Results 61 to 70 of about 5,456,471 (384)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Direct deoxygenative borylation of carboxylic acids

Nature Communications, 2021
Converting a carboxylic acid into a boronic acid, which makes a useful chemical handle from a feedstock chemical, currently relies on decarboxylation and requires metal catalysts and prior functionalization.
Jianbin Li, Chia-Yu Huang, Mohamad Ataya, Rustam Z. Khaliullin, Chao-Jun Li   +4 more
doaj   +1 more source

Monolayer protection for eletrochemical migration control in silver nanocomposite [PDF]

, 2006
©2006 American Institute of Physics. The electronic version of this article is the complete one and can be found online at: http://link.aip.org/link/?APPLAB/89/112112/1DOI:10.1063/1.2353813The authors introduced an effective approach of using monolayer ...
Li, Yi, Wong, C. P.
core   +1 more source

Hydrocarbon Synthesis via Photoenzymatic Decarboxylation of Carboxylic Acids

Journal of the American Chemical Society, 2019
A recently discovered photodecarboxylase from Chlorella variabilis NC64A (CvFAP) bears the promise for the efficient and selective synthesis of hydrocarbons from carboxylic acids.
Wuyuan Zhang, M. Ma, Mieke M. E. Huijbers, G. Filonenko, E. Pidko, Morten M. C. H. van Schie, Sabrina Rose de Boer, B. Burek, Jonathan Z. Bloh, W. V. van Berkel, Wilson A. Smith, F. Hollmann   +11 more
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Impact of Dispersing on the Production and Extraction of Bio-Based Basic Chemicals from Biogenic Secondary Waste

Environmental and Climate Technologies
Biogenic waste from waste treatment plants, secondary waste, can be used to produce bio-based carboxylic acids, conventionally produced by chemical synthesis from petroleum-based feedstocks or by synthesis from natural oils.
Vogt Kyra Atessa, Steinberg Iris
doaj   +1 more source

Influence of chain length and saturation on carboxylic acid pyrolysis mechanisms

Fuel Processing Technology
This study investigates radical-driven deoxygenation mechanisms during the non-catalytic pyrolysis of saturated and unsaturated carboxylic acids. Pyrolysis experiments were conducted at 410 °C, between 0.5 and 2 h, using carboxylic acids of varying ...
Bernardo A. Souto, Justice Asomaning, David C. Bressler   +2 more
doaj   +1 more source

Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades.

Journal of the American Chemical Society, 2019
The alkylation of amines with either alcohols or carboxylic acids represents a mild and safe alternative to the use of genotoxic alkyl halides and sulfonate esters.
J. I. Ramsden, Rachel S. Heath, Sasha R. Derrington, S. L. Montgomery, J. Mangas-Sánchez, K. Mulholland, N. Turner   +6 more
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Chemoselective Hydrodeoxygenation of Carboxylic Acids to Hydrocarbons over Nitrogen-Doped Carbon–Alumina Hybrid Supported Iron Catalysts

ACS Catalysis, 2019
The establishment of catalyst systems for the chemoselective hydrodeoxygenation (HDO) of carboxylic acids to hydrocarbons, such as the HDO of long-chain fatty acids to alkanes, is important for bio...
Jiang-Bing Li, Jun-jie Zhang, Shuai Wang, Guangyue Xu, Hao Wang, D. Vlachos   +5 more
semanticscholar   +1 more source