Results 121 to 130 of about 101,265 (243)

Metalloids: Semi as Metals yet Full of Antimicrobial Potential

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm, Muhammad Jawad Nasim, Claus Jacob   +2 more
wiley   +1 more source

In Silico Molecular Analysis of Carbapenemase-Negative Carbapenem-Resistant Pseudomonas aeruginosa Strains in Greece

Microorganisms
To date, three carbapenem resistance mechanisms have been identified: carbapenemase released from the pathogen, changes in the expression of the outer membrane OprD porin, and overexpression of the efflux pump MexAB-OprM.
Katerina Tsilipounidaki, Christos-Georgios Gkountinoudis, Zoi Florou, George C. Fthenakis, Efthymia Petinaki   +4 more
doaj   +1 more source

CLINICAL AND PHARMACOECONOMIC ANALYSIS OF CARBAPENEMS (MEROPENEM, IMIPENEM AND DORIPENEM) IN NOSOCOMIAL PNEUMONIA TREATMENT

Фармакоэкономика, 2015
the article presents the results of a retrospective study conducted in the period from 2008 to 2011 in Moscow’s hospitals. The aim of the study was to compare the clinical and pharmacoeconomical efficacy of carbapenems in nosocomial pneumonia treatment ...
I. I. Shteynberg, S. K. Zyryanov, Yu. B. Belousov   +2 more
doaj  

Carbapenem-Resistant Enterobacteriaceae Colonization or Infection Was Not Associated with Post-Liver Transplant Graft Failure: An Observational Cohort Study

GE: Portuguese Journal of Gastroenterology
Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) epidemiology among liver transplant (LT) recipients is variable. We studied the impact of CRE colonization and infection on LT recipients’ outcomes.
João Caria, Ana C. Gonçalves, Gonçalo Cristóvão, Maria Carlos, Sara Magalhães, Vasco Almeida, Fernanda Moreno, Élia Mateus, Hélder Pinheiro, Diana Póvoas, Fernando M.T. Maltez, Rui Perdigoto, Filipe S. Cardoso, Hugo P. Marques   +13 more
doaj   +1 more source

Double-carbapenem regimen, alone or in combination with colistin, in the treatment of infections caused by carbapenem-resistant Klebsiella pneumoniae (CR-Kp) [PDF]

, 2017
Aloj, F., Castaldi, D., D'Abramo, A., De Angelis, M., Gizzi, F., Mascellino, M. T., Mastroianni, C. M., Oliva, Alessandra, Scorzolini, L., Storto, M., Vullo, V.   +10 more
core   +1 more source

Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients. [PDF]

, 2016
This study aimed to investigate the pharmacokinetics (PK), safety, and tolerability of a single dose of ceftazidime-avibactam in pediatric patients. A phase I, multicenter, open-label PK study was conducted in pediatric patients hospitalized with an ...
Armstrong, Jon, Arrieta, Antonio, Bishai, Raafat, Bradley, John S, Das, Shampa, Delair, Shirley, Edeki, Timi, Holmes, William C, Li, Jianguo, Moffett, Kathryn S, Mukundan, Deepa, Perez, Norma, Romero, José R, Speicher, David, Sullivan, Janice E, Zhou, Diansong   +15 more
core  

Plasmid-borne mcr-1 and replicative transposition of episomal and chromosomal blaNDM-1, blaOXA-69, and blaOXA-23 carbapenemases in a clinical Acinetobacter baumannii isolate

mSystems
A multidrug-resistant clinical Acinetobacter baumannii isolate with resistance to most antibiotics was isolated from a patient at an intensive care unit. The genetic environment, transcriptome, mobile, and resistome were characterized.
Masego Mmatli, Nontombi Marylucy Mbelle, John Osei Sekyere   +2 more
doaj   +1 more source

Analysis of the Class 1 Integrons, Carbapenemase Genes and Biofilm Formation Genes Occurrence in Acinetobacter baumannii Clinical Isolates

Polish Journal of Microbiology
Acinetobacter baumannii is a non-fermentative Gram-negative bacterium that can cause nosocomial infections in critically ill patients. Carbapenem-resistant A. baumannii (CRAB) has spread rapidly in clinical settings and has become a key concern. The main
Xiu Yu, Dai Yueru, Yin Shasha, Wei Quhao
doaj   +1 more source

Analyzing Antibiotic Resistance in Bacteria from Wastewater in Pakistan Using Whole-Genome Sequencing

Antibiotics
Background: Wastewater is a major source of Antibiotic-Resistant Bacteria (ARB) and a hotspot for the exchange of Antibiotic-Resistant Genes (ARGs). The occurrence of Carbapenem-Resistant Bacteria (CRB) in wastewater samples is a major public health ...
Fazal Sattar, Xiao Hu, Anugrah Saxena, Kathy Mou, Huigang Shen, Hazrat Ali, Muhammad Afzal Ghauri, Yasra Sarwar, Aamir Ali, Ganwu Li   +9 more
doaj   +1 more source

Associations between Carbapenem Use, Carbapenem-Resistant Pseudomonas aeruginosa, and Carbapenem-Resistant Acinetobacter baumannii [PDF]

Infection Control & Hospital Epidemiology, 2013
Anucha, Apisarnthanarak, Sumana, Jitpokasem, Linda M, Mundy   +2 more
openaire   +2 more sources