Results 101 to 110 of about 27,172,362 (207)

Seven fatalities associated with ethylphenidate [PDF]

, 2016
Ethylphenidate is a stimulant novel psychoactive substance that is an analogue of the prescription drug methylphenidate (Ritalin®). Methylphenidate is used commonly for the treatment of attention deficit hyperactivity disorder.
Bailey, Faraj, Glennon, Ho, Koehm, Krueger, L. Hikin, Lin, Markowitz, Markowitz, Marsh, Martinez-Raga, Matuszewski, Meyer, Nakajima, P.D. Maskell, P.R. Smith, Parks, Patrick, Patrick, Peters, Pignon, Portoghese, Pounder, Quinney, R. Cole, Rothman, S.R. Morley, Shimizu, Soussan, Spensley, Srinivas, Stark, Thomsen, Wargin, Williard, Zhu, Zhu   +37 more
core   +1 more source

Human plasma carboxylesterase 1, a novel serologic biomarker candidate for hepatocellular carcinoma

PROTEOMICS, 2009
AbstractTo identify and characterize a serologic glycoprotein biomarker for hepatocellular carcinoma (HCC), multi‐lectin affinity chromatography was used to isolate intracellular N‐linked glycoprotein fractions from five paired non‐tumor and tumor tissues.
Keun, Na, Eun-Young, Lee, Hyoung-Joo, Lee, Kwang-Youl, Kim, Hanna, Lee, Seul-Ki, Jeong, An-Sung, Jeong, Sang Yun, Cho, Sun A, Kim, Si Young, Song, Kyung Sik, Kim, Sung Won, Cho, Hoguen, Kim, Young-Ki, Paik   +13 more
openaire   +3 more sources

Immunogenic Modulations Induced by Prospective Anti-Malarial Herbal Extracts in Murine Model [PDF]

, 2010
Keeping in view the ever increasing problem of drug resistance and affordability of the antimalarial drugs by the poor mass, herbal medicines can become an important and alternative sustainable strategy for malaria treatment.
Chinmoy Karjee, Dipankar Singha, Guruprasad Mandal, Manoj Das, Niladri Sekhar Bhunia, Sajal Ray, Sanat Biswas, Shyamal Das Gupta, Sreemayee Sarkar, Sudipta Chakraborty, Suman Mukherjee, Swapna Chhetri   +11 more
core   +1 more source

IL-33 Downregulates Hepatic Carboxylesterase 1 in Acute Liver Injury via Macrophage-derived Exosomal miR-27b-3p. [PDF]

J Clin Transl Hepatol, 2023
Gao P, Li M, Lu J, Xiang D, Wang X, Xu Y, Zu Y, Guan X, Li G, Zhang C.   +9 more
europepmc   +1 more source

The COVID-19 Medicine Remdesivir Is Therapeutically Activated by Carboxylesterase-1, and Excessive Hydrolysis Increases Cytotoxicity. [PDF]

Hepatol Commun, 2021
Shen Y, Eades W, Yan B.
europepmc   +1 more source

Relationship among expression, amplification, and methylation of FE4 esterase genes in Italian populations of Myzus persicae (Sulzer) (Homoptera : Aphididae) [PDF]

, 2005
The wide use of insecticides containing an esteric group selected resistant Myzus persicae populations characterised by the overproduction of one of two closely related carboxylesterases (E4 and FE4). In this paper, we present data collected from Italian
CASSANELLI, Stefano, D. Bizzaro, E. Barbolini, E. Mazzoni, F. Pavesi, MANICARDI, Gian Carlo, P. Cravedi, S. Giannini   +7 more
core  

Identification of regulatory variants of carboxylesterase 1 (CES1): A proof-of-concept study for the application of the Allele-Specific Protein Expression (ASPE) assay in identifying cis-acting regulatory genetic polymorphisms. [PDF]

Proteomics, 2023
Her L, Shi J, Wang X, He B, Smith LS, Jiang H, Zhu HJ.   +6 more
europepmc   +1 more source

Physiologically-Based Pharmacokinetic Modeling to Predict Methylphenidate Exposure Affected by Interplay Among Carboxylesterase 1 Pharmacogenetics, Drug-Drug Interactions, and Sex. [PDF]

J Pharm Sci, 2022
Xiao J, Shi J, Thompson BR, Smith DE, Zhang T, Zhu HJ.   +5 more
europepmc   +1 more source

Plasma Carboxylesterase 1 Predicts Methylphenidate Exposure: A Proof-of-Concept Study Using Plasma Protein Biomarker for Hepatic Drug Metabolism. [PDF]

Clin Pharmacol Ther, 2022
Shi J, Xiao J, Wang X, Jung SM, Bleske BE, Markowitz JS, Patrick KS, Zhu HJ.   +7 more
europepmc   +1 more source

Contributions of Cathepsin A and Carboxylesterase 1 to the Hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis. [PDF]

Drug Metab Dispos, 2022
Li J, Shi J, Xiao J, Tran L, Wang X, Zhu HJ.   +5 more
europepmc   +1 more source