Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019) [PDF]
, 2019 The broad interdisciplinary nature of biocatalysis fosters innovation, as different technical fields are interconnected and synergized. A way to depict that innovation is by conducting a survey on patent activities.
Alcántara, Andrés R. +2 more
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The structure of a novel thermophilic esterase from the planctomycetes species, thermogutta terrifontis reveals an open active site due to a minimal 'cap' domain. [PDF]
, 2015 Published under the CC-BY license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and the source are credited.A carboxyl esterase (TtEst2) has been identified in a novel thermophilic bacterium,
Ingham, C +4 more
core +1 more source
The synthesis and characterization of polypeptide-adriamycin conjugates and its complexes with adriamycin. Part I [PDF]
, 1985 Poly(α-l-glutamic acid) (PGA) was grafted with amino acid and oligopeptide spacers up to 5 amino acids with the use of N,N'-carbonyldiimidazole and 2,3-dihydro-1,2-benz-isothiazole-3-on-1, 1-dioxide (saccharin) as an additive, and these polypeptides were
Eenink, M.J.D. +5 more
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Microbial Cell Factories, 2008 Background Lipolysis is an important process of cheese ripening that contributes to the formation of flavour. Propionibacterium freudenreichii is the main agent of lipolysis in Emmental cheese; however, the enzymes involved produced by this species have ...
Canaan Stéphane +3 more
doaj +1 more source
Improving the 'tool box' for robust industrial enzymes. [PDF]
, 2017 This is the final version of the article. Available from Springer Verlag via the DOI in this record.The speed of sequencing of microbial genomes and metagenomes is providing an ever increasing resource for the identification of new robust biocatalysts ...
Littlechild, JA
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Conformational behaviour of mannuronic acid based azasugars [PDF]
, 2017 A set of mannuronic acid based iminosugars, comprising the C-5-carboxylic acid, -methyl ester and -amide analogues of 1-deoxymannorjirimicin (DMJ), was synthesized and their pH dependent conformational behavior studied. Under acidic conditions the methyl
Akhlaghinia +42 more
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Lipase catalysed kinetic resolution of racemic 1,2-diols containing a chiral quaternary center [PDF]
, 2018 Optically active 1,2-diols are valuable buildings blocks in organic synthesis. In the present paper, a set of racemic 1,2-diols with an ester functional group are prepared, starting from -ketoesters in a three-step procedure with moderate yields.
Gonzalo Calvo, Gonzalo de
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Esterase mutation is a mechanism of resistance to antimalarial compounds [PDF]
, 2017 Pepstatin is a potent peptidyl inhibitor of various malarial aspartic proteases, and also has parasiticidal activity. Activity of pepstatin against cultured Plasmodium falciparum is highly variable depending on the commercial source.
Corey, Victoria C +6 more
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Why Leave a Job Half Done? Recent Progress in Enzymatic Deracemizations [PDF]
, 2015 Financial support of this work by the Spanish MICINN (Projects CTQ2011-24237 and CTQ2013-44153) is gratefully ...
Díaz Rodríguez, Alba +2 more
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Disordered N-termini enhance the thermostability of SGNH-hydrolase family polyesterases. [PDF]
Protein SciAbstract Polyesters are widely used plastics that persist in the environment due to their resistance to degradation. Microbial polyesterases potentially offer recycling and remediation solutions. However, most polyesterases lack the thermostability and catalytic efficiency required for practical application.
Ahmed FH +7 more
europepmc +2 more sources