Results 111 to 120 of about 84,117 (291)

Combined Detection of Preoperative Serum Calcitonin and Carcinoembryonic Antigen in Medullary Thyroid Carcinoma: A Retrospective Multicenter Cohort Study

Health Care Science, EarlyView.
Compared with the detection of either marker alone, the combined detection of calcitonin (Ctn) and carcinoembryonic antigen (CEA) improved the diagnostic accuracy for medullary thyroid cancer (MTC) but did not enhance the positive predictive value (PPV).
Yu Yang, Yufei He, Bo Lin, Yuanyuan Zheng, Xinyi Deng, Wenxin Chen, Zhenbang Ke, Yue Qiu, Yuting Hong, Jiayuan Zhang, Guojie Dong, Siqi Qiao, Ziyi Xin, Xuyang Li, Tianyi Xu, Wenke Chen, Xinwen Chen, Yingtong Hou, Fenghua Lai, Jianyan Long, Zhanqiang Zhang, Xiangdong Xu, Yihao Liu   +22 more
wiley   +1 more source

Personalized Precision in Healthcare Payment Systems: Insights From a Real‐World Cancer Patients Cohort Study

Health Care Science, EarlyView.
We developed an effective prediction model for reasonably high hospitalization costs, using gastric cancer surgery patients as an example. Integrating this assessment into the healthcare payment system based on diagnosis‐related groups is expected to improve the individualization and precision of health insurance fund utilization.
Kan Xue, Hongrui Tian, Qi Wang, Yinkui Wang, Fei Shan, Yansui Yang, Miao Yu, Zhonghu He, Ziyu Li, Jiafu Ji   +9 more
wiley   +1 more source

Association Between Multi‐Laboratory Parameters Pre‐ and Post‐Treatment and Pathological Features and Their Values in Clinical Decision in Primary Hepatic Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
Primary hepatic cancer (PHC), especially hepatocellular carcinoma (HCC), is still a significant burden worldwide. The efficacy of diagnosis, treatment response monitoring, and prognostication using laboratory biomarkers is still a challenge. This study analyzed multi‐laboratory parameters pre‐ and post‐treatment and their associations with clinical and
Xiaowei Chi, Weifang Liu, Zihan Liu, Jie Liu   +3 more
wiley   +1 more source

Optimizing Lymph Node Staging in Gallbladder Cancer: A Cutoff of 11 Nodes for Accurate Staging and Improved Survival

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Gallbladder cancer (GBC) is an aggressive malignancy in which lymph node (LN) status is a key prognostic factor. Adequate LN retrieval is essential for accurate nodal staging. This study aimed to identify an LN threshold that reduces false node‐negative (false N0) rates and to evaluate its association with overall survival (OS) as ...
So Jeong Yoon, Hyun Jeong Jeon, Boram Park, Hyeong Seok Kim, Hochang Chae, Sang Hyun Shin, In Woong Han, Jin Seok Heo, Okjoo Lee, Hongbeom Kim   +9 more
wiley   +1 more source

Mice Transgenic for the Human Carcinoembryonic Antigen Gene Maintain Its Spatiotemporal Expression Pattern [PDF]

, 1994
The tumor marker carcinoembryonic antigen (CEA) is predominantly expressed in epithelial cells along the gastrointestinal tract and in a variety of adenocarcinomas.
Eades-Perner, Anne-Marie, Hirth, Antje, Kleist, Sabine von, Neumaier, Michael, Putten, Herman van der, Thompson, John A., Zimmermann, Wolfgang   +6 more
core  

Deciphering nodal burden in thyroid carcinoma: A dedicated survey of age, lymph node ratio, log odds of positive nodes, and preoperative prediction models

Journal of Intelligent Medicine, EarlyView.
Abstract Evidence regarding the prognosis of thyroid carcinoma is heterogeneous, ranging from age effects and nodal burden metrics, such as lymph node ratio (LNR) and log odds of positive nodes (LODDS), to preoperative imaging models comprising ultrasound, CEUS, and radiomics.
Mennatallah Sherif, Mohanad A. Deif, Eman K. Elsayed   +2 more
wiley   +1 more source

Proteomics‐Based Identification of the Pyroptosis‐Related Biomarker PCSK9 and Its Association With the Pathogenesis of Rheumatoid Arthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang, Hao‐Jie Chen, Ting‐Ting Wu, Xin‐Yi Shen, Ying‐Ying Gao, Yu‐Feng Yin, Tian Ren, Xin Chu, Jing Cao, Tao Cheng, Ming‐Jun Wang   +10 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Molecular Diagnostics in Thyroid Nodules: Current Applications, Clinical Value, and Future Perspective

Med Research, EarlyView.
ABSTRACT Molecular diagnostics have become an important adjunct to ultrasonography and fine‐needle aspiration (FNA) for thyroid nodules, especially in Bethesda III/IV cytology where malignancy risk is uncertain. This narrative review summarizes the diagnostic and prognostic value of key genomic drivers (BRAF V600E, RAS, RET, TERT, and selected fusions)
Guohui Xiao, Min Ding, Zhixue Min, Yihan Dong, Xuanye Cao, Qiang Lu, Cong Chen, Yahui Wu, Xin Guo, Zhen Wu, Jing Xie, Dan Xu, Haizhen Chen, Rongli Xie, Jian Fei   +14 more
wiley   +1 more source

Tumor Markers in Patients with Chronic Renal Failure

The International Journal of Biological Markers, 1990
In order to evaluate the specificity of tumor markers in chronic renal failure, we have determined serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19.9 (CA 19.9), carbohydrate antigen 50 (CA 50), alfafetoprotein (AFP), neuron ...
X. Filella, A. Cases, R. Molina, J. Jo, J.L. Bedini, L. Revert, A.M. Ballesta   +6 more
doaj   +1 more source