Results 11 to 20 of about 11,235 (223)

In vitro evaluation of photon and carbon ion radiotherapy in combination with cisplatin in head and neck squamous cell carcinoma cell lines

Frontiers in Oncology, 2023
BackgroundHeavy ion radiotherapy, such as carbon ion radiotherapy (CIRT), has multiple advantages over conventional photon therapy. Cisplatin, as a classic anti-tumor drugs, has been tested and discovered as a photon radiosensitizer in several cell lines,
Xumeng Fang, Xumeng Fang, Xumeng Fang, Pian Sun, Pian Sun, Pian Sun, Yuanli Dong, Yuanli Dong, Yuanli Dong, Yangle Huang, Yangle Huang, Yangle Huang, Jiade Jay Lu, Jiade Jay Lu, Jiade Jay Lu, Lin Kong, Lin Kong, Lin Kong   +17 more
doaj   +1 more source

Functional imaging-guided carbon ion irradiation with simultaneous integrated boost for localized prostate cancer: study protocol for a phase II randomized controlled clinical trial

Trials, 2022
Background Due to the physical dose distribution characteristic of “Bragg peak” and the biological effect as a kind of high linear energy transfer ray, heavy ion therapy has advantages over conventional photon therapy in both efficacy and safety.
Wei Hu, Ping Li, Zhengshan Hong, Xiaomao Guo, Yulei Pei, Zhenshan Zhang, Qing Zhang   +6 more
doaj   +1 more source

Carbon Ion Therapy: A Modern Review of an Emerging Technology

Frontiers in Oncology, 2020
Radiation therapy is one of the most widely used therapies for malignancies. The therapeutic use of heavy ions, such as carbon, has gained significant interest due to advantageous physical and radiobiologic properties compared to photon based therapy. By
Timothy D. Malouff, Anita Mahajan, Sunil Krishnan, Chris Beltran, Danushka S. Seneviratne, Daniel Michael Trifiletti   +5 more
doaj   +1 more source

Preliminary Safety and Efficacy of Proton Plus Carbon-Ion Radiotherapy With Concurrent Chemotherapy in Limited-Stage Small Cell Lung Cancer

Frontiers in Oncology, 2021
ObjectivesThis study aimed to investigate the tolerance and effect of proton plus carbon-ion radiotherapy with concurrent chemotherapy in limited-stage small cell lung cancer using the pencil beam scanning technique.Materials and MethodsFrom March 2017 ...
Ning-Yi Ma, Ning-Yi Ma, Ning-Yi Ma, Jian Chen, Jian Chen, Jian Chen, Xue Ming, Xue Ming, Xue Ming, Guo-Liang Jiang, Guo-Liang Jiang, Guo-Liang Jiang, Jiade J. Lu, Jiade J. Lu, Jiade J. Lu, Kai-Liang Wu, Kai-Liang Wu, Kai-Liang Wu, Jingfang Mao, Jingfang Mao, Jingfang Mao   +20 more
doaj   +1 more source

Carbon ion radiotherapy for sacral chordoma [PDF]

The British Journal of Radiology, 2011
The National Institute of Radiological Sciences in Chiba, Japan has offered carbon ion radiotherapy (CIRT) since 1994 using carbon ion beams generated by the heavy ion medical accelerator in Chiba (HIMAC). The total number of cases treated with the HIMAC exceeded 5000 in July 2009.
R, Imai, T, Kamada, S, Sugahara, H, Tsuji, H, Tsujii   +4 more
openaire   +2 more sources

Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion Radiotherapy. [PDF]

PLoS ONE, 2015
Monitoring mice exposed to carbon ion radiotherapy provides an indirect method to evaluate the potential for second cancer induction in normal tissues outside the radiotherapy target volume, since such estimates are not yet possible from historical ...
Benjamin J Blyth, Shizuko Kakinuma, Masaaki Sunaoshi, Yoshiko Amasaki, Shinobu Hirano-Sakairi, Kanae Ogawa, Ayana Shirakami, Yi Shang, Chizuru Tsuruoka, Mayumi Nishimura, Yoshiya Shimada   +10 more
doaj   +1 more source

Recent Innovations in Carbon-Ion Radiotherapy [PDF]

Journal of Radiation Research, 2010
In the last few years, hospital-based facilities for carbon-ion radiotherapy are being constructed and proposed in Europe and Asia. During the next few years, several new facilities will be opened for carbon-ion radiotherapy in the world. These facilities in operation or under construction are categorized in two types by the beam shaping method used ...
Shinichi, Minohara, Shigekazu, Fukuda, Nobuyuki, Kanematsu, Yuka, Takei, Takuji, Furukawa, Taku, Inaniwa, Naruhiro, Matsufuji, Shinichiro, Mori, Koji, Noda   +8 more
openaire   +2 more sources

Recurrent lumbar-origin osteoblastoma treated with multiple surgery and carbon ion radiotherapy: a case report

BMC Musculoskeletal Disorders, 2020
Background Although osteoblastoma is an uncommon benign bone tumor, it sometimes behaves in a locally aggressive fashion. We herein report a case of recurrent lumbar spine osteoblastoma that was treated by repeated surgery and carbon ion radiotherapy ...
Akira Honda, Yoichi Iizuka, Reiko Imai, Masahiro Nishinome, Junko Hirato, Hiromi Koshi, Tokue Mieda, Hiroyuki Sonoda, Sho Ishiwata, Yohei Kakuta, Tsuyoshi Tajika, Hirotaka Chikuda   +11 more
doaj   +1 more source

Carbon ion radiotherapy with complete tumor regression for primary malignant melanoma of female urethra orifice: a case report

Journal of International Medical Research, 2022
Primary malignant melanoma of the female urethra (PMMFU) is extremely rare, accounting for 0.2% of all melanomas, and fewer than 200 cases have been reported worldwide. Because of the small number of clinical cases and unclear biological characteristics,
Xiaojun Li, Yihe Zhang, Yanshan Zhang, Yancheng Ye, Ying Qi, Tingchao Hu, Xin Pan   +6 more
doaj   +1 more source

Treatment of Recurrent Undifferentiated Pleomorphic Sarcoma of Infratemporal Fossa by Surgery Combined With Carbon Ion Radiotherapy: One Case Report

Frontiers in Surgery, 2021
We retrospectively analyzed the diagnosis and treatment process of one patient with recurrent undifferentiated pleomorphic sarcoma (UPS) of infratemporal fossa and made a definite diagnosis by combining the imaging and pathological examination results ...
Zaixing Wang, Zhiyuan Tang, Hailiang Zhao, Xianhai Zeng, Xiaodong Han, Qiuhang Zhang   +5 more
doaj   +1 more source