Results 51 to 60 of about 999 (168)

Increased TSLP and oxidative stress reflect airway epithelium injury upon cigarette smoke exposure. Is there a role for carbocysteine? [PDF]

Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammatory degenerative disease. Disease exacerbations accelerate lung function deterioration. Airway epithelium has a central role in COPD pathophysiology.
Ferraro, Maria, Patella, Bernardo, Moukri, Nadia, Inguanta, Rosalinda, Pinto, Paola, Donzì, Daniele, Bruno, Maria Giuseppina, Di Vincenzo, Serena, Lazzara, Valentina, Pace, Elisabetta   +9 more
core   +1 more source

Ambient ionisation mass spectrometry for drug and toxin analysis: A review of the recent literature

Drug Testing and Analysis, Volume 16, Issue 11, Page 1323-1344, November 2024.
Ambient ionization mass spectrometry enables the rapid, real‐time analysis of samples in their native state. This review highlights recent developments in the use of ambient ionization for drugs analysis across various fields, including forensics, anti‐doping, food safety, pharmaceuticals, environmental sciences, and diagnostic testing.
Alisha Henderson, Liam M. Heaney, Stephanie Rankin‐Turner   +2 more
wiley   +1 more source

Evaluation of the Effects of a Cosmetic Cream on Irritant Contact Dermatitis: Results of a Multicentre Open Trial

European Journal of Inflammation, 2003
The symptoms of irritant contact dermatitis (ICD) are often controlled by topical corticosteroids, which, however, are not suitable for the long-term management owing to the risk of side effects.
N. Cassano, C. Foti, S. Centofanti, L. Del Brocco, L. Donato, A. Ferrari, A. Bandiera, V. Colella, V. D'Argento, G. Di Pierro, G. Giglio, M. Mastrolonardo, V. Marzocca, V. Pietrantonio, G. Schiraldi, L. Ottomano, A. Pugliese, G.A. Vena   +17 more
doaj   +1 more source

Effect of Penetration Enhancers on Drug Nail Permeability from Cyclodextrin/Poloxamer-Soluble Polypseudorotaxane-Based Nail Lacquers

Pharmaceutics, 2018
Nail delivery has interest for local treatment of nail diseases. Nevertheless, the low permeability of drugs in the nail plaque precludes the efficacy of local treatments.
Elena Cutrín-Gómez, Soledad Anguiano-Igea, M. Begoña Delgado-Charro, José Luis Gómez-Amoza, Francisco J. Otero-Espinar   +4 more
doaj   +1 more source

Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series

Journal of Cachexia, Sarcopenia and Muscle, Volume 15, Issue 2, Page 513-535, April 2024.
Abstract There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when comparing interventions and their clinical value. The aim of this systematic review was to summarize and evaluate endpoints used to assess appetite and dietary intake in cancer cachexia clinical trials.
Ola Magne Vagnildhaug, Trude R. Balstad, Inger Ottestad, Asta Bye, Christine Greil, Jann Arends, Vickie Baracos, Leo R. Brown, Olav F. Dajani, Ross D. Dolan, Marie Fallon, Eilidh Fraser, Aleksandra Grzyb, Marianne J. Hjermstad, Gunnhild Jakobsen, Stein Kaasa, James McDonald, Iain Philips, Judith Sayers, Melanie R. Simpson, Mariana S. Sousa, Richard J.E. Skipworth, Barry J.A. Laird, Tora S. Solheim, on behalf of the Cancer Cachexia Endpoints Working Group   +24 more
wiley   +1 more source

Carbocysteine counteracts the effects of cigarette smoke on cell growth and on the SIRT1/FoxO3 axis in bronchial epithelial cells

, 2016
Background: Cigarette smoke may accelerate cellular senescence by increasing oxidative stress. Altered proliferation and altered expression of anti-aging factors, including SIRT1 and FoxO3, characterise cellular senescence.
Ferraro, M., BONSIGNORE, Maria Rosaria, Gjomarkaj, M., DI VINCENZO, Serena, BATTAGLIA, Salvatore, Dino, P., Saibene, F., Lanata, L., Pace, E., Bruno, A., Ferraro M, Battaglia S, Bruno A, Bonsignore M R, Pace E, Dino P, Saibene F, Lanata L, Gjomarkaj M, Di Vincenzo S   +19 more
core   +1 more source

Review: Antioxidant therapeutic advances in COPD

Therapeutic Advances in Respiratory Disease, 2008
Chronic obstructive pulmonary disease (COPD) is associated with a high incidence of morbidity and mortality. Cigarette smoke-induced oxidative stress is intimately associated with the progression and exacerbation of COPD and therefore targeting oxidative
Irfan Rahman
doaj   +1 more source

[The role of carbocystein in the treatment of sinusitis].

Otolaryngologia polska = The Polish otolaryngology, 2013
Chronic sinusitis is one of the most common presenting complaints of all doctor visits in the United States and Europe, with more than 13% of people affected in any given year. This disease has a wide range of impact on communities. Patients with recurrent or chronic sinusitis report a deteriorative sense of general health and vitality, when compared ...
Piotr, Dąbrowski, Małgorzata, Leszczyńska, Daniela, Mielcarek-Kuchta   +2 more
openaire   +1 more source

Carbocysteine in the Management of Stable COPD: Are Its Antioxidant and Anti-Inflammatory Properties Clinically Relevant?

, 2017
BACKGROUND: The recent epidemiological and experimental evidence suggest possible antioxidant effect of carbocysteine in patients with chronic obstructive pulmonary disease (COPD).AIM: To assess efficacy and tolerability of carbocysteine in the ...
Minov, Jordan, Vasilevska, Kristin, Atanasovska, Aneta, Petrova, Tatjana, Mijakoski, Dragan, Dragan Mijakoski, Jordan Minov, Saso Stoleski, Jovanka Karadzinska-Bislimovska, Stoleski, Sasho, Kristin Vasilevska, Tatjana Petrova, Aneta Atanasovska, Karadzinska-bislimovska, Jovanka   +13 more
core   +2 more sources

Mucoactive therapy in COPD

European Respiratory Review, 2010
It has been shown that mucus hypersecretion is associated with greater susceptibility for chronic obstructive pulmonary disease (COPD), excess forced expiratory volume in 1 s decline, hospitalisations and excess mortality. The effects of mucoactive drugs
M. Decramer, W. Janssens
doaj