Results 171 to 180 of about 28,984 (253)

Inhibitory Activity of Conferone on FAK Activity and Glutamine Metabolism in Human Colorectal Cancer

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Colorectal cancer (CRC) is a major global cause of death, with metastases and chemotherapy resistance contributing to poor outcomes. To identify natural compounds with anticancer potential against CRC and elucidate their action mechanisms, the cytotoxicity of 37 natural compounds was evaluated against the HCT116, leading to the identification ...
Hien Thi My Ong, Eda Ates, Jaeyong Jung, Jeong Soo Sung, Jae‐Chul Pyun, Min‐Jung Kang   +5 more
wiley   +1 more source

Application of intrahepatic fiducial markers in carbon ion radiotherapy for pancreatic cancer-Achieving higher precision treatment. [PDF]

J Appl Clin Med Phys
Nagata J, Kusano Y, Komori M, Takayama Y, Kurokawa S, Ito A, Kamada T, Yoshida D, Kawashiro S, Katoh H.   +9 more
europepmc   +1 more source

In Vitro Evaluation of PARP1 Inhibitor Olaparib‐Cyanine Dye Conjugate for the Treatment of Glioblastoma

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Inhibition of DNA damage repair is a common mechanism to induce cancer cell death and, therefore, to treat cancers such as breast, prostate and ovarian cancer. This approach, although very attractive, has not been feasible for treating brain tumours due to the stringent structural features necessary for pharmaceutical agents to cross the blood–brain ...
Carina Dumo, Faheem, Peter J. Choi, Nicholas J. Pederson, Yuge Liu, Mike Dragunow, Thomas I‐H. Park, Katharine L. Diehl, Jiney Jose   +8 more
wiley   +1 more source

Exploratory case series of conversion to carbon ion radiotherapy after systemic therapy in advanced hepatocellular carcinoma. [PDF]

Int Cancer Conf J
Anzai H, Miwa C, Ogasawara S, Fujiya M, Kurosaki H, Tsuchiya T, Yoshino R, Katayama K, Sawada M, Akatsuka T, Izai R, Yonemoto T, Yumita S, Koroki K, Inoue M, Nakamura M, Kanogawa N, Nakamoto S, Makishima H, Shinoto M, Wakatsuki M, Yamada S, Ishikawa H, Kato J.   +23 more
europepmc   +1 more source

Computational and Spectroscopic Insights Into the Rice Bran Derived Glu‐Gln‐Arg‐Pro‐Arg Pentapeptide as an Anticancer Agent: A DFT, Molecular Docking, and Molecular Dynamics Study

International Journal of Quantum Chemistry, Volume 126, Issue 8, April 15, 2026.
Rice bran–derived neutral EQRPR (L‐Glu‐L‐Gln‐L‐Arg‐L‐Pro‐L‐Arg) pentapeptide was structurally and biologically characterized using DFT calculations, vibrational spectroscopy, molecular docking, and molecular dynamics simulations. The DFT/wb97xd/6–31++G(d,p) level of theory showed the best agreement with the experimental spectra.
Gozde Yilmaz, Sefa Celik, Aysen E. Ozel, Sevim Akyuz   +3 more
wiley   +1 more source

MVI-targeted carbon-ion radiotherapy combined with immunotherapy for advanced hepatocellular carcinoma: Phase Ib DEPARTURE trial. [PDF]

JHEP Rep
Ogasawara S, Koroki K, Makishima H, Wakatsuki M, Takahashi A, Fujiya M, Yumita S, Nakagawa M, Kanzaki H, Kobayashi K, Inoue M, Nakamura M, Kanogawa N, Kondo T, Nakamoto S, Kurokawa T, Ozawa Y, Inaba Y, Paritala S, Chen J, Lee J, Hoshida Y, Hanaoka H, Yamada S, Ishikawa H.   +24 more
europepmc   +1 more source

SP-038: Carbon ion radiotherapy

Radiotherapy and Oncology, 2019
openaire   +1 more source

Carbon Ion Radiotherapy for Liver Cancer

Carbon Ion Radiotherapy for Liver Cancer
The objective of this paper is to present a summary of a clinical study on carbon ion radiotherapy (C-ion RT) for hepatocellular carcinoma (HCC) conducted from April 1995 to August 2005 at the Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, in Japan.
openaire   +1 more source

AI-based prediction of recurrence after carbon ion radiotherapy for early stage non-small cell lung cancer. [PDF]

PLoS One
Miyasaka Y, Yoshida H, Okano N, Shimada H, Kubo N, Kawamura H, Ohno T.   +6 more
europepmc   +1 more source

Evaluation of Magnetic Resonance Imaging-Derived Synthetic Computed Tomography in Prostate Cancer Carbon Ion Radiotherapy: Impact of Fixation Shell. [PDF]

Int J Part Ther
Ishizawa M, Haga K, Sato H, Miyasaka Y, Souda H, Chai H, Iwai T.   +6 more
europepmc   +1 more source