The use of quantum dots to amplify antigen detection [PDF]
Proposal to develop an Improved immunological assay employing primary IgG antibodies and secondary IgM antibodies labeled with quantum dots to amplify antigen detection.
arxiv
Carcinoembryonic Antigen Serum Levels in Nonmelanoma Skin Cancer
Background: Carcinoembryonic antigen (CEA) is a glycoprotein, which is present in the foetal colon, some benign conditions and different malignancies, particularly in colon adenocarcinoma. We focused this study on non-melanoma skin cancer (NMSC). NMSC is
Saverio Latteri+9 more
doaj +1 more source
Markers of inflammation and bone remodelling associated with improvement in clinical response measures in psoriatic arthritis patients treated with golimumab [PDF]
<p>Objective To determine serum biomarker associations with clinical response to golimumab treatment in patients with psoriatic arthritis (PsA).</p> <p>Methods GO–REVEAL was a randomised, placebo-controlled study of golimumab in ...
Beutler, A.+12 more
core +1 more source
Label‐Free Microscale Technologies for Isolation of Heterogeneous Circulating Tumor Cells
The isolation of circulating tumor cells (CTCs) from liquid biopsy samples is crucial for cancer treatment and monitoring. This review evaluates primary label‐free isolation methods for capturing heterogeneous CTCs and examines their potential to provide deeper insights into tumor heterogeneity and dynamics of cancer progression.
Gürhan Özkayar+5 more
wiley +1 more source
Canalization of the evolutionary trajectory of the human influenza virus [PDF]
Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. Antigenic evolution occurs in the context of a two-dimensional 'antigenic map', while genetic evolution shows a characteristic ladder-like genealogical tree. Here, we use a large-scale individual-based model to show that evolution in a Euclidean
arxiv
Primitive Neuroectodermal Tumor Presenting with Elevating Carcinoembryonic Antigen
Primitive neuroectodermal tumor (PNET) is a rare disease and mostly diagnosed in children and young adults. This tumor is presumed to be of neuroectodermal origin, probably developing from migrating embryonic cells of the neural crest.
Hsiao-Hsiang Cheng, Chuang-Chi Liaw
doaj +1 more source
Biochemical markers in cancer of the ovary : a review [PDF]
The ideal tumour marker would be one which is detectable before obvious clinical involvement. A number of biochemical markers have been used to diagnose carcinoma of the ovary.
Cauchi, Maurice N.
core
Targeted therapy of advanced gallbladder cancer and cholangiocarcinoma with aggressive biology: eliciting early response signals from phase 1 trials. [PDF]
PurposePatients with advanced cholangiocarcinoma (CC) and gallbladder carcinoma (GC) have few therapeutic options for relapsed disease. methods: Given the overall poor prognosis in this population and the availability of novel targeted therapies, we ...
Falchook, Gerald S+14 more
core +2 more sources
On‐paper enzyme‐linked and metal‐linked immunosorbent assays (p‐ELISA and p‐MeLISA, respectively) were developed for the assay of carcinoembryonic antigen (CEA) in serum. These approaches are based on bio‐conjugated paper disks as analytical platform.
Electra Mermiga+4 more
wiley +1 more source
SPECIFIC CARCINOEMBRYONIC ANTIGENS OF THE HUMAN DIGESTIVE SYSTEM [PDF]
Phil Gold, Samuel O. Freedman
openalex +1 more source