Results 41 to 50 of about 1,149,598 (340)

Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function

Nature Communications, 2022
Matriglycan, a repeating disaccharide on α-dystroglycan, is the receptor for Lassa virus and specific extracellular matrix proteins. Here, the authors demonstrate that matriglycan, in a length-dependent tunable manner, is both necessary and sufficient ...
M. Osman Sheikh, Chantelle J. Capicciotti, Lin Liu, Jeremy Praissman, Dahai Ding, Daniel G. Mead, Melinda A. Brindley, Tobias Willer, Kevin P. Campbell, Kelley W. Moremen, Lance Wells, Geert-Jan Boons   +11 more
doaj   +1 more source

Serum N-Glycome Diversity in Teleost and Chondrostrean Fishes

Frontiers in Molecular Biosciences, 2021
Recent advances in carbohydrate chemistry, chemical biology, and mass spectrometric techniques have opened the door to rapid progress in uncovering the function and diversity of glycan structures associated with human health and disease. These strategies
Kazuhiro Aoki, Tadahiro Kumagai, Tadahiro Kumagai, René Ranzinger, Carl Bergmann, Alvin Camus, Michael Tiemeyer   +6 more
doaj   +1 more source

Crystal Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with a Sulfated Carbohydrate Ligand [PDF]

, 2000
The macrophage and epithelial cell mannose receptor (MR) binds carbohydrates on foreign and host molecules. Two portions of MR recognize carbohydrates: tandemly arranged C-type lectin domains facilitate carbohydrate-dependent macrophage uptake of ...
Bjorkman, Pamela J., Chirino, Arthur J., Feizi, Ten, Leteux, Christine, Liu, Yang, Misulovin, Ziva, Nussenzweig, Michel C.   +6 more
core   +2 more sources

Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]

, 1998
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Bosbach, R., Brinck, U., Gabius, Hans-Joachim, Korabiowska, M.   +3 more
core   +1 more source

Engineered Microbial Cell Factories for Sustainable Production of L-Lactic Acid: A Critical Review

Fermentation, 2022
With the increasing demand for the biodegradable polymer material polylactic acid and its advantage of being metabolized by the human body, L-lactic acid (L-LA) is becoming increasingly attractive in environmental protection and food industry ...
Tiantian Liu, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu   +6 more
doaj   +1 more source

Application of NIR analysis to verify cocoa powder authenticity

Czech Journal of Food Sciences, 2004
At the present time the use of reliable control methods to ensure the labeled quality of food is task for organizations that have to limit or eliminate the falsification.
A. Trilčová, J. Čopíková, M. A Coimbra, A. Barros, L. Egert, A. Synytsya, H. Křístková   +6 more
doaj   +1 more source

Combinatorial Metabolic Engineering and Enzymatic Catalysis Enable Efficient Production of Colanic Acid

Microorganisms, 2022
Colanic acid can promote the lifespan of humans by regulating mitochondrial homeostasis, and it has widespread applications in the field of health. However, colanic acid is produced at a low temperature (20 °C) with low titer. Using Escherichia coli K-12
Suwei Li, Xianhao Xu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu   +6 more
doaj   +1 more source

Low-carbohydrate diets affect energy balance and fuel homeostasis differentially in lean and obese rats [PDF]

, 2006
In parallel with increased prevalence of overweight people in affluent societies are individuals trying to lose weight, often using low-carbohydrate diets.
Dijk, G. van,, Morens, C.,, Scheurink, A.J.W.,, Sirot, V.,   +3 more
core   +4 more sources

Combinatorial pathway enzyme engineering and host engineering overcomes pyruvate overflow and enhances overproduction of N-acetylglucosamine in Bacillus subtilis

Microbial Cell Factories, 2019
Background Glucosamine-6-phosphate N-acetyltransferase (GNA1) is the key enzyme that causes overproduction of N-acetylglucosamine in Bacillus subtilis.
Wenlong Ma, Yanfeng Liu, Xueqin Lv, Jianghua Li, Guocheng Du, Long Liu   +5 more
doaj   +1 more source

Dermatan Sulfate: Structure, Biosynthesis, and Biological Roles

Biomolecules
Dermatan sulfate (DS) is a remarkably versatile glycosaminoglycan that plays critical roles across a wide array of biological processes. Its unique structure, characterized by repeating disaccharide units of N-acetyl-D-galactosamine (GalNAc) and Iduronic
Congcong Chen, Xuyang Zhang, Weiting Zhang, Dahai Ding, Ravi Sankar Loka, Kun Zhao, Peixue Ling, Shuaishuai Wang   +7 more
doaj   +1 more source