Results 111 to 120 of about 451,263 (262)

Development of a Nomogram‐Based Clinical Estimation Model for Pathological Upstaging in Patients With Preoperative Ductal Carcinoma In Situ

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Preoperative diagnosis of ductal carcinoma in situ (DCIS) may be followed by pathological upstaging to invasive ductal carcinoma (IDC) upon surgical excision, a discrepancy that significantly impacts surgical planning and decisions regarding sentinel lymph node biopsy (SLNB).
Yu‐Hua Chen, Chung‐Liang Li, Ping‐Fu Yang, Hui‐Hua Hsiao, Fang‐Ming Chen, Sin‐Hua Moi   +5 more
wiley   +1 more source

CA199 and CEA expression levels, and minimally invasive postoperative prognosis analysis in esophageal squamous carcinoma patients

Open Medicine
This study explores the factors related to the expression levels of carbohydrate antigen 199 (CA199) and carcinoembryonic antigen (CEA) and their association with poor postoperative prognosis in patients with esophageal squamous cell carcinoma (ESCC) who
Ji Cheng, Ji Lingjia, Wang Fei, Zhang Anping, Shen Liang   +4 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Protecting CEACAM1 Expression Prevents Diet‐Induced Metabolic Dysfunction and Hepatic Fibrosis in Male Mice

Obesity, EarlyView.
ABSTRACT Objective High‐fat diet represses Ceacam1 transcription via a PPARα‐mediated mechanism to cause insulin resistance before inflammation develops. The current study investigated whether mutating PPRE‐RXRα in Ceacam1 promoter prevents diet‐induced metabolic abnormalities and hepatic fibrosis in male C57BL6/J mice.
Raziyeh Abdolahipour, Saja S. Khuder, William M. Philbrick, Agnes O. Portuphy, Getachew D. Belew, Hatem G. Fallouh, Harrison T. Muturi, Boyeon Kim, Jason K. Kim, Sonia M. Najjar   +9 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

VIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao, Qiyu Huang, Juan Xiao, Ziyu Liu, Xinyan Zou, Yuying Liu, Lizhi Liu, Musheng Zeng, Chuanbo Xie   +8 more
wiley   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

VIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi, Ngoan Thi Thao Nguyen, Riccardo Zulli, Jacopo Giaretta, Fariba Dehghani, Syamak Farajikhah   +5 more
wiley   +1 more source

Improving tumor marker comparability: A case series on harmonizing carbohydrate antigen 19‐9 and carbohydrate antigen 15‐3 measurements across diverse measurement systems

VIEW, EarlyView.
CA19‐9 and CA15‐3 measurements from seven contemporary immunoassay systems were compared using 464 and 499 native serum samples, respectively. Inter‐system correlations were higher for CA15‐3 than for CA19‐9, and only a limited number of systems met biological variation‐derived bias criteria.
Jia Li, Xiaoying Lou, Zongdan Wang, Mengdi Wu, Jing Zhang, Huishuang Gao, Meng Li, Bing Wu, Dongmei Ma, Kuo Zhang, Wei Cui   +10 more
wiley   +1 more source

Expression of a glycoprotein of the carcinoembryonic antigen family in normal and neoplastic sebaceous glands - Limited role of carcinoembryonic antigen as a sweat gland marker

, 1996
Background: Carcinoembryonic antigen (CEA) is a well-known marker for sweat gland differentiation in adnexal ...
Neumaier, Michael, Hartig, Christine, Luger, Thomas A., Grunert, Fritz, Metze, Dieter, Soyer, H.-Peter, Wagener, Christoph, Grunert, F, Bhardwaj, R, Bhardwaj, Ranjit, Metze, D, Neumaier, M, Amann, Udo, Zelger, B, Hartig, C, Amann, U, Wagener, C, Zelger, Bernhard, Luger, TA, Soyer, HP   +19 more
core   +1 more source

Per Protocol Analysis and Long‐Term Outcomes of Laparoscopic Radical Resection for Gallbladder Cancer Compared With Open Method

World Journal of Surgery, EarlyView.
Although laparoscopic radical resection for gallbladder (GB) cancer has been attempted, only a limited number of studies have evaluated its outcomes using a per‐protocol analytical approach. ABSTRACT Background Although laparoscopic radical resection for gallbladder (GB) cancer has been attempted, only a limited number of studies have evaluated its ...
Tae Ho Hong, Kwang Yeol Paik, Yoon kyung Woo, Jae Hyun Han, Jung Woo Lee, Jong Woo Lee, Dong Do You   +6 more
wiley   +1 more source