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Update on the epidemiology of carbapenemases in Latin America and the Caribbean
Disponible en: https://www.tandfonline.com/doi/abs/10.1080/14787210.2020.1813023Abstract Introduction: Carbapenemases are β-lactamases able to hydrolyze a wide range of β-lactam antibiotics, including carbapenems.
Tobias Manuel Appel +2 more
exaly +4 more sources
Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe
Plasmid-acquired carbapenemases in Enterobacteriaceae, which were first discovered in Europe in the 1990s, are now increasingly being identified at an alarming rate.
Rafael Canton +2 more
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Carbapenems (imipenem, meropenem, biapenem, ertapenem, and doripenem) are β-lactam antimicrobial agents. Because carbapenems have the broadest spectra among all β-lactams and are primarily used to treat infections by multi-resistant Gram-negative ...
Chang-Ro Lee +2 more
exaly +2 more sources
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Current methods for the identification of carbapenemases
Journal of Chemotherapy, 2016Detection of carbapenemases in clinical microbiology labs is a challenging issue. Comparison of the results of susceptibility testing with the breakpoint values of carbapenems is the first step in the screening of carbapenemase producers. To date, screening of carbapenemase-producing (CP) bacteria has been mostly performed by a selective medium ...
Abed Zahedi Bialvaei +2 more
exaly +3 more sources
Emerging carbapenemases: a global perspective
International Journal of Antimicrobial Agents, 2010The celestial rise in antibiotic resistance among Gram-negative bacteria has challenged both the scientific and pharmaceutical sectors. The hallmark of this general increase is the unbridled dissemination of carbapenem resistance genes, namely KPC, OXA and metallo-β-lactamase variants.
Timothy R Walsh
exaly +3 more sources

