Results 71 to 80 of about 69,223 (345)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Shiyou shiyan dizhiMulti-phase transpressive strike-slip faults are well developed in the Carboniferous strata of the Chepaizi Uplift, Junggar Basin. These faults are characterized by severe weathering at the top, strong heterogeneity, poor stratification, and indistinct ...
Shiqi GUI +7 more
doaj +1 more source
The Western Irish Namurian Basin reassessed [PDF]
, 2000 Current basin models for the Western Irish Namurian Basin (WINB) envisage an elongate trough along the line of the present-day Shannon Estuary that was infilled with clastic sediments derived from a hinterland that lay to the W or NW.
Best, J.L., Wignall, P.B.
core
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
The Diatomeæ of the carboniferous period [PDF]
Annals and Magazine of Natural History, 1875 (1875). The Diatomeae of the carboniferous period. Annals and Magazine of Natural History: Vol. 15, No. 86, pp. 164-164.
openaire +2 more sources
FEBS Open Bio, EarlyView.Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi +5 more
wiley +1 more source
Carboniferous Forest at Oldham [PDF]
Nature, 1880 IT may perhaps be interesting to the readers of NATURE to know that here at Oldham we have recently laid bare a fine sample of a carboniferous forest. We are here, as you are aware, situated on the middle coal-measures, Oldham Edge (800 feet) being the highest outcrop of that series.
openaire +2 more sources
A reconnaissance geochemical drainage survey of the Criffel-Dalbeattie granodiorite complex and its environs [PDF]
, 1977 Regional geochemical reconnaissance by stream sediments and panned concentrates was undertaken over an area of 850 km 2 of south-west Scotland. Rocks of Ordovician to Permian age are exposed within the area but the major part is occupied by the ...
Brown, M.J. +3 more
core
Discriminating faunal assemblages and their palaeoecology based on museum collections : the Carboniferous Hurlet and Index limestones of western Scotland [PDF]
, 2010 Historical collections of Scottish Carboniferous macrofossils stored at the British Geological Survey (BGS), Edinburgh include the sole remaining sources of palaeontological data from numerous localities.
Akhurst, M.C. +3 more
core +2 more sources
FEBS Open Bio, EarlyView.Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
wiley +1 more source