Results 121 to 130 of about 30,619 (237)

Bacterial Agents and Their Multidrug‐Resistance Profile Among Patients Suspected of Bacterial Infections in Hakim Gizaw Hospital, Debre Berhan, Ethiopia: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Antimicrobial resistance is a global threat. Bacteria showed higher resistance in Ethiopia, and up‐to‐date data on it is urgently required for effective interventions. This study aimed to determine occurrence of multi‐drug‐resistant (MDR) bacterial isolates among patients presented to Hakim Gizaw Hospital (HGH).
Tizazu Zenebe Zelelie   +8 more
wiley   +1 more source

Community-acquired pneumonia caused by carbapenem-resistant Streptococcus pneumoniae: re-examining its prevention and treatment

open access: yes, 2014
Asako Doi,1,2 Kentaro Iwata,3 Hiroshi Takegawa,4 Kanji Miki,5 Yumi Sono,1,2 Hiroaki Nishioka,2 Jumpei Takeshita,6 Keisuke Tomii,7 Tsunekazu Haruta11Department of Infectious Diseases, 2Department of General Internal Medicine, Kobe City Medical Center ...
Sono Y   +8 more
core  

Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC).

open access: yes, 2016
A non-haem iron and 2-oxoglutarate oxygenase, CarC catalyses the highly unusual epimerisation and desaturation of a (3S,5S)-carbapenam 2 to give a (5R)-carbapenem 1. All stereoisomers of 2 were synthesised and analysed as CarC substrates.

core   +1 more source

Microbiological Spectrum and Antimicrobial Resistance Patterns in Tubo‐Ovarian Abscesses Managed by Surgery or Drainage at a Tertiary Hospital in Vietnam: A Retrospective Case Series

open access: yesHealth Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Tubo‐ovarian abscess requires empirical antimicrobial therapy before culture results are available, but local antimicrobial resistance data are limited in Vietnam. We described the microbiological spectrum and antimicrobial susceptibility patterns of tubo‐ovarian abscesses managed by surgery or drainage.
Bui Chi Thuong   +2 more
wiley   +1 more source

Prediction of imipenem-resistant microorganisms among the nosocomial critically ill patients with Gram-negative bacilli septicemia: a simple risk score

open access: yesInfection and Drug Resistance, 2018
I-Ling Chen,1,2 Chen-Hsiang Lee,2–4 Shih-Wen Ting,2,3 Lily Yu-Chin Wang1 1Department of Pharmacy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; 2Infection Control Team, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan ...
Chen IL, Lee CH, Ting SW, Wang LY
doaj  

Liquid Biopsy: Past, Present, and Future

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu   +8 more
wiley   +1 more source

Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae of Sequence Type 36

open access: yes, 2018
Sequence type 36 (ST36) Klebsiella pneumoniae is distributed worldwide. We found an ST36 K. pneumoniae clinical isolate that was carbapenem resistant, carried bla KPC-2 ,
Zhiyong Zong   +3 more
core   +1 more source

Machine Learning–Augmented Precision Dosing: Integrating Pharmacokinetic Modeling With Clinical Decision Support

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 11, November 2026.
ABSTRACT Inter‐individual variability in drug exposure can lead to ineffective therapy or toxicity, particularly in vulnerable patients. Routine model‐informed precision dosing (MIPD) relies mainly on population pharmacokinetic (PopPK) models, Bayesian forecasting, and therapeutic drug monitoring (TDM).
Yunmeng Pang   +5 more
wiley   +1 more source

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