Carbonic anhydrase II enhances activity of monocarboxylate transporters via direct interaction
Becker Holger +4 more
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Abstract Immediate responses to hypoxia at high altitude are hyperventilation and successive respiratory alkalosis. Alkalosis, in turn, can affect cerebrospinal fluid pH and ventilatory control. The kidneys compensate metabolically for respiratory alkalosis.
Elisabeth Skalla +9 more
wiley +1 more source
Computational insights into novel inhibitors: virtual screening of small molecules against human carbonic anhydrase II. [PDF]
Arunachalam S, M M B, Gnanasekaran R.
europepmc +1 more source
Comment on the article Structure and mechanism of copper-carbonic anhydrase II: a nitrite reductase. [PDF]
Tsikas D.
europepmc +1 more source
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
wiley +1 more source
Conformational flexibility of His200 enables catalytic activity in the T200H mutant of carbonic anhydrase II. [PDF]
Lim SW +5 more
europepmc +1 more source
Design, Synthesis, Kinetic Analysis and Pharmacophore-Directed Discovery of 3-Ethylaniline Hybrid Imino-Thiazolidinone as Potential Inhibitor of Carbonic Anhydrase II: An Emerging Biological Target for Treatment of Cancer. [PDF]
Ahmed A +10 more
europepmc +1 more source
Synthesis, molecular modeling, and biological evaluation of 4‐[5‐aryl‐3‐(thiophen‐2‐yl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and
Cem Yamalı +4 more
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