Results 101 to 110 of about 84,117 (291)

Convergent evolution of pregnancy-specific glycoproteins in human and horse [PDF]

, 2016
Pregnancy-specific glycoproteins (PSGs) are members of the carcinoembryonic antigen cell adhesion molecule (CEACAM) family that are secreted by trophoblast cells. PSGs may modulate immune, angiogenic and platelet responses during pregnancy.
Amanda M de Mestre, Baker, Denis Aleksic, Donaldson, Fialova, Jana Hänske, Johannes Handler, Jordan E Read, Lisa Blaschke, Robert Kammerer, Ronan O’Riordan, Schumacher, Sophie Mißbach, Tom Moore, Victoria Cabrera-Sharp, Wiebke Weiß, Wolfgang Zimmermann   +16 more
core   +2 more sources

Management Strategies for Disappearing Colorectal Liver Metastases After Systemic Chemotherapy: Long‐Term Outcomes and Preoperative Prediction of ‘True Complete Response’

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Determining whether to resect disappearing liver metastases (DLMs) after chemotherapy for colorectal liver metastases (CRLMs) remains challenging. Methods Patients who underwent hepatectomy after systemic chemotherapy for initially unresectable CRLMs were reviewed. True complete response (CR) was defined as either resected DLMs with
Taihei Soma, Ryo Ashida, Takeshi Kawakami, Katsuhisa Ohgi, Mihoko Yamada, Shimpei Otsuka, Yoshiyasu Kato, Kentaro Yamazaki, Katsuhiko Uesaka, Teiichi Sugiura   +9 more
wiley   +1 more source

Preoperative Computed Tomography Colonography‐Angiography for Vascular Mapping to Guide and Standardize D3 Lymphadenectomy in Right‐Sided and Transverse Colon Cancer

Annals of Gastroenterological Surgery, EarlyView.
This study utilized high‐resolution CT colonography‐angiography to systematically classify vascular branching patterns in 591 patients. We defined four reproducible anatomical patterns each for right hemicolectomy and transverse colectomy, demonstrating that an independent‐origin middle colic artery consistently predicts shorter dissection distances ...
Takeharu Kato, Yukihide Kanemitsu, Mototaka Miyake, Gen Tomizawa, Kohei Takura, Hiroshi Nagata, Yasuyuki Takamizawa, Konosuke Moritani, Shunsuke Tsukamoto   +8 more
wiley   +1 more source

Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]

, 2009
We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Altschuler Y., Gabius H.J., Gendler S., Gouyer V., Hennebicq-Reig S., Huang J., Ligtenberg M.J., Ninomiya H., Yamashita K.   +8 more
core   +3 more sources

Lymph node metastasis risk factors in T2 colorectal cancer

DEN Open
Objectives This study evaluates risk factors for lymph node metastasis (LNM) in T2 colorectal cancer to refine patient selection for endoscopic resection. Methods We reviewed records from consecutive patients who had undergone curative surgical resection
Yuriko Morita, Shin‐ei Kudo, Yuki Takashina, Katsuro Ichimasa, Yuta Kouyama, Shigenori Semba, Kenichi Mochizuki, Osamu Shiina, Shun Kato, Takanori Kuroki, Shoji Shimada, Kenta Nakahara, Yusuke Takehara, Shunpei Mukai, Noriyuki Ogata, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Naruhiko Sawada, Tetsuo Nemoto, Toshiyuki Baba, Masashi Misawa   +21 more
doaj   +1 more source

Impact of extended insurance coverage on survival outcomes among patients with metastatic colorectal cancer in Taiwan

British Journal of Clinical Pharmacology, EarlyView.
Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang, Chen‐Han Chueh, Chien‐Yu Tseng, Christopher N. Kaufmann, Earl J. Morris, Chiao‐En Wu, Yi‐Wen Tsai   +6 more
wiley   +1 more source

Medullary Thyroid Cancer Discovered Through Elevated Carcinoembryonic Antigen Levels Post Colorectal Cancer Resection

Annals of Internal Medicine: Clinical Cases
Medullary thyroid carcinoma (MTC) is a rare malignancy accounting for approximately 5% of all thyroid cancers. Common predictors of aggressiveness of MTC include specific RET mutations and levels of calcitonin.
Andrew Glaza, Jeffrey Margolis
doaj   +1 more source

Diagnostic value of serum dihydrodiol dehydrogenase 2 levels in patients with non-small-cell lung cancer

The International Journal of Biological Markers, 2018
Objectives: Dihydrodiol dehydrogenase 2 (DDH2) plays an important role in pathogenesis of non-small-cell lung cancer (NSCLC). This study aimed to evaluate the value of serum DDH2 levels in NSCLC patients.
Chun-Hua Xu, Ding-Yu Ren, Yu-Chao Wang, Qian Zhang, Xiu-Wei Zhang, Li-Hua Qian, Jie-Bao Shao   +6 more
doaj   +1 more source

Potential interactions between traditional Chinese medicine and osimertinib: a Case Report

Frontiers in Pharmacology
Osimertinib, a third-generation EGFR tyrosine kinase inhibitor, played a crucial role in the treatment of EGFR-mutated non-small cell lung cancer. This case firstly reported a case of drug-drug interaction between traditional Chinese medicine (TCM) and ...
Min Zhang, Huiwen Ma, Wanyi Chen, Zhongzhen Yuan   +3 more
doaj   +1 more source

A Novel Magnetoelastic Immunosensor for Ultrasensitively Detecting Carcinoembryonic Antigen

Nanoscale Research Letters, 2018
A novel wireless immunosensor is developed for the ultra-sensitive detection of carcinoembryonic antigen. The optimum dimension of the microchips, as magnetoelastic sensitive units, was evaluated by simulation and experiments.
Yixia Zhang, Xing Guo, Lu Fan, Qiang Zhang, Shengbo Sang   +4 more
doaj   +1 more source