Results 151 to 160 of about 40,327 (214)

Therapeutic strategies for multi-resistant <i>Escherichia coli</i> in urinary tract infections-a cause for concern. [PDF]

JAC Antimicrob Resist
Unni R, Varghese R, Arakal B, Padmanabhan L, Karmakar S, Sampathila A, Dalvi YB, Livingstone P.   +7 more
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Carbapenems

Journal of Chemotherapy, 2013
To assess the relative strengths and weaknesses of carbapenems by considering their microbiological, clinical, pharmacokinetics and pharmacokinetic/pharmacodynamic (PK/PD) properties and defining optimal conditions of uses of the new generation of carbapenems.Literature review.Except for ertapenem, the spectrum of activity is similar for all ...
Emmanuel Boselli, Bernard Allaouchiche
exaly   +3 more sources

Carbapenems in Pediatrics

Therapeutic Drug Monitoring, 2003
Antimicrobial resistance is increasing among bacterial pathogens. In particular, organisms producing extended spectrum beta-lactamase enzymes (ESBLs) and AmpC chromosomal beta-lactamase enzymes are resistant to third generation cephalosporins and pose a formidable challenge in the management of seriously ill patients.
Kassa, Ayalew, Sumati, Nambiar, Yuliya, Yasinskaya, Barbara A, Jantausch   +3 more
openaire   +2 more sources

Cephalosporins to carbapenems: 1-oxygenated carbapenems and carbapenams

Journal of Medicinal Chemistry, 1990
The photo "Wolff" rearrangement of readily available 2-diazoceph-3-em oxides (1) directly affords carbapen-2-ems, allowing a facile entry into a ring system previously accessible only by total synthesis, lengthly semisynthesis or fermentation. The chirality of the cephalosporin is accurately translated into the corresponding carbapenem. The resulting 1-
R L, Rosati, L V, Kapili, P, Morrissey, J A, Retsema   +3 more
openaire   +2 more sources