Results 101 to 110 of about 30,254 (254)

Biodegradation of Pyrethroids by a Hydrolyzing Carboxylesterase EstA from Bacillus cereus BCC01

open access: yesApplied Sciences, 2019
Microbial degradation has been considered as a rapid, green, and cost-effective technique to reduce insecticide pollutions in a contaminated environment.
Wei Hu, Qiqi Lu, G. Zhong, M. Hu, Xin Yi
semanticscholar   +1 more source

Permeability of 16 Straight‐ and Branched‐Chain Parabens Using the Caco‐2 Assay

open access: yesJournal of Applied Toxicology, Volume 46, Issue 2, Page 652-668, February 2026.
ABSTRACT The in vitro intestinal permeability of straight‐ and branched‐chain parabens has not been extensively investigated. Sixteen parabens were tested in the Caco‐2 assay. Passive diffusion was measured using PAMPA. The transport of the MCT1 substrate, p‐coumaric acid, as well as propylparaben and isopropylparaben, was investigated.
Nicola J. Hewitt   +3 more
wiley   +1 more source

cDNA cloning and characterization of the carboxylesterase pxCCE016b from the diamondback moth, Plutella xylostella L.

open access: yesJournal of Integrative Agriculture, 2016
Carboxylesterase is a multifunctional superfamily and can be found in almost all living organisms. As the metabolic enzymes, carboxylesterases are involved in insecticides resistance in insects for long time.
Zhen-di HU   +7 more
doaj   +1 more source

In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 2, February 2026.
Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Xiao‐Jian Zhou   +9 more
wiley   +1 more source

Detection of carboxylesterase by a novel hydrosoluble near-infrared fluorescence probe

open access: yesRSC Advances, 2019
A novel hydrosoluble near-infrared fluorescence off–on probe has been developed for detecting carboxylesterase activity. The probe was designed by introducing (4-acetoxybenzyl)oxy as a quenching and recognizing moiety to the decomposed product of IR-783,
Mengyao Li   +5 more
semanticscholar   +1 more source

Heterologous expression and characterization of a malathion-hydrolyzing carboxylesterase from a thermophilic bacterium, Alicyclobacillus tengchongensis [PDF]

open access: yes, 2013
A carboxylesterase gene from thermophilic bacterium, Alicyclobacillus tengchongensis, was cloned and expressed in Escherichia coli BL21 (DE3). The gene coded for a 513 amino acid protein with a calculated molecular mass of 57.82 kDa.
Bo Xu   +6 more
core   +1 more source

The Role of Soil Microorganisms in Microplastic Biodegradation: Mechanisms, Carbon Preferences, and Ecological Impacts

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This work explores the complex relationship between soil carbon availability and microplastic biodegradation, highlighting competition and symbiosis among microorganisms, the repurposing of microplastic‐derived polymers, and the impact of soil organic carbon on microbial substrate preferences and carbon use efficiency variability.
Mohammad Yaghoubi Khanghahi   +3 more
wiley   +1 more source

Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor

open access: yesChemical Science, 2019
We report the development of a ratiometric fluorescent chemosensor that selectively measures human carboxylesterase 2 (hCES2) activity with application in pancreatic cancer patient-derived xenografts.
Karishma Kailass   +6 more
semanticscholar   +1 more source

Intrinsic Factors Influencing Simvastatin and Simvastatin Acid Pharmacokinetics: Age‐Related Studies in Thai Adults and Cross‐Population Comparisons

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Intrinsic factors such as age and ethnicity influence statin pharmacokinetics (PK) and may increase the risk of muscle‐related adverse events. This study investigated the effect of age on the PK of simvastatin (SV) and its active metabolite, simvastatin acid (SVA), in healthy Thai subjects using an LC–MS/MS assay while accounting for key ...
Thanate Srimatimanon   +11 more
wiley   +1 more source

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