Results 131 to 140 of about 75,516 (259)

Analyzing Antibiotic Resistance in Bacteria from Wastewater in Pakistan Using Whole-Genome Sequencing

open access: yesAntibiotics
Background: Wastewater is a major source of Antibiotic-Resistant Bacteria (ARB) and a hotspot for the exchange of Antibiotic-Resistant Genes (ARGs). The occurrence of Carbapenem-Resistant Bacteria (CRB) in wastewater samples is a major public health ...
Fazal Sattar   +9 more
doaj   +1 more source

Effects of Nacubactam and Its Metabolites on QTc Interval: A Pooled Analysis of Two Randomized Phase 1 Studies

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Nacubactam is a β‐lactamase inhibitor. Early‐phase studies with 1000/2000/4000/8000 mg nacubactam monotherapy were not powered to assess proarrhythmic risk. Therefore, this analysis pooled electrocardiogram data from two placebo‐controlled studies to quantify potential effects of nacubactam on cardiac repolarization.
Jun Morita, Sue McKendrick, Yuji Kumagai
wiley   +1 more source

Emergence of Tigecycline and Carbapenem-Resistant Citrobacter freundii Co-Carrying tmexCD1-toprJ1, blaKPC-2, and blaNDM-1 from a Sepsis Patient

open access: yes, 2023
Jinzhu Huang,* Jinxin Zhao,* Miao Yi, Yaling Yuan, Peiwen Xia, Bingxue Yang, Jiajia Liao, Zijun Dang, Yun Xia* Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ...
Liao J   +8 more
core  

Exploring the Antimicrobial Efficacy of Mesenchymal Stem Cell Secretome Against Klebsiella pneumoniae in Urinary Tract Infections

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Antimicrobial resistance (AMR) has become a global health crisis, with Klebsiella pneumoniae (K. pneumoniae) emerging as a major driver of AMR and a leading cause of urinary tract infections (UTIs). Mesenchymal stem cell (MSC)‐derived secretomes have gained attention for their antimicrobial properties.
Leen Ali   +3 more
wiley   +1 more source

Carbapenem Resistance in Animal-Environment-Food from Africa: A Systematic Review, Recommendations and Perspectives

open access: yes
Komla Mawunyo Dossouvi,1 Ayawovi Selom Ametepe2 1Department of Microbiology, DGlobal Health Research Institute, Lomé, Togo; 2Department of Biological Sciences, University of Arkansas, Fayetteville, Arkansas, USACorrespondence: Komla Mawunyo Dossouvi, Tel
Ametepe AS, Dossouvi KM
core  

First literature review of carbapenem-resistant Providencia

open access: yes, 2018
Providencia species are Gram-negative bacteria that belong to the Enterobacteriaceae family. They have intrinsic resistance to colistin and tigecycline, which makes treatment of the multidrug-resistant strains of Providencia challenging.
M. Abdallah, A. Balshi
core   +1 more source

Carbapenem-resistant and cephalosporin-susceptible Pseudomonas aeruginosa: a notable phenotype in patients with bacteremia

open access: yes, 2018
Shuang Li,1,* Xiaojiong Jia,1,* Congya Li,1 Hua Zou,1 Hang Liu,1 Yuanbiao Guo,2 Liping Zhang1 1Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; 2Medical Research Center, The Second ...
Zou H   +6 more
core  

Carbapenem susceptibilities and non-susceptibility concordance to different carbapenems amongst clinically important Gram-negative bacteria isolated from intensive care units in Taiwan: Results from the Surveillance of Multicentre Antimicrobial Resistance in Taiwan (SMART) in 2009

open access: yes, 2014
To investigate the in vitro susceptibilities to various carbapenems amongst clinical Gram-negative bacteria isolated from patients in intensive care units of ten major teaching hospitals in Taiwan in 2009, a survey was conducted to determine the minimum ...
Jean, Shio-Shin;Hsueh, Po-Ren;Lee, Wen-Sen;Yu, Kwok-Woon;Liao, Chun-Hsing;Chang, Feng-Yi;Ko, Wen-Chien;Wu, Jiunn-Jong;Chen, Yen-Hsu;Chen, Yao-Shen;Liu, Jien-Wei;Lu, Min-Chi;Liu, Cheng-Yi;Lam, Carlos;Chen, Ray-Jade   +1 more
core  

Virulence Factors and Carbapenem-Resistance Mechanisms in Hypervirulent Klebsiella Pneumoniae

open access: yes
Yiqun Liao,1 Junjie Gong,1 Xiaoliang Yuan,2 Xiaoling Wang,1 Yuanhong Huang,3 Xiaohong Chen1 1Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, People’s Republic of China; 2Department of Respiratory ...
Liao Y   +5 more
core  

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