Results 81 to 90 of about 11,143 (172)

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

BJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui, Marlene Elmelund, Niels Klarskov   +2 more
wiley   +1 more source

Fast microdosimetry algorithms in particle therapy: Benchmark and applicability guidelines

Precision Radiation Oncology, EarlyView.
Giorgio Cartechini, Marta Missiaggia, Francesco Giuseppe Cordoni   +2 more
wiley   +1 more source

Comparative 30‐day life cycle assessment of bladder drainage strategies

BJU International, EarlyView.
Objective To identify the most environmentally sustainable urinary drainage strategies commonly used to manage bladder outlet obstruction and also to highlight actionable levers for reducing the footprint of urinary drainage in clinical practice. Materials and Methods We conducted a comparative life cycle assessment of three urinary drainage strategies
Arthur Peyrottes, Thibaut Long‐Depaquit, Marc Fourmarier, Benjamin Pradere, Benoit Peyronnet, Laurent Zieleskiewicz, Alessandro Uleri, Jean‐Nicolas Cornu, Vincent Misrai, Richard Mallet, Michael Baboudjian, on behalf of the French Sustainability Task Force from the Association Française d'Urologie   +11 more
wiley   +1 more source

Advantages, limitations, and future perspectives of using TEPCs in clinical quality assurance

Precision Radiation Oncology, EarlyView.
Anna Bianchi, Anna Selva, Valeria Conte
wiley   +1 more source

Collagen Type VI Alpha 1 as a Regulator of Redox Homeostasis in Antioxidant‐Enhanced Osteogenesis of Dental Stem Cells

Cell Proliferation, EarlyView.
Under physiological conditions, NAC activates the PI3K‐AKT‐COL6A1 axis to sustain redox balance and enhance osteogenesis. COL6A1 deficiency, however, compromises this axis, inducing oxidative stress and impairing NAC's osteogenic efficacy. ABSTRACT Alveolar bone injury represents a prevalent clinical challenge in dentistry, for which stem cell‐based ...
Zhaosong Meng, Jiacheng Liu, Yue Zhang, Ruimeng Yang, Jingyi Zhang, Haosun Yang, Zheng Wang, Ran Wei, Zhe Li, Shuling Guo, Lizhi Hu, Lei Sui   +11 more
wiley   +1 more source

Experimental and computational characterisation of the secondary fragment field in clinical proton therapy beams using microdosimetry

Precision Radiation Oncology, EarlyView.
Gabriele Parisi, Marta Missiaggia, Enrico Pierobon, Francesco Cordoni, Enrico Verroi, Claudio Verona, Giuseppe Schettino, Chiara La Tessa   +7 more
wiley   +1 more source

A Zeolitic Pyrimidine Framework (ZPF) Nanoplatform Co‐Delivers a DNAzyme and a Protein Prodrug for Cascade‐Activated Tumour Therapy

Cell Proliferation, EarlyView.
A zeolitic framework co‐delivers a DNAzyme and a protein prodrug to tumour cells and executes a self‐amplifying therapeutic cascade: the DNAzyme elevates tumour oxidative stress to activate a caged RNase A prodrug. This spatiotemporally controlled synergy converts a genetic input into potent enzymatic cytotoxicity, suppressing tumour growth.
Yan Huang, Xingjie Hu, Jinli Sun, Min Yin, Nan Chen   +4 more
wiley   +1 more source

From Cold to Hot: Nanozyme‐Based Strategies for Reprogramming the Tumour Immunoenvironment

Cell Proliferation, EarlyView.
Nanozymes, with multi‐enzyme catalytic activities, reprogram the immunosuppressive tumour microenvironment by inducing immunogenic cell death, relieving hypoxia, and depleting antioxidants, effectively converting immunologically “cold” tumours into “hot” ones to boost cancer immunotherapy efficacy.
Yue Wang, Miao Xu, Yongshun Wang, Xuan Lin, Qiang Zhang, Xiaoning Lin, Xin Wu, Cheng Zhang, Wenhua Huang, Jianlin Shen   +9 more
wiley   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Estimating the Sodium Content: A Case Series of Benign and Malignant Renal Tumours Using 23Na‐MRI at 3 T

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
23Na‐MRI at 3 T was applied to estimate TSC in patients with kidney tumours of different pathologies, which are indistinguishable on conventional imaging methods. The apparent TSC was significantly higher in renal oncocytomas (benign) compared to chromophobe renal cell carcinomas (malignant): 162 ± 58 mM vs. 71 ± 2 mM (p < 0.05).
Ines Horvat‐Menih, Jonathan R. Birchall, Maria J. Zamora‐Morales, Alice Bebb, Joshua D. Kaggie, Frank Riemer, Andrew B. Gill, Andrew N. Priest, Marta Wylot, Iosif A. Mendichovszky, Anne Y. Warren, James Jones, James N. Armitage, Thomas J. Mitchell, Grant D. Stewart, Mary A. McLean, Ferdia A. Gallagher   +16 more
wiley   +1 more source