aiming to provide information on the prognosis of r20 regarding seizures, cognitive function, comorbidities, and social living. Methods Patients diagnosed with r20 in our hospital were identified, and clinical data were extracted from medical
Kentaro Tokumoto   +11 more
wiley   +1 more source

Tailoring antiseizure treatment with a wearable device: A proof‐of‐concept study in absence epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Typical absence seizures are underreported. We aimed to improve patient care using a wearable electroencephalograph (wEEG) at home and assess a machine learning (ML) pipeline for absence detection. Methods Patients with typical absences used a wEEG device 12–24 h 1 week after antiseizure medication (ASM) adjustments.
Jaiver Macea   +4 more
wiley   +1 more source

EEG signal dimension is an index of seizure propensity and antiseizure medication effects in a mouse model of acquired epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Variability in the frequency, timing, and pattern of seizures may influence the assessment of the effect of antiseizure medications (ASMs) when measuring seizure frequency, especially in patients with infrequent seizures. A low seizure rate is an exclusion criterion for enrollment of patients with epilepsy in clinical trials and ...
Massimo Rizzi   +4 more
wiley   +1 more source

An Evaluation of Cation-Chloride Cotransporters NKCC1 and KCC2 in Carbamazepine-Resistant Rats. [PDF]

open access: yesInt J Mol Sci
Zavala-Tecuapetla C   +3 more
europepmc   +1 more source

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