Results 41 to 50 of about 853,705 (361)
Journal of Nanobiotechnology, 2023 Background Congenital disorders of glycosylation (CDGs) are genetic diseases caused by gene defects in glycan biosynthesis pathways, and there is an increasing number of patients diagnosed with CDGs.
Ji-Xiang Jia +6 more
doaj +1 more source
Construction of Multiscale Genome-Scale Metabolic Models: Frameworks and Challenges
Biomolecules, 2022 Genome-scale metabolic models (GEMs) are effective tools for metabolic engineering and have been widely used to guide cell metabolic regulation. However, the single gene–protein-reaction data type in GEMs limits the understanding of biological complexity.
Xinyu Bi +5 more
doaj +1 more source
Carbohydrate-binding modules: fine-tuning polysaccharide recognition.
Biochemical Journal, 2004 The enzymic degradation of insoluble polysaccharides is one of the most important reactions on earth. Despite this, glycoside hydrolases attack such polysaccharides relatively inefficiently as their target glycosidic bonds are often inaccessible to the ...
A. Boraston +3 more
semanticscholar +1 more source
Frontiers in Chemistry, 2022 The biochemical properties of α-1,3-galactosyltransferase WciN from Streptococcus pneumoniae serotype 6B were systemically characterized with the chemically synthesized Glcα-PP-(CH2)11-OPh as an acceptor substrate.
Wei Gong +14 more
doaj +1 more source
Nutrition reviews, 2020 Carbohydrates are increasingly being implicated in the epidemics of obesity, diabetes, and their downstream cardiometabolic diseases. The "carbohydrate-insulin model" has been proposed to explain this role of carbohydrates.
J. Sievenpiper
semanticscholar +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Dynamics of 5-hydroxymethylfurfural formation in shortbreads during thermal processing
Czech Journal of Food Sciences, 2013 The analysis was carried out of 5-hydroxymethyl-2-furfural (HMF) formation during the baking of shortbreads. The investigation was done on three types of shortbread in which sucrose, glucose, or fructose were used as sweeteners.
Stanisław KOWALSKI +3 more
doaj +1 more source
Analysis of acid-tolerance mechanism based on membrane microdomains in Saccharomyces cerevisiae
Microbial Cell Factories, 2023 Background Saccharomyces cerevisiae has been used in the biosynthesis of acid products such as organic acids owing to its acid tolerance. Improving the acid tolerance of S. cerevisiae is beneficial for expanding its application range.
Xueqin Lv +9 more
doaj +1 more source
A critical review on the analysis of lignin carbohydrate bonds
Green Chemistry, 2019 This review highlights the challenges of analyzing lignin–carbohydrate bonds, which are hypothesized to contribute to the recalcitrance in biomass fractionation.
Nicola Giummarella +3 more
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source