Functional genomics of a symbiotic community : shared traits in the olive fruit fly gut microbiota [PDF]
The olive fruit fly Bactrocera oleae is a major pest of olives worldwide and houses a specialized gut microbiota dominated by the obligate symbiont “Candidatus Erwinia dacicola”. Ca. E. dacicola is thought to supplement dietary nitrogen to the host, with
Blow, F +6 more
core +2 more sources
Recent studies show that Ni0 catalyzes amino acid synthesis from 2‐oxoacids via reductive amination. We show that the cofactor pyridoxal is reductively aminated to pyridoxamine, the NH2‐transferring intermediate of transaminations, with NH3 (~ 5 mm) and H2 (5 bar) on Ni0 catalysts within hours in water under serpentinizing hydrothermal vent conditions (
Manon Laura Schlikker +7 more
wiley +1 more source
KEGG orthology-based annotation of the predicted proteome of Acropora digitifera: ZoophyteBase - an open access and searchable database of a coral genome [PDF]
BACKGROUND: Contemporary coral reef research has firmly established that a genomic approach is urgently needed to better understand the effects of anthropogenic environmental stress and global climate change on coral holobiont interactions.
Antonio Starcevic +9 more
core +2 more sources
How eriophyid mites shape metal metabolism in leaf galls on Tilia cordata
Summary Metal metabolism in plant–galler interactions is largely unknown. We hypothesise that the mites manipulate metal distribution by sequestration of excessive levels and differential regulation of metalloproteins to support the main functions of gall‐nutrition, protection and microenvironment.
Filis Morina +8 more
wiley +1 more source
Muscle carnosine metabolism and β-alanine supplementation in relation to exercise and training [PDF]
Carnosine is a dipeptide with a high concentration in mammalian skeletal muscle. It is synthesized by carnosine synthase from the amino acids L-histidine and beta-alanine, of which the latter is the rate-limiting precursor, and degraded by carnosinase ...
Baguet, Audrey +3 more
core +2 more sources
Regulation of Arginine Metabolism and Ethanol Tolerance in Saccharomyces cerevisiae by BTN2
The impact of BTN2 modified strains on key metabolites, enzymes, and gene expression in the arginine metabolic pathway was investigated. BTN2 knock out strain was found to reduce arginine uptake and promote arginine and urea degradation. BTN2 was found to enhance ethanol tolerance and reduce ethanol‐induced oxidative damage.
Ting Xia +6 more
wiley +1 more source
Biological Channeling of a Reactive Intermediate in the Bifunctional Enzyme DmpFG
It has been hypothesized that the bifunctional enzyme DmpFG channels its intermediate, acetaldehyde, from one active site to the next using a buried intermolecular channel identified in the crystal structure.
Attwood, Paul V. +3 more
core +1 more source
The problem of nitrogen disposal in the obese [PDF]
Amino-N is preserved because of the scarcity and nutritional importance of protein. Excretion requires its conversion to ammonia, later incorporated into urea.
Alemany, Marià, 1946-
core +2 more sources
Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana +2 more
core +2 more sources
Metabolic Dialogue Shapes Immune Response in the Tumor Microenvironment
Metabolic antagonism in the TME suppresses CD8+ T cell function by depleting essential nutrients and generating toxic byproducts. Metabolic symbiosis between tumor cells and TAMs fosters an immunosuppressive microenvironment. Disrupting metabolic interactions can overcome immune suppression, boost antitumor immunity, and enhance immunotherapy efficacy.
Fengxia Gao +3 more
wiley +1 more source

