Results 41 to 50 of about 21,848 (142)

Androgen deprivation, androgen receptor-targeted vaccination, and nivolumab in patients with high-risk localized prostate cancer

Journal for ImmunoTherapy of Cancer
Background In murine studies, we demonstrated that a DNA vaccine encoding the androgen receptor (pTVG-AR) given prior to androgen deprivation elicited prostate tumor-infiltrating lymphocytes and an antitumor response.
Wei Huang, Douglas G McNeel, Jens Eickhoff, David Jarrard, Laura Johnson, Donghwan Jeon, Christos E Kyriakopoulos, Tommaso P Tonelli   +7 more
doaj   +1 more source

PD-1 blockade employed at the time CD8+ T cells are activated enhances their antitumor efficacy

Journal for ImmunoTherapy of Cancer
Background We have previously shown that immune checkpoint receptors, including PD-1, are upregulated on T cells at the time of their activation, and that blockade of these receptors can improve the efficacy of antitumor vaccines.
Douglas G McNeel, Donghwan Jeon, Ichwaku Rastogi, Jena E Moseman   +3 more
doaj   +1 more source

Efficacité du dioxyde de carbone comme attractif pour Glossina tachinoides en savane humide d'Afrique de l'Ouest

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1986
Dans la perspective de l'étude des attractifs olfactifs des glossines du groupe palpalis, il est important de connaître le rôle joué par le dioxyde de carbone.
J.B. Galey, P. Mérot, André Mitteault, J. Filledier, H. Politzar   +4 more
doaj   +1 more source

Determination of carbon-carbon connectivities, assignment of quaternary carbons, and extraction of carbon-carbon coupling constants by carbon-relayed hydrogen-carbon spectroscopy

Journal of Magnetic Resonance (1969), 1985
Nowadays many possibilities exist to elucidate carbon-carbon connectivity. In hydrogen-bearing carbon systems C-C connectivities can be traced out most conveniently in an indirect way by a combination of H-H COSY (I) and H-C CQSY (2). In case of overlapping ‘proton signals ambiguities can be removed by heteronuclear relayed spectroscopy (3) and ...
Kessler, Horst, Bermel, W., Griesinger, Christian   +2 more
openaire   +2 more sources

Cellulose carbon-CVD carbon composites

Carbon, 1975
Carbon-carbon composites have been fabricated using a cellulose powder which is molded at low pressures, carbonized at 800°C and infiltrated by a CVD technique at 700°C using propylene as a source of carbon. Infiltration rate at time t is governed by the amount of open porosity existing in the sample at this time.
S. Marinkovic, P.W. Whang, A. Navarrete, P.L. Walker   +3 more
openaire   +2 more sources

Trajectoire de la forêt des Landes (1850-2022) : un puits de carbone soumis à des dynamiques sociales et écologiques changeantes

Revue Forestière Française
Depuis la mise en place du massif forestier landais au milieu du XIXe siècle, de profondes mutations du métabolisme socio-écologique territorial se sont succédé : l’abandon du système agro-pastoral traditionnel, l’exploitation d’une forêt conçue pour le
Thérèse Rabotin, Dalia Fages-Gouyou, Gilles Billen, Julia Le Noë   +3 more
doaj   +1 more source

Toll like receptor agonist effects on human CD8+ T cell activation and expression of T cell checkpoint receptors

Human Vaccines & Immunotherapeutics
We have previously found that murine CD8+ T cells activated with cognate antigen increase the expression of PD-1 and other checkpoint receptors, and this can be attenuated in the presence of specific Toll-like receptor (TLR) agonists.
Donghwan Jeon, Jena E. Moseman, Ethan Hill, Douglas G. McNeel   +3 more
doaj   +1 more source

Analyse intégrée de la flore, de la diversité des adventices et du stockage du carbone du sol de trois agrosystèmes maraîchers tropicaux du sud Togo

Revue Congolaise des Sciences et Technologies
Face à l’intensification des pratiques agricoles et aux pressions anthropiques croissantes sur les ressources naturelles, les agrosystèmes tropicaux sont confrontés à une double exigence : maintenir leur productivité tout en préservant les fonctions ...
Agbamaro Massama-Esso , Madjouma Kanda, Abalo Atato, Essossimna Magamana, Wouyo Atakpama, Banlipo Djakambi, Baholy Rahelivololoniaina Robijaona, Marra Dourma, Komlan Batawila, Koffi Akpagana   +9 more
doaj   +1 more source

Variabilité du carbone dans les différentes fractions organiques du sol suivant les modes d’utilisation des terres en Afrique de l’Ouest

Revue Marocaine des Sciences Agronomiques et Vétérinaires, 2022
La nature de la matière organique dans les différentes fractions granulométriques est un meilleur indicateur du niveau de dégradation du sol. La présente étude a pour objectif d’évaluer les influences des différents modes d’utilisation des terres sur la ...
Christophe Codjo ATCHADA, Tobi Moriaque AKPLO   +1 more
doaj  

Dynamic reciprocal interactions between activated T cells and tumor associated macrophages drive macrophage reprogramming and proinflammatory T cell migration within prostate tumor models

Scientific Reports
Tumor-associated macrophages (TAMs) have been implicated as a tumor microenvironment (TME) cell population, which may be playing a vital role in the inhibition of effective T cell responses in the prostate TME.
Erika Heninger, Matthew Thomas Breneman, Emma Elizabeth Recchia, Sheena Catherine Kerr, Reyna Elvan Dogru, Marina Nasrin Sharifi, Aaron Matthew LeBeau, David Kosoff   +7 more
doaj   +1 more source