Results 91 to 100 of about 2,289,697 (227)

In Situ Bioorthogonal Synthesis of PROTACs via Dual‐Responsive Cleavage for Synergistic Photo‐Immunotherapy

Advanced Science, EarlyView.
A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian, Jiasha Wu, Fusheng Xu, Yan Zuo, Huaxing Shen, Rui Ji, Luyi Wang, Na Li, Yanting Sun, Yongsheng Yu, Yejiao Shi, Honggang Hu, Feng Xu, Dan Huang, Xiaochun Hu   +14 more
wiley   +1 more source

Stable Isotope Compositions of Wild and Farmed S. Paramoamosion and its Implication for Tracebility

Journal of Isotopes, 2014
To evaluate the possibility of using stable isotopes for discriminating wild and farmed mangrove crabs, Stable carbon and nitrogen isotope ratios of Scylla paramamosion tissues were analyzed. The carbon and nitrogen isotope ratios of wild S. paramamosion
GUO Jie-min1,2;LIN Guang-hui1,3
doaj   +1 more source

Osmium Nanoparticle Anchoring on CoFe Layered Double Hydroxides Enables High‐Valent Species Stabilization and Efficient Seawater Oxygen Evolution

Advanced Science, EarlyView.
Osmium nanoparticles anchored on CoFe layered double hydroxide (Os/CoFe LDH) stabilize high‐valent Co/Fe species and modulate the interfacial water configuration via surface engineering. This work presents a facile surface engineering strategy for constructing efficient and durable OER electrocatalysts for alkaline seawater, and expands the ...
Xindong She, Guosheng Zhou, Kanghua Miao, Junjie Gong, Mingzhe Jiang, Xueting Zhu, Zhenzhen Wang, Shijie Shen, Wenwu Zhong   +8 more
wiley   +1 more source

Variation in the carbon and nitrogen isotopic signatures of pig remains from prehistoric sites in the Near East and Central Europe [PDF]

, 2013
The first results of carbon and nitrogen (δ13C, δ15N) stable isotope analyses of domestic pig (Sus domesticus Erxl., 1777) remains from three prehistoric sites are presented.
Bartosiewicz, Laszlo, Pickard, Catriona, Bonsall, Clive, Schoop, Ulf-Dietrich, Vaughan, Maureen   +4 more
core  

Cryo‐EM and NMR Reveal a Membrane‐Gated Doc2B–Munc13‐1 Complex and a Helical Doc2B‐SNARE‐Binding Interface

Advanced Science, EarlyView.
Biophysical studies of Doc2B yield a cryo‐electron microscopy structure of its complex with the synaptic vesicle priming factor Munc13‐1 and its binding site to the SNARE complex that mediates synaptic vesicle fusion. These and other results suggest a novel model whereby Doc2 proteins regulate neurotransmitter release through sequential interactions ...
Cyrus T. Rastegar, Julia Powell, Aleksandra Wosztyl, Guillaume David, Klaudia Jaczynska, Xiao‐chen Bai, Yan Han, Zhe Chen, Josep Rizo   +8 more
wiley   +1 more source

Strong coupling of shoot assimilation and soil respiration during drought and recovery periods in beech as indicated by natural abundance δ13C measurements

Frontiers in Plant Science, 2016
Drought down-regulates above- and belowground carbon fluxes, however, the resilience of trees to drought will also depend on the speed and magnitude of recovery of these above- and belowground fluxes after re-wetting. Carbon isotope composition of above-
Carola Heide Blessing, Carola Heide Blessing, Matti Barthel, Lydia Gentsch, Nina Buchmann   +4 more
doaj   +1 more source

Rhizodeposition Drives One Third of Belowground Carbon Input in Agroecosystems

Advanced Science, EarlyView.
This study quantifies photosynthesized C allocation in the plant–soil system across six crop types: barley, wheat, maize, rice, legumes and grasses. It reports C partitioning into shoot respiration, shoot‐C, root‐C, net rhizodeposition and root‐derived CO2, providing standardized percentage averages and GPP‐derived absolute values as a robust baseline ...
Zhengjun Yan, Yuan Wen, Jie Zhou, Yakov Kuzyakov, Damien Beillouin, Johannes Lehmann, Yadong Yang, Yiqi Luo, Pete Smith, Zhaohai Zeng, Huadong Zang   +10 more
wiley   +1 more source

Carbon Isotopic Chemistry [PDF]

Symposium - International Astronomical Union, 1992
Isotopic molecular abundances are used to interpret Galactic chemical evolution and the properties of interstellar clouds. The isotopic chemistry of carbon plays an important role in the interpretation of these measurements. This paper reviews the recent measurements of the carbon twelve to thirteen ratio across the Galaxy and the isotopic chemistry.
openaire   +1 more source

Soil pH Amelioration Synergizes Carbon Accrual with Yield Gains Under Organic Substitution

Advanced Science, EarlyView.
Soil pH shifts towards neutrality in both acidic and alkaline soils under organic substitution. A global synthesis links pH amelioration to soil organic carbon accrual through enhanced microbial biomass after accounting for added organic carbon and its interaction with pH. This pH amelioration‐shared soil organic carbon accrual accounts for 5.1–8.6% of
Xunzhuo Dong, Yanzhong Yao, Bingbing Han, Yunyao Zhong, Benyi Li, Mengfei Li, Yunchao Dai, Zhaolei Li   +7 more
wiley   +1 more source

Carbon Isotope Chemistry in Protoplanetary Disks: Effects of C/O Ratios

The Astrophysical Journal
Carbon isotope fractionation of CO has been reported in the disk around TW Hya, where elemental carbon is more abundant than elemental oxygen ([C/O] _elem > 1).
Seokho Lee, Hideko Nomura, Kenji Furuya
doaj   +1 more source