Results 51 to 60 of about 4,935 (147)

Functional genomics of a symbiotic community : shared traits in the olive fruit fly gut microbiota [PDF]

open access: yes, 2019
The olive fruit fly Bactrocera oleae is a major pest of olives worldwide and houses a specialized gut microbiota dominated by the obligate symbiont “Candidatus Erwinia dacicola”. Ca. E. dacicola is thought to supplement dietary nitrogen to the host, with
Blow, F   +6 more
core   +2 more sources

Conversion of pyridoxal to pyridoxamine with NH3 and H2 on nickel generates a protometabolic nitrogen shuttle under serpentinizing conditions

open access: yesThe FEBS Journal, Volume 292, Issue 12, Page 3041-3055, June 2025.
Recent studies show that Ni0 catalyzes amino acid synthesis from 2‐oxoacids via reductive amination. We show that the cofactor pyridoxal is reductively aminated to pyridoxamine, the NH2‐transferring intermediate of transaminations, with NH3 (~ 5 mm) and H2 (5 bar) on Ni0 catalysts within hours in water under serpentinizing hydrothermal vent conditions (
Manon Laura Schlikker   +7 more
wiley   +1 more source

KEGG orthology-based annotation of the predicted proteome of Acropora digitifera: ZoophyteBase - an open access and searchable database of a coral genome [PDF]

open access: yes, 2013
BACKGROUND: Contemporary coral reef research has firmly established that a genomic approach is urgently needed to better understand the effects of anthropogenic environmental stress and global climate change on coral holobiont interactions.
Antonio Starcevic   +9 more
core   +2 more sources

How eriophyid mites shape metal metabolism in leaf galls on Tilia cordata

open access: yesNew Phytologist, Volume 246, Issue 5, Page 2222-2242, June 2025.
Summary Metal metabolism in plant–galler interactions is largely unknown. We hypothesise that the mites manipulate metal distribution by sequestration of excessive levels and differential regulation of metalloproteins to support the main functions of gall‐nutrition, protection and microenvironment.
Filis Morina   +8 more
wiley   +1 more source

Muscle carnosine metabolism and β-alanine supplementation in relation to exercise and training [PDF]

open access: yes, 2010
Carnosine is a dipeptide with a high concentration in mammalian skeletal muscle. It is synthesized by carnosine synthase from the amino acids L-histidine and beta-alanine, of which the latter is the rate-limiting precursor, and degraded by carnosinase ...
Baguet, Audrey   +3 more
core   +2 more sources

Regulation of Arginine Metabolism and Ethanol Tolerance in Saccharomyces cerevisiae by BTN2

open access: yesFood Science &Nutrition, Volume 13, Issue 5, May 2025.
The impact of BTN2 modified strains on key metabolites, enzymes, and gene expression in the arginine metabolic pathway was investigated. BTN2 knock out strain was found to reduce arginine uptake and promote arginine and urea degradation. BTN2 was found to enhance ethanol tolerance and reduce ethanol‐induced oxidative damage.
Ting Xia   +6 more
wiley   +1 more source

Biological Channeling of a Reactive Intermediate in the Bifunctional Enzyme DmpFG

open access: yes, 2016
It has been hypothesized that the bifunctional enzyme DmpFG channels its intermediate, acetaldehyde, from one active site to the next using a buried intermolecular channel identified in the crystal structure.
Attwood, Paul V.   +3 more
core   +1 more source

The problem of nitrogen disposal in the obese [PDF]

open access: yes, 2014
Amino-N is preserved because of the scarcity and nutritional importance of protein. Excretion requires its conversion to ammonia, later incorporated into urea.
Alemany, Marià, 1946-
core   +2 more sources

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

open access: yes, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana   +2 more
core   +2 more sources

Metabolic Dialogue Shapes Immune Response in the Tumor Microenvironment

open access: yesEuropean Journal of Immunology, Volume 55, Issue 4, April 2025.
Metabolic antagonism in the TME suppresses CD8+ T cell function by depleting essential nutrients and generating toxic byproducts. Metabolic symbiosis between tumor cells and TAMs fosters an immunosuppressive microenvironment. Disrupting metabolic interactions can overcome immune suppression, boost antitumor immunity, and enhance immunotherapy efficacy.
Fengxia Gao   +3 more
wiley   +1 more source

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