Results 91 to 100 of about 28,620 (278)

INFLUENCE OF DOSE RATE ON THE CELLULAR RESPONSE TO LOW- AND HIGH-LET RADIATIONS

Frontiers in Oncology, 2016
Nowadays, head and neck squamous cell carcinoma (HNSCC) treatment failure is mostly explained by loco-regional progression or intrinsic radioresistance.
Anne-Sophie eWozny, Anne-Sophie eWozny, Gersende eAlphonse, Gersende eAlphonse, Priscillia eBattiston-Montagne, Stéphanie eSimonet, Delphine ePoncet, Delphine ePoncet, Etienne eTesta, Jean-Baptiste eGuy, Jean-Baptiste eGuy, Chloé eRancoule, Nicolas eMagne, Michael eBeuve, Claire eRodriguez-Lafrasse, Claire eRodriguez-Lafrasse   +15 more
doaj   +1 more source

Charged particle's flux measurement from PMMA irradiated by 80 MeV/u carbon ion beam

, 2012
Hadrontherapy is an emerging technique in cancer therapy that uses beams of charged particles. To meet the improved capability of hadrontherapy in matching the dose release with the cancer position, new dose monitoring techniques need to be developed and
A., Paoloni, Antonio Di, Domenico, Bellini, Fabio, C., Agodi, Cecilia, Voena, Collamati, Francesco, DI DOMENICO, Antonio, E., Vitale, Erika De, Lucia, F., Romano, Faccini, Riccardo, Ferroni, Fernando, Fiore, Salvatore, G. A. P., Cirrone, G., Battistoni, G., Cuttone, Gauzzi, Paolo, I., Mattei, Iarocci, Enzo, M., De Napoli, M., Marafini, Patera, Vincenzo, Piersanti, Luca, S., Muraro, Sarti, Alessio, Sciubba, Adalberto   +25 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Wireless Bioelectronic Modulation of Membrane Potential in Glioblastoma Using Carbon Nanotube Porins

Advanced Science, EarlyView.
A schematic illustrating glioblastoma cell membrane modulation using carbon nanotube porins (CNTPs) and an applied voltage. CNTPs enable ion flux leading to changes in membrane potential. This figure summarizes the concept of bioelectronic control of cell membrane voltage.
Fleur Groualle, David Onion, Julie A. Watts, Graham A. Rance, Aleksandr Noy, Beth Coyle, Frankie J. Rawson   +6 more
wiley   +1 more source

Randomised phase I/II study to evaluate carbon ion radiotherapy versus fractionated stereotactic radiotherapy in patients with recurrent or progressive gliomas: The CINDERELLA trial

BMC Cancer, 2010
Background Treatment of patients with recurrent glioma includes neurosurgical resection, chemotherapy, or radiation therapy. In most cases, a full course of radiotherapy has been applied after primary diagnosis, therefore application of re-irradiation ...
Haselmann Renate, Haberer Thomas, Jäkel Oliver, Habermehl Daniel, Rieken Stefan, Edler Lutz, Burkholder Iris, Combs Stephanie E, Unterberg Andreas, Wick Wolfgang, Debus Jürgen   +10 more
doaj   +1 more source

Overview of Carbon-ion Radiotherapy

Journal of Physics: Conference Series, 2017
The outcome of radiotherapy depends on potential efficiency of accelerators and their related accessories. In charged particle therapy before the 1990s, accelerators that were primarily installed for physics research had been shared, which however had limited flexibility for clinical use.
openaire   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, EarlyView.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source

Beyond Cocrystals: Hierarchical Functional Assemblies via Noncovalent Synthesis

Advanced Science, EarlyView.
Non‐covalent interactions (NCIs) drive the formation of organic cocrystals with diverse structures and tunable optoelectronic properties. This review explores the essential factors governing these properties, highlighting how the sequential nucleation of cocrystals leads to the self‐assembly of organic hierarchical structures (OHSs).
Ya‐Nan Zhu, Jin Feng, Ying‐Xin Ma, Hong‐Tao Lin, Li‐Wei Xie, Qi‐Liang Peng, Xue‐Dong Wang   +6 more
wiley   +1 more source

Study of the time and space distribution of beta+ emitters from 80 MeV/u carbon ion beam irradiation on PMMA

, 2012
Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments and the on-line knowledge of the Bragg peak position is still a matter of research.
A. Di Domenico, A. Paoloni, A. Sarti, A. Sciubba, Agodi, Agostinelli, Allison, Amaldi, C. Agodi, C. Voena, E. De Lucia, E. Iarocci, F. Bellini, F. Collamati, F. Ferroni, F. Romano, Fiedler, Fiedler, G. Cuttone, G.A.P. Cirrone, I. Mattei, Jan, L. Piersanti, M. De Napoli, M. Marafini, P. Gauzzi, Parodi, Pawelke, Priegnitz, Pshenichnov, R. Faccini, S. Fiore, Sommerer, V. Patera, Vecchio   +34 more
core   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

Advanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng, Ge Zhu, Siyu Sun, Wenbo Yao, Yuning Zhang, Yong‐Guang Yang, Tianmeng Sun   +6 more
wiley   +1 more source