Results 41 to 50 of about 1,129,100 (338)
Dermatan Sulfate: Structure, Biosynthesis, and Biological Roles
BiomoleculesDermatan sulfate (DS) is a remarkably versatile glycosaminoglycan that plays critical roles across a wide array of biological processes. Its unique structure, characterized by repeating disaccharide units of N-acetyl-D-galactosamine (GalNAc) and Iduronic
Congcong Chen +7 more
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Construction of Multiscale Genome-Scale Metabolic Models: Frameworks and Challenges
Biomolecules, 2022 Genome-scale metabolic models (GEMs) are effective tools for metabolic engineering and have been widely used to guide cell metabolic regulation. However, the single gene–protein-reaction data type in GEMs limits the understanding of biological complexity.
Xinyu Bi +5 more
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From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Microbial Cell Factories, 2021 Background Owing to the excellent properties of photosensitization, cercosporin, one of naturally occurring perylenequinonoid pigments, has been widely used in photodynamic therapy, or as an antimicrobial agent and an organophotocatalyst.
Tingan Zhou +7 more
doaj +1 more source
Metabolic Engineering of Saccharomyces cerevisiae for Efficient Retinol Synthesis
Journal of Fungi, 2023 Retinol, the main active form of vitamin A, plays a role in maintaining vision, immune function, growth, and development. It also inhibits tumor growth and alleviates anemia.
Xuan Wang +7 more
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Linoleic acid intake, plasma cholesterol and 10-year incidence of CHD in 20.000 middle-aged men and women in the Netherlands [PDF]
, 2012 We studied the associations of a difference in linoleic acid or carbohydrate intake with plasma cholesterol levels and risk of CHD in a prospective cohort study in the Netherlands. Data on diet (FFQ) and plasma total and HDL-cholesterol were available at
Boer, J.M.A. +4 more
core +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Dynamics of 5-hydroxymethylfurfural formation in shortbreads during thermal processing
Czech Journal of Food Sciences, 2013 The analysis was carried out of 5-hydroxymethyl-2-furfural (HMF) formation during the baking of shortbreads. The investigation was done on three types of shortbread in which sucrose, glucose, or fructose were used as sweeteners.
Stanisław KOWALSKI +3 more
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Journal of Nanobiotechnology, 2023 Background Congenital disorders of glycosylation (CDGs) are genetic diseases caused by gene defects in glycan biosynthesis pathways, and there is an increasing number of patients diagnosed with CDGs.
Ji-Xiang Jia +6 more
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