Results 71 to 80 of about 68,132 (365)
Baseline Scotland : groundwater chemistry of the Carboniferous sedimentary aquifers of the Midland Valley [PDF]
This report describes the baseline groundwater chemistry of the sedimentary aquifers of Carboniferous age in the Midland Valley of Scotland. Groundwater is an important resource in the Midland Valley, largely for agriculture, but also for industry ...
Darling, W.G.+4 more
core
Sedimentology and kinematics of a large, retrogressive growth-fault system in Upper Carboniferous deltaic sediments, western Ireland [PDF]
Growth faulting is a common feature of many deltaic environments and is vital in determining local sediment dispersal and accumulation, and hence in controlling the resultant sedimentary facies distribution and architecture.
Busch D.A.+12 more
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
IV.—On the Carboniferous Polyzoa [PDF]
As so much remains to be done before the Palæozoic Polyzoa can be properly classified—more particularly the Carboniferous species—it seems to me that the wisest course to adopt is to go carefully over the work of other authors, reviewing their labours generally, and giving, in as condensed a form as possible, the results of their varied efforts.
openaire +2 more sources
Shifts in hexapod diversification and what Haldane could have said [PDF]
Data on species richness and taxon age are assembled for the extant hexapod orders (insects and their six-legged relatives). Coupled with estimates of phylogenetic relatedness, and simple statistical null models, these data are used to locate where, on ...
Davies D. A. L.+2 more
core +3 more sources
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella+18 more
wiley +1 more source
A platysomid occurrence from the Tournaisian of Nova Scotia
The Hangenberg extinction has been hypothesized as a first order event in vertebrate evolution; however, information on the earliest Carboniferous vertebrate fauna, crucial in evaluating biodiversity changes, is scarce.
Conrad D. Wilson+2 more
doaj +1 more source
Gold in Carboniferous Conglomerate [PDF]
MANY of your readers are aware that the fact of the occurrence of gold in Lower Carboniferous conglomerate as in New South Wales is not at all new. The Gay's River Gold Field of Nova Scotia, where the gold occurs in Lower Carboniferous conglomerate resting on the edges of Cambrian slates having small veins of auriferous quartz, was first pointed out by
openaire +2 more sources
Evolution of leaf-form in land plants linked to atmospheric CO2 decline in the Late Palaeozoic era [PDF]
The widespread appearance of megaphyll leaves, with their branched veins and planate form, did not occur until the close of the Devonian period at about 360 Myr ago.
AH Knoll+32 more
core +1 more source
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang+9 more
wiley +1 more source