Results 111 to 120 of about 110,777 (250)

Environmental Dissemination of Multidrug‐Resistant Gram‐Negative Pathogens in Djibouti's Wastewaters

open access: yesPublic Health Challenges, Volume 4, Issue 4, December 2025.
ABSTRACT Background The occurrence of multidrug‐resistant (MDR) Enterobacteriaceae‐producing extended‐spectrum β‐lactamases (ESBLs) and/or carbapenemases is increasingly reported in clinical and environmental settings. Here, we aimed to investigate the resistance profile of gram‐negative bacterial isolates from urban and environmental wastewater in ...
Ayan Ali Ragueh   +4 more
wiley   +1 more source

Population-Based Pharmacokinetics and Dose Optimization of Imipenem in Vietnamese Critically-Ill Patients

open access: yesInfection and Drug Resistance, 2022
Thanh D Dinh,1,2 Hung N Nguyen,1 Ba Hai Le,1 Thuy TT Nguyen,1 Huong TL Nguyen1 1Department of Clinical Pharmacy, Hanoi University of Pharmacy, Hanoi, Vietnam; 2Phu Tho General Hospital, Việt Trì, Phu Tho Province, VietnamCorrespondence: Huong TL Nguyen ...
Dinh TD   +4 more
doaj  

Silver (I) and Silver (II) Oxide Films for Biomedical Implants: Synthesis, Stability, Ion Release, and Antibacterial Efficacy

open access: yesJournal of Biomedical Materials Research Part A, Volume 113, Issue 11, November 2025.
ABSTRACT Coatings of silver compounds with higher dissolution rates than metallic silver offer a promising approach for delivering Ag+ ions to prevent medical implant device‐associated infections. In this study, we investigate the synthesis and characterization of single‐phase, silver (I) oxide (Ag2O) and silver (II) oxide (AgO) for potential ...
Maxwell Akantibila   +12 more
wiley   +1 more source

Microbiologic Cure with a Simplified Dosage of Intravenous Colistin in Adults: A Retrospective Cohort Study

open access: yesInfection and Drug Resistance, 2023
Sulaiman A Al-Zubairy Clinical Pharmacy Services, Johns Hopkins Aramco Healthcare, Dhahran, SaudiCorrespondence: Sulaiman A Al-Zubairy, Johns Hopkins Aramco Healthcare, 6th St, Dhahran, 34465, Saudi, Tel +966 138706287, Email sulaiman.azlubairy@jhah ...
Al-Zubairy SA
doaj  

Antibiotic Resistance: A Genetic and Physiological Perspective

open access: yesMedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy   +9 more
wiley   +1 more source

Ertapenem-Induced Neurotoxicity: A Literature Review of Clinical Characteristics and Treatment Outcomes

open access: yesInfection and Drug Resistance, 2023
Chunjiang Wang,1 Yulu Zhou,2 Ya Zhou,3 Chao Ye4 1Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, People’s Republic of China; 2Department of Pharmacy, Hunan Provincial Maternal and Child Health Care ...
Wang C, Zhou Y, Zhou Y, Ye C
doaj  

Ligand binding Pro‐miscuity of acylpeptide hydrolase, structural analysis of a detoxifying serine hydrolase

open access: yesProtein Science, Volume 34, Issue 11, November 2025.
Abstract Acylpeptide hydrolase (APEH) or acylaminoacyl‐peptidase (AAP) is a serine hydrolase that regulates protein metabolism. It can also bind to and process unusual substrates, acting as a detoxifier. To better understand its promiscuous specificity, we determined the cryo‐EM structures of mammalian APEH complexed with classical serine protease ...
Anna J. Kiss‐Szemán   +8 more
wiley   +1 more source

COVID-19 and Listeria Meningitis Treated by Ampicillin, Sulfamethoxazole/Trimethoprim and Meropenem

open access: yesInfection and Drug Resistance, 2023
Masafumi Seki,1,* Haruka Karaushi,1,* Noriko Arai,2 Takeshi Hayashi,2 Kotaro Mitsutake1 1Division of Infectious Diseases and Infection Control, Saitama Medical University International Medical Center, Hidaka City, Saitama, Japan; 2Division of ...
Seki M   +4 more
doaj  

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