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The impact of carbon and nitrogen catabolite repression in microorganisms
Microbiological Research, 2021Organisms have cellular machinery that is focused on optimum utilization of resources to maximize growth and survival depending on various environmental and developmental factors. Catabolite repression is a strategy utilized by various species of bacteria and fungi to accommodate changes in the environment such as the depletion of resources, or an ...
Saurabh Jyoti Sarma
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Carbon catabolite repression in bacteria
Current Opinion in Microbiology, 1999Carbon catabolite repression (CCR) is a regulatory mechanism by which the expression of genes required for the utilization of secondary sources of carbon is prevented by the presence of a preferred substrate. This enables bacteria to increase their fitness by optimizing growth rates in natural environments providing complex mixtures of nutrients.
Jörg Stülke, Wolfgang Hillen
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The mechanisms of carbon catabolite repression in bacteria
Current Opinion in Microbiology, 2008 Carbon catabolite repression (CCR) is the paradigm of cellular regulation. CCR happens when bacteria are exposed to two or more carbon sources and one of them is preferentially utilised (frequently glucose). CCR is often mediated by several mechanisms, which can either affect the synthesis of catabolic enzymes via global or specific regulators or ...
Deutscher, Josef
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Carbon catabolite repression in Aspergillus nidulans involves deubiquitination
Molecular Microbiology, 2001 The best studied role of ubiquitination is to mark proteins for destruction by the proteasome but, in addition, it has recently been shown to promote macromolecular assembly and function, and alter protein function, thus playing a regulatory role distinct from protein degradation.
Lockington, R., Kelly, J.
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Carbon catabolite repression in bacteria: many ways to make the most out of nutrients
Nature Reviews Microbiology, 2008 Most bacteria can selectively use substrates from a mixture of different carbon sources. The presence of preferred carbon sources prevents the expression, and often also the activity, of catabolic systems that enable the use of secondary substrates. This
Boris Gorke +2 more
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Soil Biology and Biochemistry, 2019 Microbial decomposition of Soil Organic Matter (SOM) is largely controlled by environmental and edaphic factors such as temperature, pH, and moisture. However, microbial metabolism is controlled by catabolite repression, which leads microbes to grow on ...
Daniele La Cécilia +2 more
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Null Alleles ofcreA,the Regulator of Carbon Catabolite Repression inAspergillus nidulans
Fungal Genetics and Biology, 1997 CreA is the major regulatory protein involved in carbon catabolite repression in Aspergillus nidulans. Previously we have reported the molecular characterization of a number of in vivo selected mutant alleles and showed that they were unlikely to ...
Michael J Hynes +2 more
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Carbon catabolite repression: not only for glucose
Current Genetics, 2019Most organisms prefer to utilize glucose as a carbon source. Accordingly, the expression of genes involved in the catabolism of other carbon sources is repressed by the presence of glucose in a process known as (carbon) catabolite repression. However, much less is known about the relationships between "poor" carbon sources.
Kobi Simpson-Lavy, Martin Kupiec
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The role of mitochondria in carbon catabolite repression in yeast
Molecular and General Genetics MGG, 1976The role of mitochondria in carbon catabolite repression in Saccharomyces cerevisiae was investigated by comparing normal, respiratory competent (RHO) strains with their mitochondrially inherited, respiratory deficient mutant derivatives (rho). Formation of maltase and invertase was used as an indicator system for the effect of carbon catabolite ...
P, Haussmann, F K, Zimmermann
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Mutants of Saccharomyces cerevisiae resistant to carbon catabolite repression
Molecular and General Genetics MGG, 1977Mutants with defective carbon catabolite repression have been isolated in the yeast Saccharomyces cerevisiae using a selective procedure. This was based on the fact that invertase is a glucose repressible cell wall enzyme which slowly hydrolyses raffinose to yield fructose and that the inhibitory effects of 2-deoxyglucose can be counteracted by ...
F K, Zimmermann, I, Scheel
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