Results 191 to 200 of about 91,344 (325)

Total neoadjuvant therapy in rectal cancer: The FOREST protocol, a patient‐centered approach that clusters two cohorts with different outcomes

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 697-706, 1 February 2026.
What's new? Treatment strategies for rectal cancer are increasingly focused on organ preservation and tailored therapy. Total neoadjuvant therapy (TNT), which integrates radiotherapy and systemic chemotherapy prior to surgery, is especially promising in this regard.
Hector Guadalajara   +14 more
wiley   +1 more source

Radiogenomics: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang   +8 more
wiley   +1 more source

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao   +8 more
wiley   +1 more source

Carcinoembryonic antigen in normal, preneoplastic and neoplastic gallbladder epithelium [PDF]

open access: bronze, 1983
Jorge Albores‐Saavedra   +3 more
openalex   +1 more source

Novel Drug‐Disease Modeling Framework for Oncology Benefit–Risk Evaluation: Application to Tusamitamab Ravtansine

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT This study introduces a novel drug‐disease modeling framework designed to assess the benefit–risk balance of antibody‐drug conjugates (ADC) in oncology. The framework integrates dose levels, pharmacokinetics, tumor growth dynamics, progression‐free survival (PFS), and dose‐adjusted adverse events.
Marc Cerou   +8 more
wiley   +1 more source

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