Results 121 to 130 of about 65,176 (294)

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Approaching Gold‐Standard Sensitivity in a Portable and Versatile Gold Nanoprisms Thermoplasmonic Platform for Lateral Flow Detection of Biomolecules

open access: yesSmall, EarlyView.
This study presents a plasmonic thermal lateral flow (ThermoLFA) biosensor for ultrasensitive, early detection of biomolecules. By combining plasmonic gold nanoprisms (AuNPrs) and near‐infrared (NIR) laser activation, it enhances signal output beyond conventional LFAs.
Carlos Cuestas Ayllón   +5 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

open access: yesVIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Clinical value of carcinoembryonic antigen for predicting the incidence of brain metastases and survival in small cell lung cancer patients treated with prophylactic cranial irradiation

open access: yes, 2018
Dong Guo,1,2,* Wang Jing,2,3,* Hui Zhu,2 Minghuan Li,2 Bing Zou,2 Yan Zhang,2 Lei Fu,2 Li Kong,2 Jinbo Yue,2,4 Jinming Yu2,4 1Department of Oncology, Clinical College, Weifang Medical University, Weifang, Shandong Province, People’s Republic of ...
Li MH   +9 more
core  

Benchmarked Colorectal Cancer Outcomes in a Metropolitan Hospital: A 5‐Year Review

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
In metastatic disease, patients with lung‐only metastasis had the best 5‐year survival at 46.0% and curative‐intent approaches can dramatically improve survival. ABSTRACT Introduction Colorectal cancer (CRC) remains a major contributor to cancer‐related mortality worldwide, with survival influenced by many prognostic factors.
Jialin Du   +3 more
wiley   +1 more source

Carcinoembryonic antigen glycosylation: revealing novel features of human glycosylation and cancer origin specificity

open access: yes, 2020
Carcinoembryonic Antigen (CEA) is a biomarker strongly associated with tumour progression and metastasis. Even though N-glycans make up »50% of the entire CEA molecule, current knowledge on CEA specific glycosylation in health and disease is scarce.
Almeida, Andreia   +8 more
core  

Carcinoembryonic antigen in sweat-gland carcinomas

open access: yes, 1982
Using standard immunoperoxidase techniques, four cases of malignant sweat-gland carcinoma were examined for the presence of carcinoembryonic antigen (CEA).
Penneys, N S   +4 more
core   +1 more source

Impact of RAS/RAF Mutations on Metastatic Treatment Response Following Total Neoadjuvant Therapy in Patients With Stage IV Rectal Cancer

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
There is limited understanding of the impact of underlying RAS/RAF mutational status on total neoadjuvant therapy metastatic tumor response rates in curative Stage IV rectal cancer patients. Complete metastatic tumor response to TNT was demonstrated in half as many mRAS as wtRAS patients and disease progression was higher in patients harboring RAS ...
Tracy R. Fitzsimmons   +8 more
wiley   +1 more source

Carcinoembryonic Antigen and the Liver

open access: yesGastroenterology, 1977
M S, Loewenstein, N, Zamcheck
openaire   +2 more sources

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