Results 161 to 170 of about 130,822 (183)

Intracellular Binding/Unbinding Kinetics of Approved Drugs to Carbonic Anhydrase II Observed by in-Cell NMR. [PDF]

open access: yesACS Chem Biol, 2020
Luchinat E   +5 more
europepmc   +1 more source

Carbonic anhydrase II does not regulate nitrite-dependent nitric oxide formation and vasodilation. [PDF]

open access: yesBr J Pharmacol, 2020
Wang L   +10 more
europepmc   +1 more source

Carbonic anhydrase gene expression in CA II‐deficient (Car2−/−) and CA IX‐deficient (Car9−/−) mice

open access: green, 2006
Peiwen Pan   +6 more
openalex   +1 more source

Fluorinated pyrrolidines and piperidines incorporating tertiary benzenesulfonamide moieties are selective carbonic anhydrase II inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2015
A series of substituted pyrrolidines and piperidines were synthesized using superacid HF/SbF5 chemistry. Investigated as inhibitors of several human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms, i.e.
Alexandre Le Darz   +7 more
semanticscholar   +1 more source

Refined structure of human carbonic anhydrase II at 2.0 Å resolution

Proteins: Structure, Function, and Bioinformatics, 1988
The structure of human erythrocytic carbonic anhydrase II has been refined by constrained and restrained structure–factor least‐squares refinement at 2.0 Å resolution. The conventional crystallographic R value is 17.3%.
A. Eriksson, T. Jones, A. Liljas
semanticscholar   +1 more source

Carbonic anhydrase II is found in the placenta of a viviparous, matrotrophic lizard and likely facilitates embryo-maternal CO2 transport.

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 2015
The evolution of viviparity requires the development of mechanisms that facilitate transport of respiratory gases between mother and developing embryo. Of particular importance is maternal excretion of embryonic carbon dioxide (CO2 ), which increases as ...
J. V. Van Dyke   +3 more
semanticscholar   +1 more source

Carbonic anhydrase II deficiency in 12 families with the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification.

New England Journal of Medicine, 1985
Osteopetrosis with renal tubular acidosis and cerebral calcification was identified as a recessively inherited syndrome in 1972. In 1983, we reported a deficiency of carbonic anhydrase II, one of the isozymes of carbonic anhydrase, in three sisters with ...
W. Sly   +11 more
semanticscholar   +1 more source

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