Results 221 to 230 of about 120,317 (381)

PAC‐FOS: A novel translational concordance framework identifies preclinical seizure models with highest predictive validity for clinical focal onset seizures

Epilepsia, EarlyView.
Abstract Objective Central to the development of novel antiseizure medications (ASMs) is testing of antiseizure activity in preclinical models. Although various well‐established models exist, their predictive validity across the spectrum of clinical epilepsies has been less clear.
Lyndsey L. Anderson, Kristopher M. Kahlig, Melissa L. Barker‐Haliski, Lillian G. Matthews, Hamish D. Toop, Brian Hannigan, Jacqueline French, H. Steve White, Marcio Souza, Steven Petrou   +9 more
wiley   +1 more source

Prescription Patterns of Antiseizure Medication in Adult Patients with Epilepsy in Kazakhstan (2021-2023). [PDF]

Med Sci (Basel)
Kalinina D, Aimyshev T, Muxunov A, Utebekov Z, Kyrgyzbay G, Kimadiev D, Zhumabaeva G, Gaipov A, Sarria-Santamera A.   +8 more
europepmc   +1 more source

Paroxysmal slow wave events as a diagnostic biomarker for epilepsy: Lessons from rural Zambia

Epilepsia, EarlyView.
Abstract Objective Epilepsy affects more than 50 million people globally, with low‐ and middle‐income countries (LMICs) bearing the greatest burden due to limited medical resources and stigma. Electroencephalography (EEG) is a cost‐effective diagnostic tool, but its interpretation often requires unavailable expertise in rural areas. There is a pressing
Andrew Malunga, Sina Lash, Alaa Abu‐Ahmad, Laith Alhadeed, Felix Benninger, Gal Ben‐Arie, Nicholas Fearns, Hamza Imtiaz, Stefan Kunst, Anna Minarik, Mutale Masamu, George Mshanga, Oliver Neal, Attila Racz, Theodor Ruber, Khalid Saadeh, Yonatan Serlin, Merav Shamir, Tamara Welte, Benjamin Whatley, Alon Friedman, Stanley Zimba   +21 more
wiley   +1 more source

Trigeminal root demyelination is sufficient to induce trigeminal neuralgia-like facial pain in adult rodents. [PDF]

J Headache Pain
Wang ZY, Ding YQ, Wen JM, Zheng BW, Zhang K, Qi JG.   +5 more
europepmc   +1 more source

4β-hydroxycholesterol correlates with dose but not steady-state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation?

British Journal of Clinical Pharmacology, 2016
Caroline Gjestad, Duy Khanh Huynh, T. Haslemo, E. Molden   +3 more
semanticscholar   +1 more source

Long‐read sequencing of recurrent FGF12 duplications in epilepsy: Insights into structural mechanisms and aberrant isoforms

Epilepsia, EarlyView.
Abstract Objective Fibroblast growth factor 12 (FGF12), a member of the fibroblast homologous factor family, plays a key role in the modulation of voltage‐gated sodium (Nav) channels. Pathogenic variants in the FGF12 gene leading to a gain‐of‐function mechanism and partial duplication encompassing the FGF12 gene leading to a loss‐of‐function mechanism ...
Jade Fauqueux, Laurence Chaton, Pierre Cleuziou, Anne‐Sophie Diependaële, Nathalie Bach, Nicolas Gruchy, Marion Gerard, Jean‐Pascal Meneboo, Céline Villenet, Martin Figeac, Emilie Ait‐Yahya, Caroline Thuillier, Elise Boudry, Adeline Trauffler, Sylvie Nguyen‐The‐Tich, Simon Boussion, Roseline Caumes, Jamal Ghoumid, Thomas Smol   +18 more
wiley   +1 more source

Bioanalysis and Pharmacokinetics of Carbamazepine

, 1980
H.G.M. Westenberg
openalex   +1 more source

HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.

New England Journal of Medicine, 2011
M. McCormack, A. Alfirevic, Stephane Bourgeois, J. Farrell, Dalia Kasperavičiūtė, M. Carrington, G. Sills, T. Marson, Xiaoming Jia, P. D. Bakker, K. Chinthapalli, M. Molokhia, Michael R. Johnson, G. O’Connor, E. Chaila, S. Alhusaini, K. Shianna, R. Radtke, E. Heinzen, N. Walley, M. Pandolfo, W. Pichler, B. Park, C. Depondt, S. Sisodiya, D. Goldstein, P. Deloukas, N. Delanty, N. Delanty, G. Cavalleri, M. Pirmohamed   +30 more
semanticscholar   +1 more source

Feasibility and safety of awake craniotomy in adult patients with drug‐resistant focal epilepsy

Epilepsia, EarlyView.
Abstract Objective Although awake craniotomy can guide functional brain mapping and resection, its feasibility and safety have been poorly studied in large series of patients with drug‐resistant focal epilepsy surgery. Methods We conducted an observational, retrospective, single‐center cohort study of 588 consecutive awake craniotomies (2010–2024 ...
Marc Zanello, Gonzague De France, Angela Elia, Marco Demasi, Cristina Filipescu, Elisabeth Landre, Alessandro Moiraghi, Bénédicte Trancart, Maimiti Seneca, Agathe Guibert, Fabrice Chretien, Alexandre Roux, Johan Pallud   +12 more
wiley   +1 more source

Quantifying the risk of drug-associated skin hyperpigmentation relative to the general population: A national cohort study using TriNetX. [PDF]

JAAD Int
Cheng D, Ji H, Xiang D, Thang CJ, Zhang AD, Mostaghimi A, Semenov YR, Theodosakis N.   +7 more
europepmc   +1 more source