Results 141 to 150 of about 52,330 (263)

Structural Analysis of Carbapenems and β-Lactamase Resistance [PDF]

General Background: Carbapenem antibiotics represent a critical class of β-lactam agents widely used to manage severe infections caused by multidrug-resistant bacteria. Specific Background: Their unique structure—particularly the carbon substitution at C-
Sunaid, Hayder Kadhim
core  

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source

Focused Update to International Consensus Recommendations for the Use of Prolonged‐Infusion Beta‐Lactam Antibiotics Among Severely Ill Adult Patients: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 9, September 2026.
ABSTRACT In 2023, international consensus recommendations suggested the use of prolonged‐infusion beta‐lactam antibiotics over short‐infusion dosing in severely ill adult patients to improve mortality or clinical cure, although the certainty of evidence was very low. With the availability of several new randomized controlled trials (RCTs), this focused
Lisa T. Hong, Alireza FakhriRavari, Marta Ulldemolins, Jason A. Roberts, Robert A. Bonomo, Marc H. Scheetz, on behalf of the Prolonged‐Infusion Beta‐Lactam Consensus Panel, Jacinda C. Abdul‐Mutakabbir, Mohammad H. Alshaer, Matteo Bassetti, Robert A. Bonomo, Kevin J. Downes, Alireza FakhriRavari, Mark Gilchrist, Lisa T. Hong, Jason A. Roberts, Marc H. Scheetz, Thomas Tängdén, Marta Ulldemolins, David C. Young   +19 more
wiley   +1 more source

Isolation, Associated Factors and Antimicrobial Susceptibility Patterns of Salmonella spp. in Human Stool, Eggshell Swab and Feces of Egg‐Laying Hens in Mekelle and Southeast Zones of Tigrai, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Illustration of Possible Salmonella spp. Contamination Pathways among the Animal‐Food‐Human‐Environment Interface at the Poultry Farm Settings. Source: Author's illustration. ABSTRACT Background Salmonellosis is an important foodborne and zoonotic disease commonly related to the ingestion of poultry products contaminated with Salmonella spp. Although a
Atsebaha Gebrekidan Kahsay, Tsehaye Asmelash, Enquebaher Kassaye   +2 more
wiley   +1 more source

Antimicrobial Resistance Among Selected Zoonotic Bacteria: A Case Study of Tortoises and Birds at the Uganda Wildlife Conservation Education Centre

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study investigated antimicrobial resistance in birds and tortoises at the Uganda Wildlife Conservation Education Centre. Escherichia coli predominated in birds, whereas Salmonella enteritidis predominated in tortoises with resistance to sulphonamides detected.
Delilah Diana Namara, Paul Ssajjakambwe, Sarah Robinah Nakabuye, Vanessa Alyj Katabazi, Celsus Sente   +4 more
wiley   +1 more source

<i>In vitro</i> carbapenem activity in <i>Neisseria gonorrhoeae</i>. [PDF]

JAC Antimicrob Resist
Brousseau J, Braille A, Mainardis M, Meunier F, Mérimèche M, Caméléna F, Berçot B.   +6 more
europepmc   +1 more source

Characterisation of Haemolytic Uropathogenic Escherichia coli Isolated From Dogs and Cats

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
The present study characterises 51 canine and feline haemolytic E. coli isolates from urinary tract infections by a polyphasic approach, including susceptibility testing, CH‐clonotyping, and DNA microarrays. The majority of isolates belonged to phylogenetic group B2 and were classified as extraintestinal pathogenic E.
Sarah Büttner, Joachim Spergser, Olga Makarova, Michael P. Szostak, Adriana Cabal Rosel, Werner Ruppitsch, Sabine Schäfer‐Somi, Elke Müller, Sascha D. Braun, Stefan Monecke, Ralf Ehricht, Frank Künzel, Igor Loncaric   +12 more
wiley   +1 more source

Prevalence and Genomic Characterization of mcr‐Positive Enterobacteriaceae in Retail Meat in Thailand Following the Colistin Ban

Microbiology and Immunology, Volume 70, Issue 9, Page 402-415, September 2026.
ABSTRACT This study aimed to investigate the prevalence and characteristics of mcr‐positive Enterobacteriaceae in retail meat in Thailand following the national ban on prophylactic colistin use in food producing animals. A total of 152 meat samples (103 chicken and 49 pork) were collected from supermarkets and open markets between July and September ...
Ahmed Abououf, Sharda Prasad Awasthi, Asmaa M. Elbastawesy, Noritoshi Hatanaka, Atsushi Hinenoya, Srinuan Somroop, Yukihiro Kaneko, Shinji Yamasaki   +7 more
wiley   +1 more source

Detection of carbapenem resistance mechanisms in difficult-to-treat Pseudomonas aeruginosa clinical isolates from a tertiary care hospital in Egypt. [PDF]

BMC Microbiol
Salem D, Zaiton M, El-Shenawy A, Dahroug H, El-Dein S, Gamal D, Althoqapy AA, Mohamed AA, Shemis MA, Diab M, Maklad SS.   +10 more
europepmc   +1 more source

A Lytic Bacteriophage Cocktail Attenuates Carbapenem‐Resistant Klebsiella pneumoniae–Acinetobacter baumannii Mixed‐Species Biofilms and Reshapes Transcriptional Responses

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
A lytic phage cocktail targeting CRKP–CRAB mixed biofilms was systematically evaluated through in vitro, device‐associated, and in vivo models. Integrated transcriptomic analysis revealed molecular responses underlying biofilm disruption, providing mechanistic insights and experimental evidence supporting phage cocktails as a promising strategy against
Xuefang Ren, Rui Zhu, Yijiang Yang, Xiaojuan You, Liuxiang Wang, Guangyu Fu, Yehuan Zheng, Chunxia Wang, Zhentao Wang, Yongwei Li   +9 more
wiley   +1 more source