Results 1 to 10 of about 999,343 (297)

Examining the Effects of the Nitrogen Environment on Growth and N2-Fixation of Endophytic Herbaspirillum seropedicae in Maize Seedlings by Applying 11C Radiotracing

open access: yesMicroorganisms, 2021
Herbaspirillum seropedicae, as an endophyte and prolific root colonizer of numerous cereal crops, occupies an important ecological niche in agriculture because of its ability to promote plant growth and potentially improve crop yield.
Spenser Waller   +8 more
doaj   +1 more source

On the Road towards Small-Molecule Programmed Cell Death 1 Ligand 1 Positron Emission Tomography Tracers: A Ligand-Based Drug Design Approach

open access: yesPharmaceuticals, 2023
PD-1/PD-L1 immune checkpoint blockade for cancer therapy showed promising results in clinical studies. Further endeavors are required to enhance patient stratification, as, at present, only a small portion of patients with PD-L1-positive tumors (as ...
Karsten Bamminger   +7 more
doaj   +1 more source

A Study On The Metal Carbide Composite Diffusion Bonding For Mechanical Seal

open access: yesArchives of Metallurgy and Materials, 2015
Mechanical Seal use highly efficient alternative water having a great quantity of an aqueous solution and has an advantage no corrosion brine. Metal Carbide composites have been investigated as potential materials for high temperature structural ...
Kim D.-K.   +7 more
doaj   +1 more source

Cu-Expanded Graphite Composite Material Preparation and Thermal Properties

open access: yesEurasian Chemico-Technological Journal, 2017
A composite material based on expanded graphite (EG) and copper compounds was obtained by natural graphite oxidation with 95% nitric acid, copper (II) nitrate and granular carbamide addition with further rapid heat treatment at three different ...
I. M. Karzov   +4 more
doaj   +1 more source

Recent Advances in the Development and Application of Radiolabeled Kinase Inhibitors for PET Imaging

open access: yesMolecules, 2015
Over the last 20 years, intensive investigation and multiple clinical successes targeting protein kinases, mostly for cancer treatment, have identified small molecule kinase inhibitors as a prominent therapeutic class.
Vadim Bernard-Gauthier   +3 more
doaj   +1 more source

E-Cigarette Aerosol Deposition and Disposition of [11C]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using Two Different Nicotine Formulations

open access: yesPharmaceuticals, 2022
Smoking is a cause of serious disease in smokers. Electronic cigarettes, delivering aerosolized nicotine, offer adult smokers a potentially less harmful alternative to combustible cigarettes.
Anders Wall   +9 more
doaj   +1 more source

Boron Nitride Nanotube Cyclotron Targets for Recoil Escape Production of Carbon-11

open access: yesInstruments, 2019
Boron nitride nanotubes (BNNTs) were investigated as a target media for cyclotron production of 11C for incident beam energy at or below 11 MeV. Both the 11B(p,n)11C and 14N(p,α)11C nuclear reactions were utilized.
Johanna Peeples   +5 more
doaj   +1 more source

Radiosynthesis and First Preclinical Evaluation of the Novel 11C-Labeled FAP Inhibitor 11C-FAPI: A Comparative Study of 11C-FAPIs and (68Ga) Ga-DOTA-FAPI-04 in a High–FAP-Expression Mouse Model

open access: yesFrontiers in Chemistry, 2022
Purpose: 68Ga-labeled fibroblast activation protein inhibitors, such as [68Ga]Ga-DOTA-FAPI-04 and [68Ga]Ga-DOTA-FAPI-46, have been successfully applied in positron emission tomography imaging of various tumor types.
Cheng Wang   +9 more
doaj   +1 more source

Preliminary Evaluations of [11C]Verubulin: Implications for Microtubule Imaging With PET

open access: yesFrontiers in Neuroscience, 2021
[11C]Verubulin (a.k.a.[11C]MCP-6827), [11C]HD-800 and [11C]colchicine have been developed for imaging microtubules (MTs) with positron emission tomography (PET).
Anton Lindberg   +13 more
doaj   +1 more source

Practical Radiosynthesis and Preclinical Neuroimaging of [11C]isradipine, a Calcium Channel Antagonist

open access: yesMolecules, 2015
In the interest of developing in vivo positron emission tomography (PET) probes for neuroimaging of calcium channels, we have prepared a carbon-11 isotopologue of a dihydropyridine Ca2+-channel antagonist, isradipine. Desmethyl isradipine (4-(benzo[c][1,
Benjamin H. Rotstein   +8 more
doaj   +1 more source

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