Results 91 to 100 of about 463,419 (290)

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Highly sensitive and selective sugar detection by terahertz nano-antennas [PDF]

open access: yesarXiv, 2015
Molecular recognition and discrimination of carbohydrates are important because carbohydrates perform essential roles in most living organisms for energy metabolism and cell-to-cell communication. Nevertheless, it is difficult to identify or distinguish various carbohydrate molecules owing to the lack of a significant distinction in the physical or ...
arxiv  

Carbohydrates in hot water extracts of soil aggregates as affected by long-term management [PDF]

open access: yes, 2002
Microbial carbohydrates are immediate by-products of microbial metabolism and play an important role in the formation and stabilization of soil structure.
Cheshire M.V.   +5 more
core   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Draft Genome Sequences of Salmonella enterica Serovar Typhimurium LT2 with Deleted Chitinases That Are Emerging Virulence Factors. [PDF]

open access: yes, 2017
Chitinases are glycosyl hydrolases that catalyze the hydrolysis of the β-1,4 linkages in complex carbohydrates and those that contain GlcNAc. These enzymes are considered emerging virulence factors during infection because the host glycan changes.
Arabyan, Narine   +2 more
core   +1 more source

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

open access: yesMolecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns   +4 more
wiley   +1 more source

Efficient, rapid one-electron photooxidation of chemisorbed polyhydroxyl alcohols and carbohydrates by TiO2 nanoparticles in an aqueous solution [PDF]

open access: yesarXiv, 2004
Time-resolved transient absorption spectroscopy has been used to study nanosecond and sub-microsecond electron dynamics in aqueous anatase nanoparticles in the presence of hole scavengers: chemisorbed polyols and carbohydrates. These polyhydroxylated compounds are rapidly oxidized by the holes; 50-60% of these holes are scavenged within the duration of
arxiv  

Carbohydrate Consumption and Fatigue: A Review

open access: yes, 2012
Fatigue is a condition that negatively impacts quality of life and occurs in about twenty four percent of adults worldwide. Many factors may contribute to fatigue.
Pharr, Jennifer R.
core  

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

open access: yesFEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee   +5 more
wiley   +1 more source

Determination of carbohydrates in infant milk powders by ultra-performance liquid chromatography with evaporative light scattering detector and BEH HILIC column [PDF]

open access: yesarXiv, 2017
The possibility of carbohydrate separation in BEH HILIC (Ethylene Bridged Hybride, Hydrophilic Interaction Liquid Chromatography) column was studied by ultra-performance liquid chromatography (UPLC) with evaporative light scattering detector (ELSD) and mobile phase containing amine compounds as modifiers.
arxiv  

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