Preoperative Serum Levels of Sialyl Lewisa, Sialyl Lewisx, and Carcinoembryonic Antigens as Prognostic Factors after Resection for Primary Breast Cancer [PDF]
Sialyl Lewisa (CA19-9) and sialyl LewisX antigens (CSLEXI) may play a role in tumor metastasis by serving as functional ligands in the cell adhesion system. To determine their prognostic value, we examined preoperative serum levels of CA19-9, CSLEXI, and
Itoyanagi, Noriaki +7 more
core
Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang +6 more
wiley +1 more source
Lymph node metastasis risk factors in T2 colorectal cancer
Objectives This study evaluates risk factors for lymph node metastasis (LNM) in T2 colorectal cancer to refine patient selection for endoscopic resection. Methods We reviewed records from consecutive patients who had undergone curative surgical resection
Yuriko Morita +21 more
doaj +1 more source
Combined Detection of Preoperative Serum Calcitonin and Carcinoembryonic Antigen in Medullary Thyroid Carcinoma: A Retrospective Multicenter Cohort Study. [PDF]
Compared with the detection of either marker alone, the combined detection of calcitonin (Ctn) and carcinoembryonic antigen (CEA) improved the diagnostic accuracy for medullary thyroid cancer (MTC) but did not enhance the positive predictive value (PPV).
Yang Y +22 more
europepmc +2 more sources
Distribution of carcinoembryonic antigen and biologic behavior in colorectal carcinoma.
PURPOSE: Carcinoembryonic antigen is assumed from the results of several experiments to be associated with invasion of colorectal carcinoma by adhesion or contact inhibition.
Wan S. Kim +17 more
core +1 more source
CEACAM6 gene variants in inflammatory bowel disease. [PDF]
The carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) acts as a receptor for adherent-invasive E. coli (AIEC) and its ileal expression is increased in patients with Crohn's disease (CD). Given its contribution to the pathogenesis of CD,
Seiderer, J. +67 more
core +1 more source
Medullary thyroid carcinoma (MTC) is a rare malignancy accounting for approximately 5% of all thyroid cancers. Common predictors of aggressiveness of MTC include specific RET mutations and levels of calcitonin.
Andrew Glaza, Jeffrey Margolis
doaj +1 more source
Preoperative CYFRA 21-1 and CEA as Prognostic Factors in Patients with Stage I Non-Small Cell Lung Cancer [PDF]
Objective: To validate the prognostic value of preoperative levels of CYFRA 21-1, CEA and the corresponding tumor marker index (TMI) in patients with stage I non-small cell lung cancer (NSCLC). Methods: Two hundred forty stage I NSCLC patients (80 in pT1
Hatz, Rudolf +7 more
core +1 more source
Objectives: Dihydrodiol dehydrogenase 2 (DDH2) plays an important role in pathogenesis of non-small-cell lung cancer (NSCLC). This study aimed to evaluate the value of serum DDH2 levels in NSCLC patients.
Chun-Hua Xu +6 more
doaj +1 more source
Expression of a neuroendocrine gene signature in gastric tumor cells from CEA 424-SV40 large T antigen-transgenic mice depends on SV40 large T antigen. [PDF]
A large fraction of murine tumors induced by transgenic expression of SV40 large T antigen (SV40 TAg) exhibits a neuroendocrine phenotype. It is unclear whether SV40 TAg induces the neuroendocrine phenotype by preferential transformation of progenitor ...
Georg Enders (187983) +32 more
core +1 more source

