Results 51 to 60 of about 56,505 (288)

Ameliorative role of Omega-3 fatty acids and Vitamin E against Carbamazepine induced Hepatoxicity in Rats

Al-Mustansiriyah Journal of Pharmaceutical Sciences
Background: Carbamazepine has been utilized to treat epilepsy and neuralgic conditions. Drug-induced liver injury triggered by Carbamazepine. Drug-induced liver injury from Carbamazepine consequently leads to liver failure.
Furkan Majid AL Attar, Intesar Tarik Numan, Suhad Faisal Hatem Al- Mugdadi   +2 more
doaj   +1 more source

Neuroleptic Malignant Syndrome Caused by a Combination of Carbamazepine and Amitriptyline

Case Reports in Neurological Medicine, 2012
A 32-year-old female, with a history of secondarily-generalized convulsive epilepsy, mental retardation, and a psychiatric illness, developed neuroleptic malignant syndrome while receiving carbamazepine and amitriptyline concurrently. We hypothesize that
A. Bruce Janati, Naif ALGhasab, Aboubaker Osman   +2 more
doaj   +1 more source

Carbamazepine kinetics in cardiac patients before and during amiodarone

Arquivos de Neuro-Psiquiatria, 1994
Carbamazepine and amiodarone may often be used together, especially in countries where cardiomyopathies are common. In this study single doses of carbamazepine (400 mg) were given to patients with cardiac disease before and after one month of therapy ...
Silmara A.O. Leite, Paulo J.M. Leite, Gilberto A. Rocha, Philip A. Routledge, Paulo Rogério M. Bittencourt   +4 more
doaj   +1 more source

Association of polymorphisms in EPHX1, UGT2B7, ABCB1, ABCC2, SCN1A and SCN2A genes with carbamazepine therapy optimization

, 2014
Aim: Carbamazepine (CBZ) is one of the most widely used antiepileptic drugs. The aim of the present study is to investigate the impacts of polymorphisms in genes related to pharmacokinetic and pharmacodynamic pathways of CBZ on the large interindividual ...
戴政, Hung, Chin-Chuan;Chang, Wei-Lun;Ho, Jia-Ling;Tai, John Jen;Hsieh, Tsung-Jen;Huang, Hsiao-Ching;Hsieh, Yow-Wen;Liou, Horng-Huei   +1 more
core   +1 more source

Assessment of adherence to carbamazepine using plasma and saliva samples, a study from Jordan

Heliyon
Background: The measurement of carbamazepine levels in a biological sample is required to guide dosing, and prevent toxicity, and can be useful to assess medication adherence. Aim: The primary aim of the presented study is to analyze carbamazepine levels
Ghaith M. Al-Taani, Alaa Yehya, Dima Albals, Mervat Alsous   +3 more
doaj   +1 more source

Cocrystallization approach: Dissolution rate enhancement of carbamazepine with various coformers and virtual screening tools [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Cocrystallization is a promising solid-state modification used to enhance the dissolution rate and solubility of poorly water-soluble drugs, such as carbamazepine.
Taofik Rusdiana, Fitrianti Darusman, Iyan Sopyan, Silvi S. Putri   +3 more
doaj   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Evaluating a virtual paediatric adverse drug reaction clinic

British Journal of Clinical Pharmacology, EarlyView.
Aims Adverse drug reactions (ADRs) are a common problem in paediatric health care. There is limited access to expertise in the evaluation and management of potential ADRs in children, limiting access to these services and creating delays in assessment and management.
Emily Hauck, Blanca Del Pozzo‐Magana, Michael Rieder   +2 more
wiley   +1 more source

Severe Carbamazepine Toxicity Treated with Continuous Venovenous Hemofiltration at Palestine Medical Complex: Two Case Reports

International Medical Case Reports Journal, 2022
Mowaffaq A Nasif,1 Hiba H Falana,2 Heba KH Hamed,1 Qusai GH Yousef,3 Mohammad A Jaradat1 1Intensive Care Unit, Palestine Medical Complex, Ramallah, Palestine; 2Department of Pharmacy, Birzeit University, Ramallah, Palestine; 3Internal Medicine Department,
Nasif MA, Falana HH, Hamed HKH, Yousef QGH, Jaradat MA   +4 more
doaj  

Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors

British Journal of Clinical Pharmacology, EarlyView.
Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem, Mohannad N. AbuHaweeleh, Humam Emad Rajha, Mhd Osama Rahhal, Ahmad Hamdan, Lina Naseralallah   +5 more
wiley   +1 more source