Results 91 to 100 of about 1,999 (189)

Identification of Carboxymethyllysine Forming Sites by Nonenzymatic Glycation of Human Serum Albumin in Vitro

, 2016
Human serum albumin（HSA）is an abundant plasma protein and is modified by glucose in plasma. The incubation of HSA with glucose at 37℃ for four weeks resulted in the formation of carboxymethyllysine in 11 sites of lysine residues of HSA（65, 190 . .
松本, 孝, シゲナガ, アヤコ, イトウ, ミカ, YAMAKURA, Fumiyuki, ITOH, Mika, 重永, 綾子, SHIGENAGA, Ayako, ヤマクラ, フミユキ, マツモト, タカシ, 山倉, 文幸, 伊藤, 美香, MATSUMOTO, Takashi   +11 more
core  

An industrially applicable processing method for reducing AGEs in bread based on RSM design

Future Foods
Intake of dietary advanced glycation end-products (AGEs) is associated with increased risk of inflammation and chronic disease. Bread, a significant source of AGEs, is an ideal model for minimizing AGEs at process scale.
Guanhua Jiang, Haili Yu, Liangkai Chen, Yan Zhang, Liegang Liu   +4 more
doaj   +1 more source

Serum carboxymethyl-lysine, a dominant advanced glycation end product, is increased in women with gestational diabetes mellitus

Biomedical Papers, 2016
Aims: The objective of the study was to measure one of the circulating Advanced Glycation End Products (AGEs) - Nε-(carboxymethyl)lysine (CML) - in a case-control study (n = 307) of pregnant women with gestational diabetes mellitus (GDM) and ...
Vendula Bartakova, Radana Kollarova, Katarina Kuricova, Katarina Sebekova, Jana Belobradkova, Katerina Kankova   +5 more
doaj   +1 more source

Formation of free and protein-bound carboxymethyllysine and carboxyethyllysine in meats during commercial sterilization

, 2016
The effect of commercial sterilization treatments on the levels of advanced glycation endproducts (AGEs) in meats was investigated. The amounts of both free and protein-bound N(ε)-carboxymethyllysine (CML) and N(ε)-carboxyethyllysine (CEL) in beef (rump,
Juming Tang, Xiaohua Sun, Yiqun Huang, Wang, Jing, Tang, Juming, Barbara A. Rasco, Rasco, Barbara A, Lai, Keqiang, Jing Wang, Keqiang Lai, Huang, Yiqun, Sun, Xiaohua   +11 more
core   +1 more source

Concentrations of N6-Carboxymethyllysine (CML), N6-Carboxyethyllysine (CEL), and Soluble Receptor for Advanced Glycation End-Products (sRAGE) Are Increased in Psoriatic Patients

, 2022
Psoriasis is a chronic, recurrent, and often severe skin disease which is frequently associated with metabolic disorders and increased risk of cardiovascular complications.
Agnieszka Nowak, Nowak, Agnieszka, Aleksandra Damasiewicz-Bodzek, Damasiewicz-Bodzek, Aleksandra   +3 more
core   +1 more source

The advanced glycation endproduct Nε-carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention [PDF]

, 2018
Diabetes is an established risk factor for pancreatic cancer (PaC), together with obesity, Western diet and tobacco smoking. The common mechanistic link might be the accumulation of advanced glycation endproducts (AGEs), which characterizes all the above
Stefano Menini, Iacobini, Carla, Pugliese, Giuseppe, Paola Cappello, Piaggio, Giulia, Carla Iacobini, Cappello, Paola, Isabella Manni, Luisa de Latouliere, Giuseppe Pugliese, Ionta, Vittoria, Manni, Isabella, Francesco Novelli, Menini, Stefano, Claudia Blasetti Fantauzzi, de Latouliere, Luisa, Pesce, Carlo, Giulia Piaggio, Carlo Pesce, Blasetti Fantauzzi, Claudia, Novelli, Francesco, Vittoria Ionta   +21 more
core   +1 more source

Exposure of Caenorhabditis elegans to Dietary Nε-Carboxymethyllysine Emphasizes Endocytosis as a New Route for Intestinal Absorption of Advanced Glycation End Products

, 2021
International audienceThe impact of dietary advanced glycation end products (dAGEs) on human health has been discussed in many studies but, to date, no consensual pathophysiological process has been demonstrated.
Taront, Solenne, Frédéric J. Tessier, Litke, Rachel, Paul-Constant, Charles, Stéphane Rianha, Tessier, Frédéric, Fradin, Chantal, Jean-Marc Lo Guidice, Dubois, Constance, Lo Guidice, Jean-Marc, Charles Paul-Constant, Eric Boulanger, Rachel Litke, Boulanger, Eric, Chantal Fradin, Solenne Taront, Constance Dubois, Rianha, Stéphane   +17 more
core   +1 more source

Nε-carboxymethyllysine in nutritional milk formulas for infants

, 2018
Production of infant formulas involves high temperature processing for microbiological safety. However, heat processes generate Advanced Glycation End-products (AGEs), including Nε-carboxymethyllysine (CML) formed between lysine and lactose.
Alison Hodgkinson (15394178), Elizabeth Carpenter (15397100), Colin Prosser (15395060)   +2 more
core  

Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain

, 2013
Mitochondrial maintenance crucially depends on the quality control of proteins by various chaperones, proteases and repair enzymes. While most of the involved components have been studied in some detail, little is known on the biological role of the ...
Fischer, Fabian, Hamann, Andrea, Weil, Andrea, Osiewacz, Heinz D.   +3 more
core   +1 more source

Early and advanced stages of Maillard reaction in infant formulas: Analysis of available lysine and carboxymethyl-lysine.

PLoS ONE, 2019
Although the literature on the Maillard reaction in infant formulas is extensive, most studies have focused on model systems, and in only a few cases on real food systems.
Kataneh Aalaei, Ingegerd Sjöholm, Marilyn Rayner, Cristina Teixeira, Eden Tareke   +4 more
doaj   +1 more source