Results 61 to 70 of about 84,117 (291)

Advances in the design and development of oncolytic measles viruses. [PDF]

, 2015
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian, Raffel, Corey, Studebaker, Adam W   +2 more
core   +1 more source

Reactive oxygen species modulator 1, a novel protein, combined with carcinoembryonic antigen in differentiating malignant from benign pleural effusion

Tumor Biology, 2017
The differential diagnosis of malignant pleural effusion and benign pleural effusion remains a clinical problem. Reactive oxygen species modulator 1 is a novel protein overexpressed in various human tumors. The objective of this study was to evaluate the
Xianmeng Chen, Na Zhang, Jiahui Dong, Gengyun Sun   +3 more
doaj   +1 more source

Ultrasensitive immunosensor for detecting CEA based on double amplified signal of graphene loaded CoFe2O4/Ag nanoparticles

Micro & Nano Letters, 2021
Using Ag‐CoFe2O4‐GO nanocomposite as biosensor interface, a novel unlabelled electrochemical immunosensor was designed to detect tumour marker carcinoembryonic antigen. Here, Ag‐CoFe2O4‐GO was synthesized by one‐pot method as an immunological probe. They
Xiao Wang, Mei Wu, Chulei Zhao, Xiaochen Liao, Mengmeng Zhang, Lisha Mei, XiuWen Qiao, Chenglin Hong   +7 more
doaj   +1 more source

High‐Sensitivity Terahertz Gas Sensing Enabled by Undercut Metal‐Dielectric‐Metal Metamaterial

Advanced Materials Interfaces, EarlyView.
A terahertz (THz) metamaterial gas sensor is demonstrated using a metal–dielectric–metal (MDM) absorber with an undercut dielectric layer, which enlarges the gas‐replaced volume and strengthens refractive‐index perturbation of the resonant mode. A reflection dip at 0.766 THz is observed, and acetone–nitrogen tests yield concentration‐dependent shifts ...
Naoki Inomata, Yuki Sakai, Yoshiaki Kanamori   +2 more
wiley   +1 more source

Markers of inflammation and bone remodelling associated with improvement in clinical response measures in psoriatic arthritis patients treated with golimumab [PDF]

, 2013
<p>Objective To determine serum biomarker associations with clinical response to golimumab treatment in patients with psoriatic arthritis (PsA).</p> <p>Methods GO–REVEAL was a randomised, placebo-controlled study of golimumab in ...
Beutler, A., Elashoff, M., Gladman, D., Gomez-Reino, J.J., Kavanaugh, A., Krueger, G.G., Mack, M., McInnes, I.B., Mease, P.J., Murphy, F.T., Papp, K., Visvanathan, S., Wagner, C.L.   +12 more
core   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Radionuclide-Based Cancer Imaging Targeting the Carcinoembryonic Antigen

Biomarker Insights, 2008
Carcinoembryonic antigen (CEA), highly expressed in many cancer types, is an important target for cancer diagnosis and therapy. Radionuclide-based imaging techniques (gamma camera, single photon emission computed tomography [SPECT] and positron emission ...
Hao Hong, Jiangtao Sun, Weibo Cai Ph.D.
doaj   +2 more sources

Targeted therapy of advanced gallbladder cancer and cholangiocarcinoma with aggressive biology: eliciting early response signals from phase 1 trials. [PDF]

, 2013
PurposePatients with advanced cholangiocarcinoma (CC) and gallbladder carcinoma (GC) have few therapeutic options for relapsed disease. methods: Given the overall poor prognosis in this population and the availability of novel targeted therapies, we ...
Falchook, Gerald S, Fu, Siqing, Hess, Kenneth R, Hong, David S, Janku, Filip, Javle, Milind, Kaseb, Ahmed O, Kurzrock, Razelle, Naing, Aung, Piha-Paul, Sarina, Subbiah, Ishwaria M, Subbiah, Vivek, Tsimberidou, Apostolia M, Wheler, Jennifer J, Wolff, Robert A   +14 more
core   +2 more sources

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Graphene Quantum Dot-Based Electrochemical Immunosensors for Biomedical Applications [PDF]

, 2019
In the area of biomedicine, research for designing electrochemical sensors has evolved over the past decade, since it is crucial to selectively quantify biomarkers or pathogens in clinical samples for the efficacious diagnosis and/or treatment of various
Altintas, Zeynep, Mansuriya, Bhargav D.
core   +1 more source