Results 61 to 70 of about 83,313 (237)

Bioaccumulation and bioconcentration of carbamazepine and other pharmaceuticals in fish under field and controlled laboratory experiments. Evidences of carbamazepine metabolization by fish.

open access: yesScience of the Total Environment, 2016
There is a growing interest in evaluating the presence of pharmaceutical residues and their metabolites in aquatic biota. In this study, twenty pharmaceuticals, including carbamazepine (CBZ) and two metabolites, were analyzed in homogenates of two fish ...
M. Valdés   +6 more
semanticscholar   +1 more source

Identification of drug-specific public TCR driving severe cutaneous adverse reactions

open access: yesNature Communications, 2019
Severe cutaneous adverse reactions (SCAR) is a T cell-mediated, potentially lethal drug hypersensitivity (DH). Here, the authors identify a carbamazepine-specific TCR common among patients with carbamazepine-induced SCAR that confers SCAR-like pathology ...
Ren-You Pan   +17 more
doaj   +1 more source

Effects of carbamazepine on serum parathormone, 25-hydroxyvitamin D, bone specific alkaline phosphatase, C-telopeptide, and osteocalcin levels in healthy rats

open access: yes, 2012
It is still not completely clear whether carbamazepine causes alterations in vitamin D status and in bone metabolism. The objective of this study was to investigate the effects of carbamazepine on serum levels of 25-hydroxyvitamin D and on biomarkers of ...
KIR, HALE MARAL   +3 more
core  

Transformation of carbamazepine dihydrate to anhydrous carbamazepine [PDF]

open access: yes, 2015
An investigation of carbamazepine dihydrate transformation to anhydrous carbamazepine was presented. In this works, carbamazepine dihydrate and solvents (ethanol, methanol, propanol, acetonitrile, ethyl acetate and methyl acetate) were used.
Noraini, Ghazali
core  

Protective Effect of Wheat Germ Oil on Sex Hormones Disorders and Uterine Tissue Disorders Morphology Following Treatment with Carbamazepine in Epileptic Female Mice with Pentylenetetrazol [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2015
Background & Objective: Epilepsy is one of the common neurological diseases and carbamazepine is an antiepileptic drug that causes oxidative stress, endocrine and the reproductive system long term disorders.
Elham Ahmadi   +3 more
doaj  

The influence of CYP2C8*3 on carbamazepine serum concentration in epileptic pediatric patients

open access: yesBalkan Journal of Medical Genetics, 2016
The aim of the present study was to investigate the distribution of CYP2C8 variants *3 and *5, as well as their effect on carbamazepine pharmacokinetic properties, in 40 epileptic pediatric patients on carbamazepine treatment.
Milovanovic DD   +7 more
doaj   +1 more source

The interaction between carbamazepine and erythromycin

open access: yes, 1989
Erythromycin has been reported to interact with the anticonvulsant, carbamazepine, in both children and adults. Toxic serum levels of carbamazepine are observed within 24 h of antibiotic administration, suggesting a mechanism not previously described ...
Kenneth W. Renton, Patricia V. Turner
core   +1 more source

Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial

open access: yes, 2007
Objective: To compare the behavioural side effects associated with two commonly used antiepilepsy drugs--phenobarbital and carbamazepine--in children in Bangladesh. Design: Prospective randomised controlled single centre trial.
Neville, B.   +5 more
core  

Carbamazepine-induced hypogammaglobulinemia

open access: yes, 2012
Carbamazepine is used to control seizures. Its common side effects are sleep disorders, anorexia, nausea, vomiting, polydipsia, irritability, ataxia, and diplopia. Involvement of the immune system is rare, and few cases of decreased immunoglobulin levels
Eroglu, Saliha   +11 more
core   +1 more source

HLA-A★3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

open access: yesNew England Journal of Medicine, 2011
BACKGROUND Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopapular exanthema to severe blistering reactions. The HLA-B★1502 allele has been shown to be strongly correlated with carbamazepine-induced Stevens–Johnson ...
M. McCormack   +30 more
semanticscholar   +1 more source

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