Results 111 to 120 of about 75,516 (259)

Molecular characterization of carbapenem-resistant Gram-negative bacilli clinical isolates in Algeria

open access: yes, 2018
Nadjette Bourafa,1–3 Wafaa Chaalal,1,4 Sofiane Bakour,1 Rym Lalaoui,1 Nafissa Boutefnouchet,2 Seydina M Diene,1 Jean-Marc Rolain1 1Aix Marseille Universite, MEPHI, IHU-Mediterranee Infection, Marseille, France; 2Laboratoire de Microbiologie et ...
Bakour S   +6 more
core  

CLINICAL AND PHARMACOECONOMIC ANALYSIS OF CARBAPENEMS (MEROPENEM, IMIPENEM AND DORIPENEM) IN NOSOCOMIAL PNEUMONIA TREATMENT

open access: yesФармакоэкономика, 2015
the article presents the results of a retrospective study conducted in the period from 2008 to 2011 in Moscow’s hospitals. The aim of the study was to compare the clinical and pharmacoeconomical efficacy of carbapenems in nosocomial pneumonia treatment ...
I. I. Shteynberg   +2 more
doaj  

Computational design of a soluble mimic of the outer membrane LPS transport protein LptD suitable for screening of antibiotics

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Lipopolysaccharides (LPS) are the principal chemical component of the outer leaflet of Gram‐negative bacteria and constitute the first barrier of defense against foreign molecules. Inhibition of LPS transport presents a novel concept for antibiotic discovery, and components of the transport bridge are targets of antimicrobial peptides. LptD, a
Wenzhao Dai   +5 more
wiley   +1 more source

Molecular Epidemiology of Carbapenem-Resistant Pseudomonas Aeruginosa Carrying Metallo-H-Lactamase Genes in Taiwan

open access: yes, 2008
Seventy-two isolates of carbapenem-resistant Pseudomonas aeruginosa (CRPA ) collected through the Taiwan Surveillance of Antimicrobial Resistance ( TSAR) program in 2000 and 2002 were studied for carriage of metallo-h- lactamase (MBL), integrase genes ...
黃昱璁;張上淳;楊采菱;楊馥綺;王振泰   +1 more
core  

AEG‐AESPANC‐OPGE‐SIED‐SPG Ibero‐Latin American Guidelines on Acute Pancreatitis (iLATAM‐AP)

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Karina Cárdenas‐Jaén   +44 more
wiley   +1 more source

Estudo de isolados clínicos de Pseudomonas aeruginosa multirresistentes e produtores de metalo-ß-lactamases [PDF]

open access: yes, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2011Nas últimas duas décadas, índices crescentes de resistência têm minado a eficácia
Guarneri, Rômulo
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Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

open access: yesVIEW, Volume 7, Issue 3, June 2026.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang   +9 more
wiley   +1 more source

Carbapenem-Resistant Enterobacteriaceae Colonization or Infection Was Not Associated with Post-Liver Transplant Graft Failure: An Observational Cohort Study

open access: yesGE: Portuguese Journal of Gastroenterology
Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) epidemiology among liver transplant (LT) recipients is variable. We studied the impact of CRE colonization and infection on LT recipients’ outcomes.
João Caria   +13 more
doaj   +1 more source

Cefdinir binding to a class A β‐lactamase revealed by serial cryo‐crystallography

open access: yesActa Crystallographica Section D, Volume 82, Issue 6, Page 672-682, June 2026.
Serial cryo‐crystallography reveals the structure of the extended‐spectrum β‐lactamase CTX‐M‐14 in complex with the third‐generation cephalosporin antibiotic cefdinir.One of the most common resistance mechanisms against antibiotics employed by Gram‐negative bacteria involves the production of β‐lactamases, resulting in rapid hydrolysis of the ...
Gargi Gore   +4 more
wiley   +1 more source

A novel plasmid carrying carbapenem-resistant gene blaKPC-2 in Pseudomonas aeruginosa

open access: yes, 2019
Yan-Yan Hu, Qi Wang, Qiao-Ling Sun, Gong-Xiang Chen, Rong Zhang2nd Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaAbstract: A carbapenem-resistant Pseudomonas aeruginosa ...
Wang Q, Chen GX, Sun QL, Zhang R, Hu YY
core  

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