Results 61 to 70 of about 2,756 (235)
Electrocyclisations for Synthesis of Carbazoles and their Annulated Compounds
, 1994 Meiji College of Pharmacy, 1-35-23, Nozawa, Setagaya-ku, Tokyo 154, Japan Manuscript received 26 November 1993 The thermal- and photo-induced electrocydisations of the hexatriene systems involving indole nucleus for synthesis of the pharmacologically ...
TOMOMI KAWASAKI, MASANORI SAKAMOTO
core +1 more source
Advanced Science, EarlyView.Oxygen plasma functionalizes porous polyethylene, enabling complete hydrocarbon ionomer infiltration within a dense submicron pore network. The resulting reinforced composite membrane simultaneously enhances mechanical robustness and suppresses hydrogen permeation at ultrathin thickness. An integrated performance index confirms the effectiveness of the
Sungjun Kim +6 more
wiley +1 more source
Direct asymmetric N-propargylation of indoles and carbazoles catalyzed by lithium SPINOL phosphate
Nature Communications, 2020 Asymmetric functionalization of N–H bonds constitutes an important but less developed class of reactions. Here, the authors report the asymmetric direct N-propargylation of indoles and carbazoles with a lithium SPINOL phosphate as the chiral catalyst and
Yingcheng Wang +3 more
doaj +1 more source
Characterization and Biological Potency of Mono- to Tetra-Halogenated Carbazoles
, 2015 This paper deals with the characterization and aryl hydrocarbon receptor (AhR) agonist activities of a series of chlorinated, brominated, and mixed bromo/chlorocarbazoles, some of which have been identified in various environmental samples.
Nicole Riddell (1541164) +12 more
core +1 more source
Advanced Science, EarlyView.Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu +6 more
wiley +1 more source
Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity
Molecules, 2018 Background: Despite the progress achieved by anti-retroviral drug research in the last decades, the discovery of novel compounds endowed with selective antiviral activity and reduced side effects is still a necessity.
Carmela Saturnino +8 more
doaj +1 more source
Advanced Science, EarlyView.Stable water‐soluble luminescent tris(2,4,6‐trichlorophenyl)methyl (TTM) radicals, TTM‐trisTP3B and TTM‐trisTP9B, were designed and successfully synthesized. They exhibited deep‐red emissions and high photostability in water. TTM‐trisTP3B exhibited dual functionality as a fluorescence imaging (FI) probe and a magnetic resonance imaging (MRI) contrast ...
Kosuke Anraku +6 more
wiley +1 more source
Carbazole scaffolds in cancer therapy: a review from 2012 to 2018
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 For over half a century, the carbazole skeleton has been the key structural motif of many biologically active compounds including natural and synthetic products.
Samar Issa +6 more
doaj +1 more source
, 2007 135-140Treatment of 1-oxo-2-hydroxymethylene-1,2,3,4- tetrahydrocarbazole 1 with hydrazine hydrate, hydroxylamine hydrochloride, urea and thiourea in the presence of gl. acetic acid afforded the novel carbazole derivatives namely 4,5-dihydro-2H-pyrazino [
Sangeetha, V +3 more
core +1 more source
Advanced Science, EarlyView.Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang +11 more
wiley +1 more source