Results 121 to 130 of about 52,330 (263)

Importance of appropriate initial antibiotic therapy and de-escalation in the treatment of nosocomial pneumonia

open access: yesEuropean Respiratory Review, 2007
Inappropriate initial antibiotic therapy in nosocomial pneumonia is associated with higher mortality, longer hospital stays and increased healthcare costs.
J. Rello
doaj  

The carbapenem family [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 1982
openaire   +2 more sources

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

open access: yes
American Journal of Hematology, Volume 101, Issue 10, Page 2672-2676, October 2026.
Elisa Buzzatti   +25 more
wiley   +1 more source

‘Knowledge, attitudes and practices’ survey of Austrian veterinarians' antibiotic use in clinical practice

open access: yesVeterinary Record, Volume 199, Issue 5, Page e250-e261, 5/12 September 2026.
Abstract Background Antimicrobial resistance (AMR) is a critical global health issue, with antimicrobial use (AMU) in veterinary medicine playing a relevant role in its emergence. This study aimed to evaluate the knowledge, attitudes and practices of Austrian veterinarians regarding AMU and AMR.
Clair L. Firth   +4 more
wiley   +1 more source

Resistance to carbapenems and colistin in enterobacteria from wastewaters

open access: yes, 2020
S obzirom da se karbapenemi koriste kao lijekovi posljednje linije obrane u liječenju infekcija uzrokovanih višestruko otpornim enterobakterijama, rastuća prevalencija enterobakterija otpornih na karbapeneme postaje sve veći problem na globalnoj razini.
Žuljević, Valentina
core  

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo   +6 more
wiley   +1 more source

Antibacterial and Antibiofilm Activity of a Chemically Characterized Cinnamomum verum Bark Methanolic Extract Against Multidrug‐Resistant Bacteria: Preliminary Antibiotic–Interaction Screening and Exploratory Molecular Docking

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The methanolic extract of Cinnamomum verum exhibited antibacterial and antibiofilm activities, enhanced the efficacy of conventional antibiotics against multidrug‐resistant bacteria, and showed favorable interactions with key bacterial targets in molecular docking analyses, supporting its potential as a natural antimicrobial adjuvant for combating ...
Hayet Edziri   +11 more
wiley   +1 more source

The oral penems and carbapenems

open access: yesClinical Microbiology Reviews
SUMMARY The penem and carbapenem antibiotics provide some of the broadest spectrum coverage available and generally should only be used when narrower options are unavailable. The majority of available carbapenems can only be administered parenterally, but two orally administered penems (faropenem and sulopenem) and one orally ...
Sena Sayood   +3 more
openaire   +2 more sources

Prevalence and mechanisms of decreased susceptibility to carbapenems in Klebsiella pneumoniae isolates

open access: yes, 2007
In this study, we examined the prevalence of and mechanisms of decreased susceptibility to either imipenem or meropenem in Klebsiella pneumoniae isolates. A total of 230 clinical isolates of K. pneumoniae were collected from 13 clinical laboratories from
이경원
core   +1 more source

Clean Synthesis of N‐4‐Alkylamino‐7‐chloroquinoline Cyclic Imides: Influence of Lipophilicity on Antibacterial and Ecotoxicological Properties

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
For series 2a–d, there appears to be optimal activity against Klebsiella pneumoniae when lipophilicity is intermediate (log P 2.64 for 2b). Similarly, for series 2e–g, activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus mutans also increases (log P 3.71 for 2f).
Agenor P. Luz‐Filho   +9 more
wiley   +1 more source

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